The modular architecture of meningococcal factor H-binding protein

Microbiology

Volumn 155, Issue 9, 2009, Pages 2873-2883

  Beemink, Peter T ^a   Granoff, Dan M ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; MENINGOCOCCAL FACTOR H BINDING PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE CLUSTER; GENETIC VARIABILITY; NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PHYLOGENY; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; DNA, BACTERIAL; EVOLUTION, MOLECULAR; GENETIC VARIATION; HUMANS; MENINGOCOCCAL INFECTIONS; MENINGOCOCCAL VACCINES; NEISSERIA MENINGITIDIS; PHYLOGENY; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, PROTEIN; STRUCTURAL HOMOLOGY, PROTEIN;

NEISSERIA GONORRHOEAE; NEISSERIA MENINGITIDIS;

EID: 69949174776     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.029876-0     Document Type: Article

References (37)

1. Arreaza, L., Alcala, B., Salcedo, C., de la Fuente, L. & Vazquez, J. A. (2003). Dynamics of the penA gene in serogroup C meningococcal strains. J Infect Dis 187, 1010-1014.
2. Bambini, S., Muzzi, A., Olcen, P., Rappuoli, R., Pizza, M. & Comanducci, M. (2009). Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus. Vaccine 27, 2794-2803.
3. Beernink, P. T. & Granoff, D. M. (2008). Bactericidal antibody responses induced by meningococcal recombinant chimeric factor H-binding protein vaccines. Infect Immun 76, 2568-2575.
4. Beernink, P. T., Welsch, J. A., Harrison, L. H., Leipus, A., Kaplan, S. L. & Granoff, D. M. (2007). Prevalence of factor H-binding protein variants and NadA among meningococcal group B isolates from the United States: implications for the development of a multicomponent group B vaccine. J Infect Dis 195, 1472-1479.
5. Beernink, P. T., Welsch, J. A., Bar-Lev, M., Koeberling, O., Comanducci, M. & Granoff, D. M. (2008). Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate, factor H-binding protein. Infect Immun 76, 4232-4240.
6. Beernink, P. T., Caugant, D. A., Welsch, J. A., Koeberling, O. & Granoff, D. M. (2009a). Meningococcal factor H-binding protein variants expressed by epidemic capsular group A, W-135, and X strains from Africa. J Infect Dis 199, 1360-1368.
7. Beernink, P. T., Lopasso, C., Angiolillo, A., Felici, F. & Granoff, D. (2009b). A region of the N-terminal domain of meningococcal factor H-binding protein that elicits bactericidal antibody across anigenic variant groups. Mol Immunol 46, 1647-1653.
8. Bentley, S. D., Vernikos, G. S., Snyder, L. A., Churcher, C., Arrowsmith, C., Chillingworth, T., Cronin, A., Davis, P. H., Holroyd, N. E. & other authors (2007). Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18. PLoS Genet 3, e23.
9. Bilek, N., Ison, C. A. & Spratt, B. G. (2009). Relative contributions of recombination and mutation to the diversification of the opa gene repertoire of Neisseria gonorrhoeae. J Bacteriol 191, 1878-1890.
10. Callaghan, M. J., Buckee, C. O., Jolley, K. A., Kriz, P., Maiden, M. C. & Gupta, S. (2008). The effect of immune selection on the structure of the meningococcal Opa protein repertoire. PLoS Pathog 4, e1000020.
11. Castresana, J. (2000). Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. Mol Biol Evol 17, 540-552.
12. Dereeper, A., Guignon, V., Blanc, G., Audic, S., Buffet, S., Chevenet, F., Dufayard, J. F., Guindon, S., Lefort, V. & other authors (2008). Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Res 36, W465-W469.
13. Edgar, R. C. (2004). MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res 32, 1792-1797.
14. Fletcher, L. D., Bernfield, L., Barniak, V., Farley, J. E., Howell, A., Knauf, M., Ooi, P., Smith, R. P., Weise, P. & other authors (2004). Vaccine potential of the Neisseria meningitidis 2086 lipoprotein. Infect Immun 72, 2088-2100.
15. Giuliani, M. M., Santini, L., Brunelli, B., Biolchi, A., Aricò, B., Di Marcello, F., Cartocci, E., Comanducci, M., Masignani, V. & other authors (2005). The region comprising amino acids 100 to 255 of Neisseria meningitidis lipoprotein GNA 1870 elicits bactericidal antibodies. Infect Immun 73, 1151-1160.
16. Granoff, D. M., Welsch, J. A. & Ram, S. (2009). Binding of complement factor H (fH) to Neisseria meningitidis is specific for human fH and inhibits complement activation by rat and rabbit sera. Infect Immun 77, 764-769.
17. Guindon, S. & Gascuel, O. (2003). A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst Biol 52, 696-704.
18. Hotopp, J. C., Grifantini, R., Kumar, N., Tzeng, Y. L., Fouts, D., Frigimelica, E., Draghi, M., Giuliani, M. M., Rappuoli, R. & other authors (2006). Comparative genomics of Neisseria meningitidis: core genome, islands of horizontal transfer and pathogen-specific genes. Microbiology 152, 3733-3749.
19. Jacobsson, S., Hedberg, S. T., Molling, P., Unemo, M., Comanducci, M., Rappuoli, R. & Olcen, P. (2009). Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal disease. Vaccine 27, 1579-1584.
20. Jansen, K. U., McNeil, L. K., Dragalin, V., Anderson, A. S., Hoiseth, S. K., Arora, A., Emini, E. E., Zlotnick, G. W. & Jones, T. (2008). Bivalent recombinant LP2086 vaccine to provide broad protection against Neisseria meningitidis B disease: immunological correlates of protection and how to assess coverage against invasive MnB strains. Abstract number 064 in 16th International Pathogenic Neisseria Conference, Rotterdam, The Netherlands, September 7-12 2008. Edited by L. van Alphen, P. van der Ley & G. van den Dobbelsteen (http://neisseria.org/ipnc/2008/ Abstracts_oral_presentations_IPNC_2008.pdf).
21. Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A. & other authors (2007). CLUSTAL W and CLUSTAL_X version 2.0. Bioinformatics 23, 2947-2948.
22. Madico, G., Welsch, J. A., Lewis, L. A., McNaughton, A., Perlman, D. H., Costello, C. E., Ngampasutadol, J., Vogel, U., Granoff, D. M. & Ram, S. (2006). The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance. J Immunol 177, 501-510.
23. Marshall, H., Nissen, M. D., Richmond, P., Lambert, S. B., Roberton, D. M., Jones, T., Lockhart, S., Gruber, W. & Arona, A. (2008). A randomized, placebo-controlled, double-blind, phase 1 trial of ascending doses of meningococcal group B rLP2086 vaccine in healthy adults. Abstract number P213 in 16th International Pathogenic Neisseria Conference, Rotterdam, The Netherlands, September 7-12 2008. Edited by L. van Alphen, P. van der Ley & G. van den Dobbelsteen. (http://neisseria.org/ipnc/2008/Abstracts_oral_presentations_ IPNC_2008.pdf).
24. Masignani, V., Comanducci, M., Giuliani, M. M., Bambini, S., Adu-Bobie, J., Arico, B., Brunelli, B., Pieri, A., Santini, L. & other authors (2003). Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870. J Exp Med 197, 789-799.
25. Ochiai, S., Ishiko, H., Yasuda, M. & Deguchi, T. (2008). Rapid detection of the mosaic structure of the Neisseria gonorrhoeae penA gene, which is associated with decreased susceptibilities to oral cephalosporins. J Clin Microbiol 46, 1804-1810.
26. Plested, J. S., Welsch, J. A. & Granoff, D. M. (2009). Ex vivo model of meningococcal bacteremia using human blood for measuring vaccine-induced serum passive protective activity. Clin Vaccine Immunol 16, 785-791.
27. Rappuoli, R. (2008). The application of reverse vaccinology, Novartis MenB vaccine developed by design. Abstract number 065 in 16th International Pathogenic Neisseria Conference, Rotterdam, The Netherlands, September 7-12 2008. Edited by L. van Alphen, P. van der Ley & G. van den Dobbelsteen. (http://neisseria.org/ipnc/2008/ Abstracts_oral_presentations_IPNC_2008.pdf).
28. Richmond, P., Marshall, H., Nissen, M. D., Lambert, S., Jones, T., Gruber, W. & Arora, A. (2008). A randomized, observer-blinded, active control, phase 1 trial of meningococcal serogroup B rLP2086 vaccine in healthy children and adolescents aged 8 to 14 years. Abstract number P2132 in 16th International Pathogenic Neisseria Conference, Rotterdam, The Netherlands, September 7-12 2008. Edited by L. van Alphen, P. van der Ley & G. van den Dobbelsteen. (http://neisseria.org/ipnc/2008/Abstracts_oral_presentations_ IPNC_2008.pdf).
29. Rokbi, B., Maitre-Wilmotte, G., Mazarin, V., Fourrichon, L., Lissolo, L. & Quentin-Millet, M. J. (1995). Variable sequences in a mosaic-like domain of meningococcal tbp2 encode immunoreactive epitopes. FEMS Microbiol Lett 132, 277-283.
30. Scarselli, M., Cantini, F., Santini, L., Veggi, D., Dragonetti, S., Donati, C., Savino, S., Giuliani, M. M., Comanducci, M. & other authors (2009). Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis. J Mol Biol 386, 97-108.
31. Schneider, M. C., Exley, R. M., Chan, H., Feavers, I., Kang, Y. H., Sim, R. B. & Tang, C. M. (2006). Functional significance of factor H binding to Neisseria meningitidis. J Immunol 176, 7566-7575.
32. Schneider, M. C., Prosser, B. E., Caesar, J. J., Kugelberg, E., Li, S., Zhang, Q., Quoraishi, S., Lovett, J. E., Deane, J. E. & other authors (2009). Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates. Nature 458, 890-893.
33. Snape, M. D., Dawson, T., Morant, A., John, B., Ohene-Kena, R., Borrow, R., Oster, P. & Pollard, A. J. (2008). Immunogenicity and reactogenicity of a novel serogroup B Neisseria meningitidis vaccine administered from 6 months of age. Abstract number 069 in 16th International Pathogenic Neisseria Conference, Rotterdam, The Netherlands, September 7-12 2008. Edited by L. van Alphen, P. van. der Ley & G. van den Dobbelsteen. (http://neisseria.org/ipnc/2008/ Abstracts_oral_presentations_IPNC_2008.pdf).
34. Szczesny, P. & Lupas, A. (2008). Domain annotation of trimeric autotransporter adhesins - daTAA. Bioinformatics 24, 1251-1256.
35. Tamura, K., Dudley, J., Nei, M. & Kumar, S. (2007). MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 24, 1596-1599.
36. Welsch, J. A., Rossi, R., Comanducci, M. & Granoff, D. M. (2004). Protective activity of monoclonal antibodies to genome-derived neisserial antigen 1870, a Neisseria meningitidis candidate vaccine. J Immunol 172, 5606-5615.
37. Welsch, J. A., Ram, S., Koeberling, O. & Granoff, D. M. (2008). Complement-dependent synergistic bactericidal activity of antibodies against factor H-binding protein, a sparsely distributed meningococcal vaccine antigen. J Infect Dis 197, 1053-1061.