Schlafen-3: A novel regulator of intestinal differentiation

Biochemical and Biophysical Research Communications

Volumn 388, Issue 4, 2009, Pages 752-756

  Patel, Vaishali B ^a,b   Yu, Yingjie ^a,b   Das, Jayanta K ^a,b   Patel, Bhaumik B ^a,b   Majumdar, Adhip P N ^a,b  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alkaline phosphatase; Butyrate; Intestinal differentiation; Schlafen 3

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; BUTYRIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR 1B; REGULATOR PROTEIN; RNA; SCHLAFEN 3; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INTESTINE CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RECOMBINANT PLASMID; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SCHLAFEN 3 GENE; SIGNAL TRANSDUCTION; TRANSIENT TRANSFECTION; WESTERN BLOTTING;

ANIMALS; BUTYRATES; CADHERINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; HUMANS; INTESTINAL MUCOSA; INTESTINES; PROTEINS; RATS; RNA, SMALL INTERFERING; TRANSFORMING GROWTH FACTOR ALPHA;

RATTUS;

EID: 69949167597     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.08.094     Document Type: Article

References (26)

1. van der Flier L.G., and Clevers H. Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu. Rev. Physiol. 71 (2009) 241-260
2. Cheng H., and Leblond C.P. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types. Am. J. Anat. 141 (1974) 537-561
3. Jenny M., Uhl C., Roche C., Duluc I., Guillermin V., Guillemot F., Jensen J., Kedinger M., and Gradwohl G. Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J. 21 (2002) 6338-6347
4. Ng A.Y., Waring P., Ristevski S., Wang C., Wilson T., Pritchard M., Hertzog P., and Kola I. Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium. Gastroenterology 122 (2002) 1455-1466
5. Blache P., van de Wetering M., Duluc I., Domon C., Berta P., Freund J.N., Clevers H., and Jay P. SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes. J. Cell Biol. 166 (2004) 37-47
6. Katz J.P., Perreault N., Goldstein B.G., Lee C.S., Labosky P.A., Yang V.W., and Kaestner K.H. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 129 (2002) 2619-2628
7. Patel B.B., Yu Y., Du J., Rishi A.K., Sarkar F.H., Tarca A.L., Wali A., and Majumdar A.P. Schlafen 3, a novel gene, regulates colonic mucosal growth during aging. Am. J. Physiol. Gastrointest. Liver Physiol. 296 (2009) G955-G962
8. Schwarz D.A., Katayama C.D., and Hedrick S.M. Schlafen, a new family of growth regulatory genes that affect thymocyte development. Immunity 9 (1998) 657-668
9. Geserick P., Kaiser F., Klemm U., Kaufmann S.H., and Zerrahn J. Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif. Int. Immunol. 16 (2004) 1535-1548
10. Hanson P.I., and Whiteheart S.W. AAA+ proteins: have engine, will work. Nat. Rev. Mol. Cell Biol. 6 (2005) 519-529
11. Mackintosh S.G., and Raney K.D. DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases. Nucleic Acids Res. 34 (2006) 4154-4159
12. Fuller-Pace F.V. RNA helicases: modulators of RNA structure. Trends Cell Biol. 4 (1994) 271-274
13. Brady G., Boggan L., Bowie A., and O'Neill L.A. Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1. J. Biol. Chem. 280 (2005) 30723-30734
14. Sohn W.J., Kim D., Lee K.W., Kim M.S., Kwon S., Lee Y., Kim D.S., and Kwon H.J. Novel transcriptional regulation of the schlafen-2 gene in macrophages in response to TLR-triggered stimulation. Mol. Immunol. 44 (2007) 3273-3282
15. Neumann B., Zhao L., Murphy K., and Gonda T.J. Subcellular localization of the Schlafen protein family. Biochem. Biophys. Res. Commun. 370 (2008) 62-66
16. Lee N.K., Choi H.K., Yoo H.J., Shin J., and Lee S.Y. RANKL-induced schlafen2 is a positive regulator of osteoclastogenesis. Cell. Signal. 20 (2008) 2302-2308
17. Kirkland J.L., Hollenberg C.H., and Gillon W.S. Ageing, differentiation, and gene expression in rat epididymal preadipocytes. Biochem. Cell Biol. 71 (1993) 556-561
18. Patel B.B., Sengupta R., Qazi S., Vachhani H., Yu Y., Rishi A.K., and Majumdar A.P. Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R. Int. J. Cancer 122 (2008) 267-273
19. Cummings J.H., Pomare E.W., Branch W.J., Naylor C.P., and Macfarlane G.T. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut 28 (1987) 1221-1227
20. Chung Y.S., Song I.S., Erickson R.H., Sleisenger M.H., and Kim Y.S. Effect of growth and sodium butyrate on brush border membrane-associated hydrolases in human colorectal cancer cell lines. Cancer Res. 45 (1985) 2976-2982
21. Massague J. The transforming growth factor-beta family. Annu. Rev. Cell Biol. 6 (1990) 597-641
22. Siavoshian S., Segain J.P., Kornprobst M., Bonnet C., Cherbut C., Galmiche J.P., and Blottiere H.M. Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression. Gut 46 (2000) 507-514
23. Fukushima K., Sasaki I., Hasegawa H., Takahashi K., Naito H., Funayama Y., and Matsuno S. Sodium butyrate-induced liver-type alkaline phosphatase activity in a small intestinal epithelial cell line, IEC6. Dig. Dis. Sci. 43 (1998) 1116-1123
24. Deschenes C., Vezina A., Beaulieu J.F., and Rivard N. Role of p27(Kip1) in human intestinal cell differentiation. Gastroenterology 120 (2001) 423-438
25. Lecanda J., Parekh T.V., Gama P., Lin K., Liarski V., Uretsky S., Mittal K., and Gold L.I. Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium. Cancer Res. 67 (2007) 1007-1018
26. Litvak D.A., Evers B.M., Hwang K.O., Hellmich M.R., Ko T.C., and Townsend Jr. C.M. Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1. Surgery 124 (1998) 161-169 (discussion 169-170)