Involvement of ergosterol in tolerance to vanillin, a potential inhibitor of bioethanol fermentation, in Saccharomyces cerevisiae

FEMS Microbiology Letters

Volumn 299, Issue 1, 2009, Pages 95-99

  Endo, Ayako ^a   Nakamura, Toshihide ^a   Shima, Jun ^a  

^a NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

Author keywords

Bioethanol; Ergosterol; Fermentation inhibitor; Saccharomyces cerevisiae; Vanillin

Indexed keywords

ALCOHOL; ERGOSTEROL; VANILLIN;

ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; FERMENTATION INHIBITION; FUNGAL GENE; FUNGAL STRAIN; GENE EXPRESSION REGULATION; LIPOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SCREENING; STRAIN DIFFERENCE; UPREGULATION;

BENZALDEHYDES; ERGOSTEROL; ETHANOL; FERMENTATION; GENE EXPRESSION REGULATION, FUNGAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 69949164861     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2009.01733.x     Document Type: Article

References (23)

1. +-ATPase activity and the lipid composition of the plasma membrane in different wine yeast strains. Int J Food Microbiol 110 : 34 42.
2. Alexandre H, Rousseaux I Charpentier C (1994) Relationship between ethanol tolerance, lipid composition and plasma membrane fluidity in Saccharomyces cerevisiae and Kloeckera apiculata. FEMS Microbiol Lett 124 : 17 22.
3. Basson ME, Thorsness M Rine J (1986) Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase. P Natl Acad Sci USA 83 : 5563 5567.
4. Daum G, Lees ND, Bard M Dickson R (1998) Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae. Yeast 14 : 1471 1510.
5. Endo A, Nakamura T, Ando A, Tokuyasu K Shima J (2008) Genome-wide screening of the genes required for tolerance to vanillin, which is a potential inhibitor of bioethanol fermentation, in Saccharomyces cerevisiae. Biotechnol Biofuels 1 : 3.
6. Fitzgerald DJ, Stratford M Narbad A (2003) Analysis of the inhibition of food spoilage yeasts by vanillin. Int J Food Microbiol 86 : 113 122.
7. Gaisne M, Becam AM, Verdiere J Herbert CJ (1999) A 'natural' mutation in Saccharomyces cerevisiae strains derived from S288c affects the complex regulatory gene HAP1 (CYP1). Curr Genet 36 : 195 200.
8. Galbe M Zacchi G (2002) A review of the production of ethanol from softwood. Appl Microbiol Biot 59 : 618 628.
9. Gray KA, Zhao L Emptage M (2006) Bioethanol. Curr Opin Chem Biol 10 : 141 146.
10. Hahn-Hagerdal B, Galbe M, Gorwa-Grauslund MF, Liden G Zacchi G (2006) Bio-ethanol - the fuel of tomorrow from the residues of today. Trends Biotechnol 24 : 549 556.
11. Klinke HB, Thomsen AB Ahring BK (2004) Inhibition of ethanol-producing yeast and bacteria by degradation products produced during pre-treatment of biomass. Appl Microbiol Biot 66 : 10 26.
12. Knox AM, du Preez JC Kilian SG (2004) Starch fermentation characteristics of Saccharomyces cerevisiae strains transformed with amylase genes from Lipomyces kononenkoae and Saccharomycopsis fibuligera. Enzyme Microb Tech 34 : 453 460.
13. Kwast KE, Burke PV Poyton RO (1998) Oxygen sensing and the transcriptional regulation of oxygen-responsive genes in yeast. J Exp Biol 201 : 1177 1195.
14. McMillan JD (1994) Pretreatment of lignocellulosic biomass. Enzymatic Conversion of Biomass for Fuels Production, Vol. 566 (Himmel ME, Baker JO Overend RP, eds). 292 324, American Chemical Society, Washington, DC.
15. Mo C, Valachovic M, Randall SK, Nickels JT Bard M (2002) Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis. P Natl Acad Sci USA 99 : 9739 9744.
16. Mo C, Valachovic M Bard M (2004) The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). Biochim Biophys Acta 1686 : 30 36.
17. Olsson L Hahn-Hagerdal B (1996) Fermentation of lignocellulosic hydrolysates for ethanol production. Enzyme Microb Tech 18 : 312 331.
18. Palmqvist E Hahn-Hagerdal B (2000) Fermentation of lignocellulosic hydrolysates. II: inhibitors and mechanisms of inhibition. Bioresour Technol 74 : 25 33. (Pubitemid 30190275)
19. Polakowski T, Stahl U Lang C (1998) Overexpression of a cytosolic hydroxymethylglutaryl-CoA reductase leads to squalene accumulation in yeast. Appl Microbiol Biot 49 : 66 71.
20. Saha BC (2003) Hemicellulose bioconversion. J Ind Microbiol Biot 30 : 279 291.
21. Tamura K, Gu Y, Wang Q, Yamada T, Ito K Shimoi H (2004) A hap1 mutation in a laboratory strain of Saccharomyces cerevisiae results in decreased expression of ergosterol-related genes and cellular ergosterol content compared to sake yeast. J Biosci Bioeng 98 : 159 166.
22. Tanaka-Tsuno F, Mizukami-Murata S, Murata Y, Nakamura T, Ando A, Takagi H Shima J (2007) Functional genomics of commercial baker's yeasts that have different abilities for sugar utilization and high-sucrose tolerance under different sugar conditions. Yeast 24 : 901 911.
23. Zinser E, Sperka-Gottlieb CD, Fasch EV, Kohlwein SD, Paltauf F Daum G (1991) Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiae. J Bacteriol 173 : 2026 2034.