Large crystal growth by thermal control allows combined X-ray and neutron crystallographic studies to elucidate the protonation states in Aspergillus flavus urate oxidase

Journal of the Royal Society Interface

Volumn 6, Issue SUPPL. 5, 2009, Pages

  Oksanen, E ^a,b   Blakeley, M P ^c   Bonnete F ^d   Dauvergne, M T ^b   Dauvergne, F ^b   Budayova Spano, M ^b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

^c INSTITUT LAUE LANGEVIN   (France)

^d AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

Crystal growth; H D exchange; Neutron and X ray crystallography; Phase diagram; Protonation states; Urate oxidase

Indexed keywords

CATALYSIS; CHEMOTHERAPY; CRYSTAL GROWTH; CRYSTALLIZATION; CYANIDES; DEUTERIUM; GRAIN BOUNDARIES; MINERALOGY; NEUTRONS; PHASE DIAGRAMS; PROTONATION; QUANTUM CHEMISTRY; SELF ASSEMBLY; SINGLE CRYSTALS; SUBSTRATES; X RAYS;

ALLANTOINS; ASPERGILLUS FLAVUS; CATALYTIC MECHANISMS; CRYSTALLIZATION PROCESS; CRYSTALLOGRAPHIC STUDIES; DIRECT DETERMINATION; EUROPEAN SYNCHROTRON RADIATION FACILITIES; H-D EXCHANGE; HIGH RESOLUTION; LANGEVIN; LARGE CRYSTAL; NATURAL SUBSTRATES; NEUTRON CRYSTALLOGRAPHY; NEUTRON DIFFRACTION DATA; NUCLEAR SCATTERING; PROTONATION STATE; PROTONATION STATES; ROOM TEMPERATURE; STRUCTURAL DIFFERENCES; THERMAL CONTROL; URATE OXIDASE; X RAY DATA; X-RAY STRUCTURE; X-RAY STUDIES;

X RAY CRYSTALLOGRAPHY;

8 AZAXANTHINE; 9 METHYLURATE; CYANIDE; UNCLASSIFIED DRUG; URATE; URATE OXIDASE; XANTHINE DERIVATIVE;

ASPERGILLUS FLAVUS; CHEMICAL REACTION; CONFERENCE PAPER; CRYSTALLIZATION; CRYSTALLOGRAPHY; DEUTERIUM HYDROGEN EXCHANGE; NEUTRON CRYSTALLOGRAPHY; NEUTRON DIFFRACTION; NONHUMAN; PROTEIN STRUCTURE; PROTON TRANSPORT; THERMAL EXPOSURE; X RAY CRYSTALLOGRAPHY;

ASPERGILLUS FLAVUS;

ASPERGILLUS FLAVUS; CRYSTALLOGRAPHY; NEUTRON DIFFRACTION; PROTEIN CONFORMATION; PROTONS; URATE OXIDASE; X-RAY DIFFRACTION;

EID: 69949156416     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2009.0162.focus     Document Type: Conference Paper

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