Airway-specific recruitment of T cells is reduced in a CD26-deficient F344 rat substrain

Clinical and Experimental Immunology

Volumn 158, Issue 1, 2009, Pages 133-142

  Schade, J ^a   Schmiedl, A ^a   Kehlen, A ^b   Veres, T Z ^c   Stephan, M ^a   Pabst, R ^a   Von Horsten S ^d  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b PROBIODRUG AG   (Germany)

^c FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Asthma; Bronchi; CD26 dipeptidyl peptidase 4; F344 rat substrains; T cells

Indexed keywords

CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; DIPEPTIDYL PEPTIDASE IV; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN E; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; STROMAL CELL DERIVED FACTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CONTROLLED STUDY; EOSINOPHIL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD26; ASTHMA; BRONCHI; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOTAXIS, LEUKOCYTE; IMMUNOGLOBULIN E; IMMUNOHISTOCHEMISTRY; LUNG; LYMPHOCYTE COUNT; MALE; MODELS, ANIMAL; OVALBUMIN; RATS; RATS, INBRED F344; RATS, MUTANT STRAINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STATISTICS, NONPARAMETRIC; T-LYMPHOCYTES;

EID: 69949126780     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2009.03991.x     Document Type: Article

References (37)

1. Bousquet J, Jeffery PK, Busse WW, Johnson M, Vignola AM. Asthma. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med 2000 161 : 1720 1745.
2. Szelenyi I. Animal models of bronchial asthma. Inflamm Res 2000 49 : 639 654.
3. Tschernig T, Neumann D, Pich A, Dorsch M, Pabst R. Experimental bronchial asthma - the strength of the species rat. Curr Drug Targets 2008 9 : 466 469.
4. Skripuletz T, Schmiedl A, Schade J et al. Dose-dependent recruitment of CD25+ and CD26+ T cells in a novel F344 rat model of asthma. Am J Physiol Lung Cell Mol Physiol 2007 292 : L1564 71.
5. Boonacker E, Van Noorden CJ. The multifunctional or moonlighting protein CD26/DPPIV. Eur J Cell Biol 2003 82 : 53 73.
6. De Meester I, Korom S, Van Damme J, Scharpe S. CD26, let it cut or cut it down. Immunol Today 1999 20 : 367 375.
7. Mentlein R. Dipeptidyl-peptidase IV (CD26) - role in the inactivation of regulatory peptides. Regul Pept 1999 85 : 9 24.
8. Schade J, Stephan M, Schmiedl A et al. Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats. J Histochem Cytochem 2008 56 : 147 155.
9. Allen M, Heinzmann A, Noguchi E et al. Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet 2003 35 : 258 263.
10. Zagha E, Ozaita A, Chang SY et al. DPP10 modulates Kv4-mediated A-type potassium channels. J Biol Chem 2005 280 : 18853 18861.
11. Kerzel S, Path G, Nockher WA et al. Pan-neurotrophin receptor p75 contributes to neuronal hyperreactivity and airway inflammation in a murine model of experimental asthma. Am J Respir Cell Mol Biol 2003 28 : 170 178.
12. Nassenstein C, Kammertoens T, Veres TZ et al. Neuroimmune crosstalk in asthma: dual role of the neurotrophin receptor p75NTR. J Allergy Clin Immunol 2007 120 : 1089 1096.
13. Tsuji E, Misumi Y, Fujiwara T, Takami N, Ogata S, Ikehara Y. An active-site mutation (Gly633-> Arg) of dipeptidyl peptidase IV causes its retention and rapid degradation in the endoplasmic reticulum. Biochemistry 1992 31 : 11921 11927.
14. Kruschinski C, Skripuletz T, Bedoui S et al. CD26 (dipeptidyl-peptidase IV)-dependent recruitment of T cells in a rat asthma model. Clin Exp Immunol 2005 139 : 17 24.
15. Karl T, Chwalisz WT, Wedekind D et al. Localization, transmission, spontaneous mutations, and variation of function of the Dpp4 (dipeptidyl-peptidase IV; CD26) gene in rats. Regul Pept 2003 115 : 81 90.
16. Rehbinder C, Baneux P, Forbes D et al. FELASA recommendations for the health monitoring of mouse, rat, hamster, gerbil, guinea pig and rabbit experimental units. Report of the Federation of European Laboratory Animal Science Associations (FELASA) Working Group on Animal Health accepted by the FELASA Board of Management, November 1995. Lab Anim 1996 30 : 193 208.
17. Cordell JL, Falini B, Erber WN et al. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984 32 : 219 229.
18. West MJ, Slomianka L, Gundersen HJ. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 1991 231 : 482 497.
19. Schmiedl A, Luhrmann A, Pabst R, Koslowski R. Increased surfactant protein A and D expression in acute ovalbumin-induced allergic airway inflammation in Brown Norway rats. Int Arch Allergy Immunol 2008 148 : 118 126.
20. Kehlen A, Lendeckel U, Dralle H, Langner J, Hoang-Vu C. Biological significance of aminopeptidase N/CD13 in thyroid carcinomas. Cancer Res 2003 63 : 8500 8506.
21. Faul JL, Tormey VJ, Leonard C et al. Lung immunopathology in cases of sudden asthma death. Eur Respir J 1997 10 : 301 307.
22. Lukacs NW, Strieter RM, Warmington K, Lincoln P, Chensue SW, Kunkel SL. Differential recruitment of leukocyte populations and alteration of airway hyperreactivity by C-C family chemokines in allergic airway inflammation. J Immunol 1997 158 : 4398 4404.
23. Gavett SH, Chen X, Finkelman F, Wills-Karp M. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia. Am J Respir Cell Mol Biol 1994 10 : 587 593.
24. Hanski C, Huhle T, Gossrau R, Reutter W. Direct evidence for the binding of rat liver DPP IV to collagen in vitro. Exp Cell Res 1988 178 : 64 72.
25. Piazza GA, Callanan HM, Mowery J, Hixson DC. Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix. Biochem J 1989 262 : 327 334.
26. Cheng HC, Abdel-Ghany M, Elble RC, Pauli BU. Lung endothelial dipeptidyl peptidase IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin. J Biol Chem 1998 273 : 24207 24215. (Pubitemid 28435768)
27. Mattern T, Reich C, Schonbeck U et al. CD26 (dipeptidyl peptidase i.v.) on human T lymphocytes does not mediate adhesion of these cells to endothelial cells or fibroblasts. Immunobiology 1998 198 : 465 475.
28. Forssmann U, Stoetzer C, Stephan M et al. Inhibition of CD26/dipeptidyl peptidase IV enhances CCL11/eotaxin-mediated recruitment of eosinophils in vivo. J Immunol 2008 181 : 1120 1127.
29. Gonzalo JA, Lloyd CM, Wen D et al. The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness. J Exp Med 1998 188 : 157 167.
30. Alam R, York J, Boyars M et al. Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients. Am J Respir Crit Care Med 1996 153 : 1398 1404. (Pubitemid 26112608)
31. Szalai C, Kozma GT, Nagy A et al. Polymorphism in the gene regulatory region of MCP-1 is associated with asthma susceptibility and severity. J Allergy Clin Immunol 2001 108 : 375 381.
32. Qin S, LaRosa G, Campbell JJ et al. Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential. Eur J Immunol 1996 26 : 640 647.
33. Sun YX, Pedersen EA, Shiozawa Y et al. CD26/dipeptidyl peptidase IV regulates prostate cancer metastasis by degrading SDF-1/CXCL12. Clin Exp Metastasis 2008 25 : 765 776.
34. Hoshino M, Aoike N, Takahashi M, Nakamura Y, Nakagawa T. Increased immunoreactivity of stromal cell-derived factor-1 and angiogenesis in asthma. Eur Respir J 2003 21 : 804 809.
35. Ajami K, Pitman MR, Wilson CH et al. Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8. FEBS Lett 2008 582 : 819 825.
36. Farber JM. Mig and IP-10: CXC chemokines that target lymphocytes. J Leukoc Biol 1997 61 : 246 257.
37. Cole KE, Strick CA, Paradis TJ et al. Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J Exp Med 1998 187 : 2009 2021.