Hyperactivity induced by antiphospholipid syndrome serum

Annals of the New York Academy of Sciences

Volumn 1173, Issue , 2009, Pages 422-426

  Menachem, Assaf ^a   Chapman, Joab ^a   Katzav, Aviva ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Animal model; Antiphospholipid syndrome; Behavior; Hyperactivity

Indexed keywords

IMMUNOGLOBULIN G; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPHOSPHOLIPID SYNDROME; ANXIETY; BAGG ALBINO MOUSE; CONFERENCE PAPER; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; FEMALE; HUMAN; HYPERACTIVITY; LOCOMOTION; MOUSE; NONHUMAN; REARING; SERUM; TASK PERFORMANCE;

ANIMALIA; MUS;

EID: 69949122492     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.04876.x     Document Type: Conference Paper

References (21)

1. Rand, J.H. 2002. Molecular pathogenesis of the an-tiphospholipid syndrome. Circ. Res. 90: 29-37.
2. Ferreira, S., D.P. D'Cruz & G.R. Hughes. 2005. Multiple sclerosis, neuropsychiatric lupus and antiphos-pholipid syndrome: where do we stand? Rheumatology (Oxford) 44: 434-442.
3. Roubey, R.A. & M. Hoffman. 1997. From antiphos-pholipid syndrome to antibody-mediated thrombosis. Lancet 350: 1491-1493.
4. Durrani, O.M., C. Gordon & P.I. Murray. 2002. Primary anti-phospholipid antibody syndrome (APS): current concepts. Surv. Ophthalmol. 47: 215-238.
5. Brey, R.L. et al. 2003. Stroke and the antiphospho-lipid syndrome: consensus meeting Taormina 2002. Lupus 12: 508-513.
6. Ruiz-Irastorza, G., M.A. Khamashta & G.R. Hughes. 2002. Hughes syndrome crosses boundaries. Autoimmun. Rev. 1: 43-48.
7. Caronti, B. et al. 1998. Anti-beta 2-glycoprotein I antibodies bind to central nervous system. J. Neurol. Sci. 156: 211-219.
8. Chapman, J. et al. 1999. Antiphospholipid antibodies permeabilize and depolarize brain synaptoneuro-somes. Lupus 8: 127-133.
9. Katzav, A. et al. 2006. Genetic and immunologi-cal factors interact in a mouse model of CNS an-tiphospholipid syndrome. Behav. Brain Res. 169: 289-293.
10. Katzav, A. et al. 2001. Hyperactivity in a mouse model of the antiphospholipid syndrome. Lupus 10: 496-499.
11. Shoenfeld, Y. et al. 2003. Neuronal-binding antibodies from patients with antiphospholipid syndrome induce cognitive deficits following intrathecal passive transfer. Lupus 12: 436-442.
12. Shrot, S. et al. 2002. Behavioral and cognitive deficits occur only after prolonged exposure of mice to antiphospholipid antibodies. Lupus 11: 736-743.
13. Katzav, A. et al. 2007. Induction of autoimmune depression in mice by anti-ribosomal P antibodies via the limbic system. Arthritis Rheum. 56: 938-948.
14. Huang, Q.J. et al. 2004. Brain IL-1β was involved in reserpine-induced behavioral depression in rats. Acta Pharmacol. Sin. 25: 293-296.
15. Koo, J.W. & R.S. Duman. 2008. IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc. Natl. Acad. Sci. USA 105: 751-756.
16. Song, C. 2002. The effect of thymectomy and IL-1 on memory: implications for the relationship between immunity and depression. Brain Behav. Immun. 16: 557-568.
17. Hughes, G.R. 2008. Hughes Syndrome (the an-tiphospholipid syndrome): ten clinical lessons. Autoim-mun. Rev. 7: 262-266.
18. Katzav A. et al. 2008. Anti-P ribosomal antibodies induce defect in smell capability in a model of CNS-SLE (depression). J. Autoimmun. 31: 393-398.
19. Muscal E. & B.L. Myones. 2007. The role of autoantibodies in pediatric neuropsychiatric systemic lupus erythematosus. Autoimmun. Rev. 6: 215-217.
20. Shoenfeld, Y. 2007. To smell autoimmunity: anti-Pribosomal autoantibodies, depression, and the olfactory system. J. Autoimmun. 28: 165-169
21. Stojanovich, L. et al. 2007. Psychiatric manifestations in systemic lupus erythematosus. Autoimmun. Rev. 6: 421-426.