Chimeric IgG4 PR3-ANCA induces selective inflammatory responses from neutrophils through engagement of Fcγ receptors

Immunology

Volumn 128, Issue 2, 2009, Pages 236-244

  Hussain, Abdullah ^a   Pankhurst, Tanya ^a   Goodall, Margaret ^a   Colman, Rachel ^a   Jefferis, Royston ^a   Savage, Caroline O S ^a   Williams, Julie M ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Anti neutrophil cytoplasmic autoantibody; Immunoglobulin; Neutrophils; Subclass; Vasculitis

Indexed keywords

ANTIBODY; BLOCKING ANTIBODY; CHIMERIC ANTIBODY; CYTOCHROME C; FC RECEPTOR; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G4; INTERLEUKIN 8; MONOCLONAL ANTIBODY; MYELOBLASTIN; NEUTROPHIL CYTOPLASMIC ANTIBODY; PROTEINASE 3 ANTIBODY; RECOMBINANT ANTIBODY; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIGEN RECOGNITION; ARTICLE; CELL ADHESION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEGRANULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INFLAMMATION; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RESPIRATORY BURST; SMALL VESSEL VASCULITIS;

ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY-ASSOCIATED VASCULITIS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; CELL ADHESION; CELL DEGRANULATION; CELLS, CULTURED; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-8; MYELOBLASTIN; NEUTROPHIL ACTIVATION; NEUTROPHILS; RECEPTORS, IGG; RECOMBINANT FUSION PROTEINS; RESPIRATORY BURST;

EID: 69949119758     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03108.x     Document Type: Article

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