Stimulant treatment of ADHD and risk of sudden death in children

American Journal of Psychiatry

Volumn 166, Issue 9, 2009, Pages 955-957

  Vitiello, Benedetto ^a   Kenneth, Towbin ^b  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL STIMULANT AGENT;

ATTENTION DEFICIT DISORDER; AUTOPSY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR EFFECT; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CHILD; CLINICAL ASSESSMENT; COMPARATIVE STUDY; DIAGNOSTIC ACCURACY; DRUG INFORMATION; DRUG USE; EDITORIAL; ELECTROCARDIOGRAM; FAMILY HISTORY; HIGH RISK BEHAVIOR; HUMAN; INCIDENCE; INTERVIEW; MEDICAL DECISION MAKING; PRACTICE GUIDELINE; PRESCRIPTION; PRIORITY JOURNAL; QT PROLONGATION; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; RISK FACTOR; RISK REDUCTION; SAMPLE SIZE; SUBSTANCE ABUSE; SUDDEN DEATH; TOXICOLOGY; TRAFFIC ACCIDENT; TREATMENT CONTRAINDICATION; WOLFF PARKINSON WHITE SYNDROME;

ADOLESCENT; ADULT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; CHILD; DEATH, SUDDEN; HUMANS; RISK ASSESSMENT; RISK FACTORS; SUBSTANCE-RELATED DISORDERS; UNITED STATES;

EID: 69949103033     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2009.09050619     Document Type: Editorial

References (14)

1. The MTA Cooperative Group: A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder (ADHD). Arch Gen Psychiatry 1999; 56:1073-1086
2. Van der Oord S, Prins PJ, Oosterlaan J, Emmelkamp PM: Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a meta-analysis. Clin Psychol Rev 2008; 28:783-800
3. Nissen SE: ADHD drugs and cardiovascular risk. N Engl J Med 2006; 354:1445-1448
4. Mc Neil Pharmaceuticals: Product label for Concerta, 2007. Available at: http://www.fda.gov/cder/foi/label/2007/021121s014lbl.pdf (accessed May 5, 2009)
5. Perrin JM, Friedman RA, Knilans TK; Black Box Working Group; Section on Cardiology and Cardiac Surgery: Cardiovascular monitoring and stimulant drugs for attention-deficit/hyperactivity disorder. Pediatrics 2008; 122:451-453
6. Towbin K: Paying attention to stimulants: height, weight, and cardiovascular monitoring in clinical practice. J Am Acad Child Adolesc Psychiatry 2008; 47:977-980
7. Vetter VL, Elia J, Erickson C, Erickson C, Berger S, Blum N, Uzark K, Webb CL: Cardiovascular monitoring of children and adolescents with heart disease receiving stimulant drugs: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young Congenital Cardiac Defects Committee and the Council On Cardiovascular Nursing. Circulation 2008; 117:2407-2423 (Pubitemid 351653546)
8. Gould MS, Walsh BT, Munfakh JL, Kleinman M, Duan N, Olfson M, Greenhill L, Cooper T Sudden death and use of stimulant medications in youths. Am J Psychiatry 2009; 166:992-1001
9. Horwitz RI, Feinstein AR: Methodologic standards and contradictory results in case-control research. Am J Med 1979; 66:556-564 (Pubitemid 9146567)
10. Winterstein AG, Gerhard T, Shuster J, Johnson M, Zito JM, Saidi A: Cardiac safety of central nervous system stimulants in children and adolescents with attention-deficit/hyperactivity disorder. Pediatrics 2007; 120:1494-1501 (Pubitemid 350223669)
11. Angold A, Erkanli A, Egger HL, Costello EJ: Stimulant treatment for children: a community perspective. J Am Acad Child Adolesc Psychiatry 2000; 39:975-984 (Pubitemid 30639785)
12. Pastor PN, Reuben CA: Diagnosed attention deficit hyperactivity disorder and learning disability: United States, 2004-2006. Hyattsville, Md, National Center for Health Statistics, Vital Health Statistics Series 10, number 237, 2008
13. Wilens TE, Adler LA, Adams J, Sgambati S, Rotrosen J, Sawtelle R, Utzinger L, Fusillo S: Misuse and diversion of stimulants prescribed for ADHD: a systematic review of the literature. J Am Acad Child Adolesc Psychiatry 2008; 47:21-31
14. Greely H, Sahakian B, Harris J, Kessler RC, Gazzaniga M, Campbell P, Farah MJ: Towards responsible use of cognitive-enhancing drugs in the healthy. Nature 2008; 456:702-705