메뉴 건너뛰기




Volumn 120, Issue 6, 2007, Pages

Cardiac safety of central nervous system stimulants in children and adolescents with attention-deficit/hyperactivity disorder

Author keywords

Attention deficit disorder; Central nervous system stimulants; Child and adolescent mental health; Pharmacoepidemiology; Psychopharmacology

Indexed keywords

AMPHETAMINE; ANTIDEPRESSANT AGENT; ATOMOXETINE; BRONCHODILATING AGENT; CENTRAL STIMULANT AGENT; METHYLPHENIDATE; MONOAMINE OXIDASE INHIBITOR; NEUROLEPTIC AGENT; PEMOLINE;

EID: 36849078855     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2007-0675     Document Type: Article
Times cited : (109)

References (33)
  • 1
    • 33645507718 scopus 로고    scopus 로고
    • ADHD drugs and cardiovascular risk
    • Nissen SE, ADHD drugs and cardiovascular risk. N Engl J Med. 2006;354:1445-1448
    • (2006) N Engl J Med , vol.354 , pp. 1445-1448
    • Nissen, S.E.1
  • 3
    • 0034700436 scopus 로고    scopus 로고
    • Phenylpropanolamine and the risk of hemorrhagic stroke
    • Kernan WN, Viscoli CM, Brass LM, et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med. 2000;343:1826-1832
    • (2000) N Engl J Med , vol.343 , pp. 1826-1832
    • Kernan, W.N.1    Viscoli, C.M.2    Brass, L.M.3
  • 4
    • 33646096456 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder
    • Biederman J, Mick E, Surman C, et al. A randomized, placebo-controlled trial of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder. Biol Psychiatry. 2006;59:829-835
    • (2006) Biol Psychiatry , vol.59 , pp. 829-835
    • Biederman, J.1    Mick, E.2    Surman, C.3
  • 5
    • 29444460330 scopus 로고    scopus 로고
    • Long-term cardiovascular effects of mixed amphetamine salts extended release in adults with ADHD
    • Weisler RH, Biederman J, Spencer TJ, et al. Long-term cardiovascular effects of mixed amphetamine salts extended release in adults with ADHD. CNS Spectr. 2005;10(12 suppl 20):35-43
    • (2005) CNS Spectr , vol.10 , Issue.12 SUPPL. 20 , pp. 35-43
    • Weisler, R.H.1    Biederman, J.2    Spencer, T.J.3
  • 6
    • 29944434794 scopus 로고    scopus 로고
    • Effect of stimulants on 24-h ambulatory blood pressure in children with ADHD: A double-blind, randomized, cross-over trial
    • Samuels JA, Franco K, Wan F, et al. Effect of stimulants on 24-h ambulatory blood pressure in children with ADHD: a double-blind, randomized, cross-over trial. Pediatr Nephrol. 2006;21:92-95
    • (2006) Pediatr Nephrol , vol.21 , pp. 92-95
    • Samuels, J.A.1    Franco, K.2    Wan, F.3
  • 7
    • 0036020160 scopus 로고    scopus 로고
    • 24-hour ambulatory blood pressure monitoring in male children receiving stimulant therapy
    • Stowe CD, Gardner SF, Gist CC, et al. 24-hour ambulatory blood pressure monitoring in male children receiving stimulant therapy. Ann Pharmacother. 2002;36:1142-1149
    • (2002) Ann Pharmacother , vol.36 , pp. 1142-1149
    • Stowe, C.D.1    Gardner, S.F.2    Gist, C.C.3
  • 9
    • 20044387015 scopus 로고    scopus 로고
    • Blood pressure changes associated with medication treatment of adults with ADHD
    • Wilens TE, Hammerness PG, Biederman J, et al. Blood pressure changes associated with medication treatment of adults with ADHD. J Clin Psychiatry. 2005;66:253-259
    • (2005) J Clin Psychiatry , vol.66 , pp. 253-259
    • Wilens, T.E.1    Hammerness, P.G.2    Biederman, J.3
  • 11
    • 27744601191 scopus 로고    scopus 로고
    • Treatment of attention-deficit/ hyperactivity disorder: Overview of the evidence
    • Available at
    • Brown RT, Amler RW, Freeman WS, et al. Treatment of attention-deficit/ hyperactivity disorder: overview of the evidence. Pediatrics. 2005;115(6). Available at: www.pediatrics.org/cgi/content/full/115/6/e749
    • (2005) Pediatrics , vol.115 , Issue.6
    • Brown, R.T.1    Amler, R.W.2    Freeman, W.S.3
  • 13
    • 36849093816 scopus 로고    scopus 로고
    • and Drug Administration, Center for Drug Evaluation and Research, Available at:, Accessed October 26
    • US Food and Drug Administration, Center for Drug Evaluation and Research. Alert for health professionals: Adderall and Adderall XR (amphetamine). Available at: www.fda.gov/cder/drug/InfoSheets/HCP/adderalHCP.htm. Accessed October 26, 2006
    • (2006) Alert for health professionals: Adderall and Adderall XR (amphetamine)
    • Food, U.S.1
  • 14
    • 33749053231 scopus 로고    scopus 로고
    • Treatment of ADHD with stimulant medications: Response to Nissen perspective in the New England Journal of Medicine
    • Biederman J, Spencer TJ, Wilens TE, Prince JB, Faraone SV. Treatment of ADHD with stimulant medications: response to Nissen perspective in the New England Journal of Medicine. J Am Acad Child Adolesc Psychiatry. 2006;45:1147-1150
    • (2006) J Am Acad Child Adolesc Psychiatry , vol.45 , pp. 1147-1150
    • Biederman, J.1    Spencer, T.J.2    Wilens, T.E.3    Prince, J.B.4    Faraone, S.V.5
  • 15
    • 33846913525 scopus 로고    scopus 로고
    • Stimulant-drug therapy for attention-deficit disorder (with or without hyperactivity) and sudden cardiac death
    • Knight M. Stimulant-drug therapy for attention-deficit disorder (with or without hyperactivity) and sudden cardiac death. Pediatrics. 2007;119:154-155
    • (2007) Pediatrics , vol.119 , pp. 154-155
    • Knight, M.1
  • 16
    • 24144481900 scopus 로고    scopus 로고
    • Mental health in the United States: Prevalence of diagnosis and medication treatment for attention-deficit/hyperactivity disorder - United States, 2003
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Mental health in the United States: prevalence of diagnosis and medication treatment for attention-deficit/hyperactivity disorder - United States, 2003. MMWR Morb Mortal Wkly Rep. 2005;54:842-847
    • (2005) MMWR Morb Mortal Wkly Rep , vol.54 , pp. 842-847
  • 17
    • 36849074599 scopus 로고    scopus 로고
    • Winterstein AG, Gerhard T, Shuster J, Zito JM, Johnson M, Liu H, Saidi A. Utilization of pharmacological treatment in youths with attention-deficit/ hyperactivity disorder in Florida Medicaid 1995-2004. Ann Pharmacother. In press.
    • Winterstein AG, Gerhard T, Shuster J, Zito JM, Johnson M, Liu H, Saidi A. Utilization of pharmacological treatment in youths with attention-deficit/ hyperactivity disorder in Florida Medicaid 1995-2004. Ann Pharmacother. In press.
  • 18
    • 0142157169 scopus 로고    scopus 로고
    • Evaluating medication effects outside of clinical trials: New-user designs
    • Ray WA. Evaluating medication effects outside of clinical trials: new-user designs. Am J Epidemiol. 2003;158:915-920
    • (2003) Am J Epidemiol , vol.158 , pp. 915-920
    • Ray, W.A.1
  • 19
    • 28544432238 scopus 로고    scopus 로고
    • National Hospital Discharge Survey: 2002 annual summary with detailed diagnosis and procedure data. National Center for Health Statistics
    • Kozak LJ, Owings MF, Hall MJ. National Hospital Discharge Survey: 2002 annual summary with detailed diagnosis and procedure data. National Center for Health Statistics. Vital Health Stat 13. 2005;(158):1-199.
    • (2005) Vital Health Stat 13 , vol.158 , pp. 1-199
    • Kozak, L.J.1    Owings, M.F.2    Hall, M.J.3
  • 21
    • 0027207296 scopus 로고
    • Fixing the number of events in large comparative trials with low event rates: A binomial approach
    • Shuster, JJ. Fixing the number of events in large comparative trials with low event rates: a binomial approach. Control Clin Trials. 1993;14:198-208
    • (1993) Control Clin Trials , vol.14 , pp. 198-208
    • Shuster, J.J.1
  • 22
    • 0344628597 scopus 로고    scopus 로고
    • Heart rate and QT interval variability: Abnormal alpha-2 adrenergic function in patients with panic disorder
    • Yeragani VK, Tancer M, Uhde T. Heart rate and QT interval variability: abnormal alpha-2 adrenergic function in patients with panic disorder. Psychiatry Res. 2003;121:185-196
    • (2003) Psychiatry Res , vol.121 , pp. 185-196
    • Yeragani, V.K.1    Tancer, M.2    Uhde, T.3
  • 23
    • 0035086870 scopus 로고    scopus 로고
    • Yeragani VK, Rao KA, Pohl R, Jampala VC, Balon R. Heart rate and QT variability in children with anxiety disorders: a preliminary report [published correction appears in Depress Anxiety. 2001;13:198]. Depress Anxiety. 2001;13:72-77
    • Yeragani VK, Rao KA, Pohl R, Jampala VC, Balon R. Heart rate and QT variability in children with anxiety disorders: a preliminary report [published correction appears in Depress Anxiety. 2001;13:198]. Depress Anxiety. 2001;13:72-77
  • 24
    • 0041423675 scopus 로고    scopus 로고
    • Lynch P, Galbraith KM. Panic in the emergency room. Can J Psychiatry. 2003;48:361-366
    • Lynch P, Galbraith KM. Panic in the emergency room. Can J Psychiatry. 2003;48:361-366
  • 25
    • 0030271808 scopus 로고    scopus 로고
    • Panic disorder in emergency department chest pain patients: Prevalence, comorbidity, suicidal ideation, and physician recognition
    • Fleet RP, Dupuis G, Marchand A, et al. Panic disorder in emergency department chest pain patients: prevalence, comorbidity, suicidal ideation, and physician recognition. Am J Med. 1996;101:371-380
    • (1996) Am J Med , vol.101 , pp. 371-380
    • Fleet, R.P.1    Dupuis, G.2    Marchand, A.3
  • 26
    • 0005818956 scopus 로고    scopus 로고
    • The contribution of epidemiology to the study of drug uses and effects
    • Hartzema AG, Porta M, Tilson HH, eds, 3rd ed. Cincinnati, OH. Harvey Whitney Books;
    • Porta M, Hartzema AG, Tilson HH. The contribution of epidemiology to the study of drug uses and effects. In: Hartzema AG, Porta M, Tilson HH, eds. Pharmacoepidemiology: An Introduction. 3rd ed. Cincinnati, OH. Harvey Whitney Books; 1998
    • (1998) Pharmacoepidemiology: An Introduction
    • Porta, M.1    Hartzema, A.G.2    Tilson, H.H.3
  • 27
    • 0343198955 scopus 로고    scopus 로고
    • Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 1996
    • Schappert SM. Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 1996. Vital Health Stat 13. 1998;(134):1-37
    • (1998) Vital Health Stat 13 , vol.134 , pp. 1-37
    • Schappert, S.M.1
  • 28
    • 36849028494 scopus 로고    scopus 로고
    • Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Drug Abuse Warning Network: Development of a New Design (Methodology Report). Rockville, MD: Substance Abuse and Mental Health Services Administration; 2002. DHHS publication (SMA) 02-3754. 2002 DAWN Series M-4
    • Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Drug Abuse Warning Network: Development of a New Design (Methodology Report). Rockville, MD: Substance Abuse and Mental Health Services Administration; 2002. DHHS publication (SMA) 02-3754. 2002 DAWN Series M-4
  • 29
    • 33646885494 scopus 로고    scopus 로고
    • Stimulant medications and attention deficit-hyperactivity disorder
    • Cohen AL, Jhung MA, Budnitz DS. Stimulant medications and attention deficit-hyperactivity disorder. N Engl J Med. 2006;354:2294-2295
    • (2006) N Engl J Med , vol.354 , pp. 2294-2295
    • Cohen, A.L.1    Jhung, M.A.2    Budnitz, D.S.3
  • 30
    • 36849055921 scopus 로고    scopus 로고
    • Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Drug Abuse Warning Network, 2004: National Estimates of Drug-Related Emergency Department Visits. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2006. DHHS publication (SMA) 06-4143, DAWN Series D-28
    • Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Drug Abuse Warning Network, 2004: National Estimates of Drug-Related Emergency Department Visits. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2006. DHHS publication (SMA) 06-4143, DAWN Series D-28
  • 31
    • 70349255981 scopus 로고    scopus 로고
    • Emergency department visits involving ADHD stimulant medications
    • Substance Abuse and Mental Health Services Administration, Office of Applied Studies, 2006; 29, Available at:, Accessed November 30
    • Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Emergency department visits involving ADHD stimulant medications. The New Dawn Report. 2006; (29). Available at: https://dawninfo.samhsa.gov/files/TNDR09ADHDmedsForHtml.pdf. Accessed November 30, 2006
    • (2006) The New Dawn Report
  • 32
    • 42649146003 scopus 로고    scopus 로고
    • FDA directs ADHD drug manufacturers to notify patients about cardiovascular adverse events and psychiatric adverse events
    • and Drug Administration, Available at:, Accessed March 1, 2007
    • US Food and Drug Administration. FDA News. FDA directs ADHD drug manufacturers to notify patients about cardiovascular adverse events and psychiatric adverse events. Available at: www.fda.gov/bbs/topics/NEWS/2007/ NEW01568.html. Accessed March 1, 2007.
    • FDA News
    • Food, U.S.1
  • 33
    • 25444497043 scopus 로고    scopus 로고
    • Cardiovascular and Renal Drugs Advisory Committee. Report from the Cardiovascular and Renal Drugs Advisory Committee: US Food and Drug Administration: June 15-16, 2005; Gaithersburg, Md
    • Nissen SE; Cardiovascular and Renal Drugs Advisory Committee. Report from the Cardiovascular and Renal Drugs Advisory Committee: US Food and Drug Administration: June 15-16, 2005; Gaithersburg, Md. Circulation. 2005;112:2043-2046
    • (2005) Circulation , vol.112 , pp. 2043-2046
    • Nissen, S.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.