Another potential marker linking gender and cardiac mortality: PAPP-A - A new marker in risk stratification for women presenting with chest pain

Clinica Chimica Acta

Volumn 408, Issue 1-2, 2009, Pages 139-140

  Kavsak, Peter A ^a   Henderson, Matthew ^a   Ko, Dennis T ^b   Wang, Xuesong ^b   MacRae, Andrew R ^c   Jaffe, Allan S ^d  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF MANITOBA   (Canada)

^d MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOCHEMICAL MARKER; C REACTIVE PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPIDERMAL GROWTH FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PADGEM PROTEIN; PREGNANCY ASSOCIATED PLASMA PROTEIN A; TROPONIN I; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; HAZARD RATIO; HEART DEATH; HIGH RISK PATIENT; HUMAN; KAPLAN MEIER METHOD; LETTER; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROTEIN BLOOD LEVEL; RISK ASSESSMENT; SEX DIFFERENCE; THORAX PAIN;

BIOLOGICAL MARKERS; CHEST PAIN; FEMALE; HEART DISEASES; HUMANS; MALE; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; RISK; SEX DISTRIBUTION;

EID: 69849114046     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2009.07.012     Document Type: Letter

References (7)

1. Clerico A., Fontana M., Vittorini S., and Emdin M. The search for a pathophysiological link between gender, cardiac endocrine function, body mass regulation and cardiac mortality: proposal for a working hypothesis. Clin Chim Acta 405 (2009) 1-7
2. Wiviott S.D., Cannon C.P., Morrow D.A., et al. Differential expression of cardiac biomarkers by gender in patients with unstable angina/non-ST-elevation myocardial infarction: a TACTICS-TIMI 18 (Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy-Thrombolysis In Myocardial Infarction 18) substudy. Circulation 109 (2004) 580-586
3. Eggers K.M., Jaffe A.S., Lind L., Venge P., and Lindahl B. Value of cardiac troponin I cutoff concentrations below the 99th percentile for clinical decision-making. Clin Chem 55 (2009) 85-92
4. Apple F.S., Smith S.W., Pearce L.A., and Murakami M.M. Assessment of the multiple-biomarker approach for diagnosis of myocardial infarction in patients with symptoms suggestive of acute coronary syndrome. Clin Chem 55 (2009) 93-100
5. Kavsak P.A., Ko D.T., Newman A.M., et al. Upstream markers provide for early identification of patients at high risk for myocardial necrosis and adverse outcomes. Clin Chim Acta 387 (2008) 133-138
6. Kavsak P.A., MacRae A.R., Yerna M.J., and Jaffe A.S. Analytical and clinical utility of a next generation, highly sensitive cardiac troponin I assay for early detection of myocardial injury. Clin Chem 55 (2009) 573-577
7. Kavsak P.A., Wang X., Henderson M., Ko D.T., MacRae A.R., and Jaffe A.S. PAPP-A as a marker of increased long-term risk in patients with chest pain. Clin Biochem 42 (2009) 1012-1018