"Upstream markers" provide for early identification of patients at high risk for myocardial necrosis and adverse outcomes

Clinica Chimica Acta

Volumn 387, Issue 1-2, 2008, Pages 133-138

  Kavsak, Peter A ^a   Ko, Dennis T ^b   Newman, Alice M ^b   Palomaki, Glenn E ^c   Lustig, Viliam ^d   MacRae, Andrew R ^d,e   Jaffe, Allan S ^f  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c WOMEN AND INFANTS HOSPITAL   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF MANITOBA   (Canada)

^f MAYO CLINIC   (United States)

Author keywords

Acute coronary syndrome; Biomarker panel; Myocardial necrosis; Outcomes

Indexed keywords

BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; L SELECTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PADGEM PROTEIN; TROPONIN I; TROPONIN T; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; CLINICAL ASSESSMENT; COHORT ANALYSIS; CORONARY ARTERY DISEASE; DEATH; DIAGNOSTIC TEST; DISEASE MARKER; EARLY DIAGNOSIS; EMERGENCY WARD; FEMALE; HEART MUSCLE NECROSIS; HIGH RISK PATIENT; HUMAN; KAPLAN MEIER METHOD; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; SAMPLE SIZE;

AGED; BIOLOGICAL MARKERS; CARDIOMYOPATHIES; COHORT STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); PROGNOSIS; RISK FACTORS;

EID: 35748934502     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2007.09.023     Document Type: Article

References (27)

1. Apple F.S., Wu A.H., Mair J., et al. Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome. Clin Chem 51 (2005) 810-824
2. Jaffe A.S., Babuin L., and Apple F.S. Biomarkers in acute cardiac disease: the present and the future. J Am Coll Cardiol 48 (2006) 1-11
3. Jaffe A.S. Cardiovascular biomarkers: the state of the art in 2006. Clin Chim Acta 381 (2007) 9-13
4. Lindmark E., Diderholm E., Wallentin L., and Siegbahn A. Relationship between interleukin 6 and mortality in patients with unstable coronary artery disease. JAMA 286 (2001) 2107-2113
5. Jernberg T., Lindahl B., Siegbahn A., et al. N-Terminal pro-brain natriuretic peptide in relation to inflammation, myocardial necrosis, and the effect of an invasive strategy in unstable coronary artery disease. J Am Coll Cardiol 42 (2003) 1909-1916
6. Maier W., Altwegg L.A., Corti R., et al. Inflammatory markers at the site of ruptured plaque in acute myocardial infarction: locally increased interleukin-6 and serum amyloid A but decreased C-reactive protein. Circulation 111 (2005) 1355-1361
7. Aukrust P., Berg R.K., Ueland T., et al. Interaction between chemokines and oxidative stress: possible pathogenic role in acute coronary syndromes. J Am Coll Cardiol 37 (2001) 485-491
8. Heeschen C., Dimmeler S., Hamm C.W., Fichtlscherer S., Simoons M.L., and Zeilher A.M. Pregnancy-associated plasma protein-a levels in patients with acute coronary syndromes. J Am Coll Cardiol 45 (2005) 229-237
9. Lee K.W., Lip G.Y., and Blann A.D. Plasma angiopoietin-1, angiopoietin-2, angiopoietin receptor tie-2, and vascular endothelial growth factor levels in acute coronary syndromes. Circulation 110 (2004) 2355-2360
10. de Lemos J.A., Morrow D.A., Sabatine M.S., et al. Association between plasma levels of monocyte chomoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes. Circulation 107 (2003) 690-695
11. Wang J., Zhang S., Jin Y., Qin G., Yu L., and Zhang J. Elevated levels of platelet-monocyte aggregates and related circulating biomarkers in patients with acute coronary syndrome. Int J Cardiol 115 (2007) 361-365
12. Kavsak P.A., MacRae A.R., Lustig V., et al. The impact of the ESC/ACC redefinition of myocardial infarction and new sensitive troponin assays on the frequency of acute myocardial infarction. Am Heart J 152 (2006) 118-125
13. MacRae A.R., Kavsak P.A., Lustig V., et al. Assessing the requirement for the six-hour interval between specimens in the American Heart Association classification of myocardial infarction in epidemiology and clinical research studies. Clin Chem 52 (2006) 812-818
14. Kavsak P.A., Newman A.M., Lustig V., et al. Long-term health outcomes associated with detectable troponin I concentrations. Clin Chem 53 (2007) 220-227
15. Kavsak P.A., MacRae A.R., Newman A.M., et al. Effects of contemporary troponin assay sensitivity on the utility of the early markers myoglobin and CKMB isoforms in evaluating patients with possible acute myocardial infarction. Clin Chim Acta 380 (2007) 213-216
16. Berrahmoune H., Lamont J.V., Herbeth B., Fitzgerald P.S., and Visvikis-Siest S. Biological determinants of reference values for plasma interleukin-8, monocyte chemoattractant protein-1, epidermal growth factor, and vascular endothelial growth factor: results from the STANISLAS Cohort. Clin Chem 52 (2006) 504-510
17. Kenis G., Teunissen C., De Jongh R., Bosmans E., Steinbusch H., and Maes M. Stability of interleukin 6, soluble interleukin 6 receptor, interleukin 10 and CC16 in human serum. Cytokine 19 (2002) 228-235
18. Blankenberg S., McQueen M., Smieja M., et al. Comparative impact of multiple biomarkers and N-terminal pro-brain natriuretic peptide in the context of conventional risk factors for the prediction of recurrent cardiovascular events in the Heart Outcomes Prevention Evaluation (HOPE) Study. Circulation 114 (2006) [201-8 pp.]
19. Kragelund C., Gronning B., Kober L., Hildebrandt P., and Steffensen R. N-Terminal Pro-B-type natriuretic peptide and long-term mortality in stable coronary heart disease. N Engl J Med 352 (2005) 666-675
20. Malik I., Danesh J., Whincup P., et al. Soluble adhesion molecules and prediction of coronary heart disease: a prospective study and meta-analysis. Lancet 358 (2001) 971-976
21. Venge P., Lindahl B., and Wallentin L. New generation cardiac troponin I assay for the access immunoassay system. Clin Chem 47 (2001) 959-961
22. Zethelius B., Johnston N., and Venge P. Troponin I as a predictor of coronary heart disease and mortality in 70-year-old men: a community-based cohort study. Circulation 113 (2006) 1071-1078
23. Apple F.S., Quist H.E., Doyle P.J., Otto A.P., and Murakami M.M. Plasma 99th percentile reference limits for cardiac troponin and creatine kinase MB mass for use with European Society of Cardiology/American College of Cardiology Consensus Recommendations. Clin Chem 49 (2003) 1331-1336
24. Austin P.C., Daly P.A., and Tu J.V. A multicentre study of the coding accuracy of hospital discharge administrative data for patients admitted to cardiac care units in Ontario. Am Heart J 144 (2002) 290-296
25. Tu J.V., Pashos C., Naylor C.D., et al. Use of cardiac procedures and outcomes in elderly patients with myocardial infarction in the United States and Canada. N Engl J Med 336 (1997) 1500-1505
26. Blake G.J., and Ridker P.M. C-reactive protein and other inflammatory risk markers in acute coronary syndromes. J Am Coll Cardiol 41 (2003) 37S-42S
27. Deliargyris E.N., Raymond R.J., Theoharides T.C., Boucher W.S., Tate D.A., and Dehmer G.J. Sites of interleukin-6 release in patients with acute coronary syndrome and in patients with congestive heart failure. Am J Cardiol 86 (2000) 913-918