Assessment of long-term subacute exposure to dimethoate by hair analysis of dialkyl phosphates DMP and DMTP in exposed rabbits: The effects of dose, dose duration and hair colour

Environmental Research

Volumn 109, Issue 7, 2009, Pages 821-829

  Margariti, Maria G ^a   Tsatsakis, Aristidis M ^a  

^a UNIVERSITY OF CRETE   (Greece)

Author keywords

Dialkyl phosphates; Dimethoate; Gas chromatography mass spectrometry; Hair; Organophosphate pesticides

Indexed keywords

ALKANEDIOL DERIVATIVE; DIMETHOATE; DIMETHYL THIOPHOSPHATE; DRINKING WATER; ORGANOPHOSPHATE PESTICIDE; PHOSPHORIC ACID DIMETHYL ESTER; UNCLASSIFIED DRUG;

COLOR; GAS CHROMATOGRAPHY; HAIR; MASS SPECTROMETRY; METABOLITE; ORGANOPHOSPHATE; PESTICIDE RESIDUE; POLLUTION EXPOSURE; SMALL MAMMAL;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; GAS CHROMATOGRAPHY; HAIR ANALYSIS; HAIR COLOR; MASS SPECTROMETRY; METABOLITE; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; RABBIT; VALIDATION PROCESS;

ANIMALS; DIMETHOATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HAIR; HAIR COLOR; INSECTICIDES; ORGANOPHOSPHORUS COMPOUNDS; RABBITS; RANDOM ALLOCATION; THIOPHOSPHORIC ACID ESTERS; WATER POLLUTANTS, CHEMICAL;

ORYCTOLAGUS CUNICULUS;

EID: 69849103549     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2009.07.009     Document Type: Article

References (29)

1. Bielawski D., Ostrea Jr. E., Posecion Jr. N., Corrion M., and Seagraves J. Detection of several classes of pesticides and metabolites in meconium by gas chromatography-mass spectrometry. Chromatographia 62 (2005) 623-629
2. Corrion M.L., Ostrea Jr. E.M., Bielawski D.M., Posecion Jr. N.C., and Seagraves J.J. Detection of prenatal exposure to several classes of environmental toxicants and their metabolites by gas chromatography-mass spectrometry in maternal and umbilical cord blood. J. Chromatogr. B 822 (2005) 221-229
3. Costa L.G., Cole T.B., Vitalone A., and Furlong C.E. Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clin. Chim. Acta 352 (2005) 37-47
4. Covaci A., Hura C., Gheorghe A., Neels H., and Dirtu A.C. Organochlorine contaminants in hair of adolescents from Iassy, Romania. Chemosphere 72 (2008) 16-20
5. Drevenkar V., Štengl B., and Fröbe Z. Microanalysis of dialkylphosphorus metabolites of organophosphorus pesticides in human blood by capillary gas chromatography and by phosphorus-selective and ion trap detection. Anal. Chim. Acta 290 (1994) 277-286
6. Duggan A., Charnley G., Chen W., Chukwudebe A., Hawk R., Krieger R.I., Ross J., and Yarborough C. Di-alkyl phosphate biomonitoring data: assessing cumulative exposure to organophosphate pesticides. Regul. Toxicol. Pharmacol. 37 (2003) 382-395
7. Eddleston M., Eyer P., Worek F., Mohamed F., Senarathna L., von Meyer L., Juszczak E., Hittarage A., Azhar S., Dissanayake W., Sheriff M.H., Szinicz L., Dawson A.H., and Buckley N.A. Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study. Lancet 366 (2005) 1452-1459
8. IPCS (International Programme on Chemical Safety). Environmental Health Criteria 90: Dimethoate (1989), WHO (World Health Organization), Geneva
9. Lacassie E., Marquet P., Gaulier J., Dreyfuss M., and Lachâtre G. Sensitive and specific multiresidue methods for the determination of pesticides of various classes in clinical and forensic toxicology. Forensic Sci. Int. 121 (2001) 116-125
10. Margariti M.G., Tsakalof A.K., and Tsatsakis A.M. Analytical methods of biological monitoring for exposure to pesticides: recent update. Ther. Drug Monit. 29 (2007) 150-163
11. Margariti M.G., and Tsatsakis A.M. Analysis of dialkyl phosphate metabolites in hair using gas chromatography-mass spectrometry: a biomarker of chronic exposure to organophosphate pesticides. Biomarkers 14 (2009) 137-147
12. Mieczkowski T., and Newel R. Statistical examination of hair color as a potential biasing factor in hair analysis. Forensic Sci. Int. 107 (2000) 13-38
13. Olsson A.O., Nguyen J.V., Sadowski M.A., and Barr D.B. A liquid chromatography/electrospray ionization-tandem mass spectrometry method for quantification of specific organophosphorus pesticide biomarkers in human urine. Anal. Bioanal. Chem. 376 (2003) 808-815
14. Ostrea Jr. E.M., Villanueva-Uy E., Bielawski D.M., Posecion Jr. N.C., Corrion M.L., Jin Y., Janisse J.J., and Ager J.W. Maternal hair-an appropriate matrix for detecting maternal exposure to pesticides during pregnancy. Environ. Res. 101 (2006) 312-322
15. Posecion Jr. N., Ostrea Jr. E., Bielawski D., Corrion M., Seagraves J., and Jin Y. Detection of exposure to environmental pesticides during pregnancy by the analysis of maternal hair using GC-MS. Chromatographia 64 (2006) 681-687
16. Richardson E.R., and Seiber J.N. Gas chromatographic determination of organophosphorus insecticides and their dialkyl phosphate metabolites in liver and kidney samples. J. Agric. Food Chem. 41 (1993) 416-422
17. Rollins D.E., Wilkins D.G., Krueger G.G., Augsburger M.P., Mizuno A., O'Neal C., Borges C.R., and Slawson M.H. The effect of hair color on the incorporation of codeine into human hair. J. Anal. Toxicol. 27 (2003) 545-551
18. Slawson M.H., Wilkins D.G., and Rollins D.E. The incorporation of drugs into hair: relationship of hair color and melanin concentration to phencyclidine incorporation. J. Anal. Toxicol. 22 (1998) 406-413
19. Tsatsakis A.M., Tutudaki M.I., Tzatzarakis M.N., Psaroudakis K., Dolapsakis G.P., and Michalodimitrakis M.N. Pesticide deposition in hair: preliminary results of a model study of methomyl incorporation into rabbit hair. Vet. Hum. Toxicol. 40 (1998) 200-203
20. Tsatsakis A.M., Psillakis T., Stefis A., Assithianakis P., Vlahonikolis I.G., Michalodimitrakis M.N., and Helidonis E. Determination of phenytoin in sections of head hair: a preliminary study to evaluate the history of drug use. Boll. Chim. Farm. 137 (1998) 459-466
21. Tsatsakis A., and Tutudaki M. Progress in pesticide and POPs hair analysis for the assessment of exposure. Forensic Sci. Int. 145 (2004) 195-199
22. Tsatsakis A.M., Tzatzarakis M.N., and Tutudaki M. Pesticide levels in head hair samples of Cretan population as an indicator of present and past exposure. Forensic Sci. Int. 176 (2008) 67-71
23. Tsoutsi C., Konstantinou I., Hela D., and Albanis T. Screening method for organophosphorus insecticides and their metabolites in olive oil samples based on headspace solid-phase microextraction coupled with gas chromatography. Anal. Chim. Acta 573-574 (2006) 216-222
24. Tutudaki M., Tsakalof A.K., and Tsatsakis A.M. Hair analysis used to assess chronic exposure to the organophosphate diazinon: a model study with rabbits. Hum. Exp. Toxicol. 22 (2003) 159-164
25. Ueyama J., Saito I., Kamijima M., Nakajima T., Gotoh M., Suzuki T., Shibata E., Kondo T., Takagi K., Miyamoto K., Takamatsu J., Hasegawa T., and Takagi K. Simultaneous determination of urinary dialkylphosphate metabolites of organophosphorus pesticides using gas chromatography-mass spectrometry. J. Chromatogr. B 832 (2006) 58-66
26. US EPA (United States Environmental Protection Agency) Office of Pesticide Programs, 2006. Interim reregistration eligibility decision for dimethoate, pp. 1-63.
27. US Public Health Service, 1995. Hazardous substances data bank. Washington, DC.
28. Whyatt R.M., and Barr D.B. Measurement of organophosphate metabolites in postpartum meconium as a potential biomarker of prenatal exposure: a validation study. Environ. Health Perspect. 109 (2001) 417-420
29. Zhang H., Chai Z., and Sun H. Human hair as a potential biomonitor for assessing persistent organic pollutants. Environ. Int. 33 (2007) 685-693