Aldose reductase inhibitor counteracts the attenuated adhesion of human corneal epithelial cells induced by high glucose through modulation of MMP-10 expression

Diabetes Research and Clinical Practice

Volumn 86, Issue 1, 2009, Pages 16-23

  Tomomatsu, Takeshi ^a   Takamura, Yoshihiro ^a   Kubo, Eri ^a   Akagi, Yoshio ^a  

^a UNIVERSITY OF FUKUI   (Japan)

Author keywords

Aldose reductase; Aldose reductase inhibitor; Diabetic keratoepitheliopathy; Human corneal epithelial cell; Matrix metalloproteinase 10

Indexed keywords

ALDOSE REDUCTASE INHIBITOR; FIDARESTAT; GLUCOSE; POLYOL; STROMELYSIN 2; VERY LATE ACTIVATION ANTIGEN 3;

ARTICLE; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; CORNEA EPITHELIUM; CULTURE MEDIUM; DRUG MECHANISM; ENZYME ACTIVITY; EPITHELIUM CELL; GAS CHROMATOGRAPHY; GENE EXPRESSION REGULATION; GLUCOSE INTAKE; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALDEHYDE REDUCTASE; BLOTTING, WESTERN; CELL ADHESION; CELLS, CULTURED; ENZYME INHIBITORS; EPITHELIAL CELLS; EPITHELIUM, CORNEAL; GLUCOSE; HUMANS; INTEGRIN ALPHA3BETA1; MATRIX METALLOPROTEINASE 10; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWEETENING AGENTS;

EID: 69849096829     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2009.07.007     Document Type: Article

References (44)

1. Chikama T., Wakuta M., Liu Y., and Nishida T. Deviated mechanism of wound healing in diabetic corneas. Cornea 26 (2007) 75-81
2. Zagon I.S., Klocek M.S., Sassani J.W., and McLaughlin P.J. Use of topical insulin to normalize corneal epithelial healing in diabetes mellitus. Arch Ophthalmol. 125 (2007) 1082-1088
3. Kaji Y. Prevention of diabetic keratopathy. Br. J. Ophthalmol. 89 (2005) 254-255
4. Perry H.D., Foulks G.N., Thoft R.A., and Tolentino F.I. Corneal complications after closed vitrectomy through the pars plana. Arch Ophthalmol. 96 (1978) 1401-1403
5. Chung H., Tolentino F.I., Cajita V.N., Acosta J., and Refojo M.F. Reevaluation of corneal complications after closed vitrectomy. Arch Ophthalmol. 106 (1988) 916-919
6. Foulks G.N., Thoft R.A., Perry H.D., and Tolentino F.I. Factors related to corneal epithelial complications after closed vitrectomy in diabetics. Arch Ophthalmol. 97 (1979) 1076-1078
7. Kinoshita J.H., Fukushi S., Kador P., and Merola L.O. Aldose reductase in diabetic complications of the eye. Metabolism 28 (1979) 462-469
8. Cogan D.G., Kinoshita J.H., Kador P.F., Robison G., Datilis M.B., Cobo L.M., et al. Aldose reductase and complications of diabetes. Ann. Int. Med. 101 (1984) 82-91
9. Akagi Y., Yajima Y., Kador P.F., Kuwabara T., and Kinoshita J.H. Localization of aldose reductase in the human eye. Diabetes 33 (1984) 562-566
10. Hallberg C.K., Trocme S.D., and Ansari N.H. Acceleration of corneal wound healing in diabetic rats by the antioxidant trolox. Res. Commun. Mol. Pathol. Pharmacol. 93 (1996) 3-12
11. Schäfer M., and Werner S. Oxidative stress in normal and impaired wound repair. Pharmacol. Res. 58 (2008) 165-171
12. Kaji Y., Usui T., Oshika T., Matsubara M., Yamashita H., Araie M., et al. Advanced glycation end products in diabetic corneas. Invest. Ophthalmol. Vis. Sci. 41 (2000) 362-368
13. Kaji Y., Amano S., Usui T., Suzuki K., Tanaka S., Oshika T., et al. Advanced glycation end products in Descemet's membrane and their effect on corneal endothelial cell. Curr. Eye. Res. 23 (2001) 469-477
14. Sato E., Mori F., Igarashi S., Abiko T., Takeda M., Ishiko S., et al. Corneal advanced glycation end products increase in patients with proliferative diabetic retinopathy. Diabetes Care 24 (2001) 479-482
15. Hosotani H., Ohashi Y., Yamada M., and Tsubota K. Reversal of abnormal corneal epithelial cell morphologic characteristics and reduced corneal sensitivity in diabetic patients by aldose reductase inhibitor, CT-112. Am. J. Ophthalmol. 119 (1995) 288-294
16. Yokoi N., Niiya A., Komuro A., Yokogaki S., Naka H., Awata T., et al. Effects of aldose reductase inhibitor CT-112 on the corneal epithelial barrier of galactose-fed rats. Curr. Eye Res. 16 (1997) 595-599
17. Datiles M.B., Kador P.F., Fukui H.N., Hu T.S., and Kinoshita J.H. Corneal re-epithelialization in galactosemic rats. Invest. Ophthalmol. Vis. Sci. 24 (1983) 563-569
18. Ljubimov A.V., Huang Z.S., Huang G.H., Burgeson R.E., Gullberg D., Miner J.H., et al. Human corneal epithelial basement membrane and integrin alterations in diabetes and diabetic retinopathy. J. Histochem. Cytochem. 46 (1998) 1033-1041
19. Saghizadeh M., Brown D.J., Castellon R., Chwa M., Huang G.H., Ljubimova J.Y., et al. Overexpression of matrix metalloproteinase-10 and matrix metalloproteinase-3 in human diabetic corneas: a possible mechanism of basement membrane and integrin alterations. Am. J. Pathol. 158 (2001) 723-734
20. Kahari V.M., and Saarialho-Kere U. Matrix metalloproteinases and their inhibitors in tumour growth and invasion. Ann. Med. 31 (1999) 34-45
21. Murphy G., and Docherty A.J. The matrix metalloproteinases and their inhibitors. Am. J. Respir. Cell. Mol. Biol. 7 (1992) 120-125
22. Visse R., and Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ. Res. 92 (2003) 827-839
23. Woessner Jr. J.F. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5 (1991) 2145-2154
24. Liotta L.A., Steeg P.S., and Stetler-Stevensen W.G. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64 (1991) 327-336
25. Clark A.F. New discoveries on the roles of matrix metalloproteinases in ocular cell biology and pathology. Invest. Ophthalmol. Vis. Sci. 39 (1998) 2514-2516
26. Di Girolamo N., Wakefield D., and Coroneo M.T. Differential expression of matrix metalloproteinases and their tissue inhibitors at the advancing pterygium head. Invest. Ophthalmol. Vis. Sci. 41 (2000) 4142-4149
27. Fini M.E., Cook J.R., and Mohan R. Proteolytic mechanisms in corneal ulceration and repair. Arch Dermatol. Res. 290 (1998) 12-23
28. Kvanta A., Sarman S., Fagerholm P., Seregard S., and Steen B. Expression of matrix metalloproteinase-2 (MMP-2) and vascular endothelial growth factor (VEGF) in inflammation-associated corneal neovascularization. Exp. Eye Res. 70 (2000) 419-428
29. Kabosova A., Kramerov A.A., Aoki A.M., Murphy G., Zieske J.D., and Ljubimov A.V. Human diabetic corneas preserve wound healing, basement membrane, integrin and MMP-10 differences from normal corneas in organ culture. Exp. Eye Res. 77 (2003) 211-217
30. Takamura Y., Tomomatsu T., Kubo E., Tsuzuki S., and Akagi Y. Role of the polyol pathway in high glucose-induced apoptosis of retinal pericytes and proliferation of endothelial cells. Invest. Ophthalmol. Vis. Sci. 49 (2008) 3216-3223
31. Guerrant G.O., and Moss C.W. Detection by gas chromatography of 3-deoxy-D-manno-2-octulosonic acid and L-glycero-D-manno-heptose in whole cells of Neisseria elongata. J. Clin. Microbiol. 23 (1986) 425-430
32. Bannikov G.A., Karelina T.V., Collier I.E., Marmer B.L., and Goldberg G.I. Substrate binding of gelatinase B induces its enzymatic activity in the presence of intact propeptide. J. Biol. Chem. 277 (2002) 16022-16027
33. Tervo K., Tervo T., van Setten G.B., and Virtanen I. Integrins in human corneal epithelium. Cornea 10 (1991) 461-465
34. Filenius S., Hormia M., Rissanen J., Burgeson R.E., Yamada Y., Araki-Sasaki K., et al. Laminin synthesis and the adhesion characteristics of immortalized human corneal epithelial cells to laminin isoforms. Exp. Eye Res. 72 (2001) 93-103
35. Saghizadeh M., Kramerov A.A., Tajbakhsh J., Aoki A.M., Wang C., Chai N.N., et al. Proteinase and growth factor alterations revealed by gene microarray analysis of human diabetic corneas. Invest. Ophthalmol. Vis. Sci. 46 (2005) 3604-3615
36. Fujita H., Morita I., Takase H., Ohno-Matsui K., and Mochizuki M. Prolonged exposure to high glucose impaired cellular behavior of normal human corneal epithelial cells. Curr. Eye Res. 27 (2003) 197-203
37. McDermott A.M., Kern T.S., and Murphy C.J. The effect of elevated extracellular glucose on migration, adhesion and proliferation of SV40 transformed human corneal epithelial cells. Curr. Eye Res. 17 (1998) 924-932
38. Carter W.G., Ryan M.C., and Gahr P.J. Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes. Cell 65 (1991) 599-610
39. Qin P., and Kurpakus M.A. The role of laminin-5 in TGF alpha/EGF-mediated corneal epithelial cell motility. Exp. Eye Res. 66 (1998) 569-579
40. Rousselle P., and Aumailley M. Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptors. J. Cell. Biol. 125 (1994) 205-214
41. Obrosova I.G., Minchenko A.G., Vasupuram R., White L., Abatan O.I., Kumagai A.K., et al. Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats. Diabetes 52 (2003) 864-871
42. Kubo E., Urakami T., Fatma N., Akagi Y., and Singh D.P. Polyol pathway-dependent osmotic and oxidative stresses in aldose reductase-mediated apoptosis in human lens epithelial cells: role of AOP2. Biochem. Biophys. Res. Commun. 314 (2004) 1050-1056
43. Suzen S., and Buyukbingol E. Recent studies of aldose reductase enzyme inhibition for diabetic complications. Curr. Med. Chem. 10 (2003) 1329-1352
44. Lassen N., Black W.J., Estey T., and Vasiliou V. The role of corneal crystallins in the cellular defense mechanisms against oxidative stress. Semin. Cell. Dev. Biol. 19 (2008) 100-112