Putative novel surface-exposed Streptococcus agalactiae protein frequently expressed by the group B Streptococcus from Zimbabwe

Clinical and Vaccine Immunology

Volumn 16, Issue 9, 2009, Pages 1302-1308

  Mavenyengwa, Rooyen T ^a,b   Maeland, Johan A ^b,d   Moyo, Sylvester R ^c  

^a UNIVERSITY OF ZIMBABWE   (Zimbabwe)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c UNIVERSITY OF SOUTH AFRICA   (South Africa)

^d TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ACID; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; PEPSIN A; PERIODATE; PROTEIN R3; RABBIT ANTISERUM; STREPTOCOCCUS AGALACTIAE PROTEIN; TRYPSIN; UNCLASSIFIED DRUG; Z ANTIGEN;

ANTIGEN DETECTION; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; MOLECULAR WEIGHT; NONHUMAN; OXIDATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SEROTYPE; STREPTOCOCCUS AGALACTIAE; WESTERN BLOTTING; WHOLE CELL; ZIMBABWE;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL PROTEINS; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MEMBRANE PROTEINS; MOLECULAR WEIGHT; RABBITS; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS AGALACTIAE; ZIMBABWE;

EID: 69749117086     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00133-09     Document Type: Article

References (34)

1. Areschoug, T., M. Stålhammar-Carlemalm, C. Larsson, and G. Lindahl. 1999. Group B streptococcal surface proteins as targets for protective antibodies: identification of two novel proteins in strains of serotype V. Infect. Immun. 67:6350-6357.
2. Bevanger, L., and J. A. Maeland. 1977. Type classification of group B streptococci by the fluorescent antibody test. Acta Pathol. Microbiol. Immunol. Scand. Sect. B 85:357-362.
3. Bevanger, L., and J. A. Maeland. 1979. Complete and incomplete Ibc protein fraction in group B streptococci. Acta Pathol. Microbiol. Immunol. Scand. Sect. B 87:51-54.
4. Brodeur, B. R., M. Boyer, I. Charlebois, J. Hamel, F. Couture, C. R. Rioux, and D. Martin. 2000. Identification of group B streptococcal Sip protein, which elicits cross-protective immunity. Infect. Immun. 68:5610-5618.
5. Chmouryguina, I., A. Suvorov, P. Ferrieri, and P. P. Cleary. 1996. Conservation of the C5a peptidase genes in group A and B streptococci. Infect. Immun. 64:2387-2390.
6. Creti, R., F. Fabretti, G. Orefici, and C. von Hunolstein. 2004. Multiplex PCR assay for direct identification of group B streptococcal alpha-protein-like protein genes. J. Clin. Microbiol. 42:1326-1329.
7. Erdogan, S., P. K. Fagan, S. R. Talay, M. Rohde, P. Ferrieri, A. E. Flores, C. A. Guzman, M. J. Walker, and G. S. Chhatwal. 2002. Molecular analysis of group B protective surface protein, a new surface protective antigen of group B streptococci. Infect. Immun. 70:803-811.
8. Flores, A. E., and P. Ferrieri. 1989. Molecular species of R-protein antigens produced by clinical isolates of group B streptococci J. Clin. Microbiol. 27:1050-1054.
9. Gherardi, G., M. Imperi, L. Baldassarri, M. Pataracchia, G. Alfarone, S. Recchia, G. Orefici, G. Dicuonzo, and R. Creti. 2007. Molecular epidemiology and distribution of serotypes, surface proteins, and antibiotic resistance among group B streptococci in Italy. J. Clin. Microbiol. 45:2909-2916.
10. Harrison, L. H., J. A. Elliott, D. M. Dwyer, J. P. Libonati, P. Ferrieri, L. Billmann, and A. Schuchat. 1998. Serotype distribution of invasive group B streptococcal isolates in Maryland: implications for vaccine formulation. J. Infect. Dis. 177:998-1002.
11. Kong, F., S. Gowan, D. Martin, G. James, and G. L. Gilbert. 2002. Molecular profiles of group B streptococcal surface protein antigen genes: relationship to molecular serotypes. J. Clin. Microbiol. 40:620-626.
12. Kvam, A. I., L. Bevanger, and J. A. Maeland. 1999. Properties and distribution of the putative R3 protein of Streptococcus agalactiae. APMIS 107:869-874.
13. Lachenauer, C. S., R. Creti, J. L. Michel, and L. C. Madoff. 2000. Mosaicism in the alpha-like protein genes of group B streptococci. Proc. Natl. Acad. Sci. USA 97:9630-9635.
14. Lachenauer, C. S., D. L. Kasper, J. Shimada, Y. Ichiman, H. Ohtsuka, M. Kaku, L. C. Paoletti, P. Ferrieri, and L. C. Madoff. 1999. Serotypes VI and VIII predominate among group B streptococci isolated from pregnant Japanese women. J. Infect. Dis. 179:1030-1033.
15. Lindahl, G., M. Stålhammar-Carlemalm, and T. Areschoug. 2005. Surface proteins of Streptococcus agalactiae and related proteins in other bacterial pathogens. Clin. Microbiol. Rev. 18:102-127.
16. Madoff, L. C., S. Hori, J. L. Michel, C. J. Baker, and D. L. Kasper. 1991. Phenotypic diversity in the alpha C protein of group B streptococci. Infect. Immun. 59:2638-2644.
17. Maeland, J. A., L. Bevanger, and R. V. Lyng. 2004. Antigenic determinants of alpha-like proteins of Streptococcus agalactiae. Clin. Diagn. Lab. Immunol. 11:1035-1039.
18. Maeland, J. A., L. Bevanger, and R. V. Lyng. 2005. Immunological markers of the R4 protein of Streptococcus agalactiae. Clin. Diagn. Lab. Immunol. 12:1305-1310.
19. Mavenyengwa, R. T., J. A. Maeland, and S. R. Moyo. 2008. Distinctive features of surface-anchored proteins of Streptococcus agalactiae strains from Zimbabwe revealed by PCR and dot blotting. Clin. Vaccine Immunol. 15: 1420-1424.
20. Michel, J. L., L. C. Madoff, K. Olson, D. E. Kling, D. L. Kasper, and F. M. Ausubel. 1992. Large, identical, tandem repeating units in the C protein alpha antigen gene, bca, of group B streptococci. Proc. Natl. Acad. Sci. USA 89:10060-10064.
21. Moyo, S. R., and J. A. Maeland. 2003. Antibodies raised in animals against the Streptococcus agalactiae proteins Cα and R4 and normal human serum antibodies target distinct epitopes. J. Med. Microbiol. 52:379-383.
22. Moyo, S. R., J. A. Maeland, and K. Berg. 2002. Typing of human isolates of Streptococcus agalactiae (group B streptococci; GBS) strains from Zimbabwe. J. Med. Microbiol. 51:595-600.
23. Moyo, S. R., J. A. Maeland, and L. Bevanger. 1999. Comparison of three different methods in monoclonal antibody-based detection of Streptococcus agalactiae serotype markers. APMIS 107:263-269.
24. Persson, E., S. Berg, L. Bevanger, K. Bergh, R. Valsø-Lyng, and B. Trollfors. 2008. Characterisation of invasive group B streptococci based on investigation of surface proteins and genes encoding surface proteins. Clin. Microbiol. Infect. 14:66-73.
25. Schubert, A., K. Zakikhany, M. Schreiner, R. Frank, B. Spellerberg, B. J. Eikmanns, and D. J. Reinscheid. 2002. A fibrinogen receptor from group Streptococcus interacts with fibrinogen by repetitive units with novel ligand binding sites. Mol. Microbiol. 46:557-569.
26. Seifert, K. N., E. E. Adderson, A. A. Whiting, J. F. Bohnsack, P. J. Crowley, and L. J. Brady. 2006. A unique serine-rich repeat protein (Srr-2) and novel surface antigen (ε) associated with a virulent lineage of serotype III Streptococcus agalactiae. Microbiology 152:1029-1040.
27. Slotved, H.-C., F. Kong, L. Lambertsen, S. Sauer, and G. L. Gilbert. 2007. Serotype IX, a proposed new Streptococcus agalactiae serotype. J. Clin. Microbiol. 45:2929-2936.
28. Smith, B. L., A. Flores, J. Dechaine, J. Krepela, A. Bergdall, and P. Ferrieri. 2004. Gene encoding the group B streptococcal protein R4, its presence in clinical reference laboratory isolates & R4 protein pepsin sensitivity. Indian J. Med. Res. 119(Suppl.):213-220.
29. Spellerberg, B., E. Rozdzinski, S. Martin, J. Weber-Heynemann, N. Schnitzler, R. Lütticken, and A. Podbielski. 1999. Lmb, a protein with similarities to the LraI adhesin family, mediates attachment of Streptococcus agalactiae to human laminin. Infect. Immun. 67:871-878.
30. Stålhammar-Carlemalm, M., T. Areschoug, C. Larsson, and G. Lindahl. 2000. Cross-protection between group A and group B streptococci due to cross-reacting surface proteins. J. Infect. Dis. 182:142-149.
31. Wästfelt, M., M. Stålhammar-Carlemalm, A.-M. Delisse, T. Cabezon, and G. Lindahl. 1996. Identification of a family of streptococcal surface proteins with extremely repetitive structure. J. Biol. Chem. 271:18892-18897.
32. Wilkinson, H. W. 1972. Comparison of streptococcal R antigens. Appl. Microbiol. 24:669-670.
33. Yang, H.-H., L. C. Madoff, H.-K. Guttormsen, Y.-D. Liu, and L. C. Paoletti. 2007. Recombinant group B streptococcus beta C protein and a variant with the deletion of its immunoglobulin A-binding site are protective mouse maternal vaccines and effective carriers in conjugate vaccines. Infect. Immun. 75:3455-3461.
34. Yang, H.-H., S. J. Mascuch, L. C. Madoff, and L. C. Paoletti. 2008. Recombinant group B Streptococcus alpha-like protein 3 is an effective immunogen and carrier protein. Clin. Vaccine Immunol. 15:1035-1041.