Hot Electron Capture Dissociation Distinguishes Leucine from Isoleucine in a Novel Hemoglobin Variant, Hb Askew, β54(D5)Val→Ile

Journal of the American Society for Mass Spectrometry

Volumn 20, Issue 9, 2009, Pages 1707-1713

  Williams, Jonathan P ^a   Creese, Andrew J ^b   Roper, David R ^c   Green, Brian N ^d   Cooper, Helen J ^b  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c HAMMERSMITH HOSPITAL   (United Kingdom)

^d MICROMASS UK LTD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; DIRECT ANALYSIS; EFFECTIVE MASS; FOURIER TRANSFORM ION CYCLOTRON RESONANCE; GLOBIN CHAINS; HEMOGLOBINOPATHIES; HOT ELECTRON CAPTURE DISSOCIATIONS; LOW ENERGY COLLISIONS;

AMINATION; AMINES; DISSOCIATION; HEMOGLOBIN; HOT ELECTRONS; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC ACIDS; POSITIVE IONS;

AMINO ACIDS;

HEMOGLOBIN VARIANT; ISOLEUCINE; LEUCINE; VALINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CLINICAL EFFECTIVENESS; CODON; CONTROLLED STUDY; ELECTRON CAPTURE DETECTION; FRAGMENTATION REACTION; GENE MUTATION; HUMAN; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SUBSTITUTION; COMPUTER SIMULATION; ELECTRONS; HEMOGLOBINS; HOT TEMPERATURE; ISOLEUCINE; LEUCINE; MODELS, CHEMICAL; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 69549133494     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2009.05.002     Document Type: Article

References (13)

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