Early detection of colorectal cancer metastasis and relapse by recognizing nonspecific cross-reacting antigen 2 in commercial carcinoembryonic antigen assays

Clinical Chemistry

Volumn 55, Issue 9, 2009, Pages 1747-1748

  Hanada, Hiroyuki ^a,b   Mugii, Satami ^a   Takeoka, Keiko ^a   Maeda, Ikuhiro ^a   Watanabe, Mikio ^b   Hidaka, Yoh ^a   Iwatani, Yoshiori ^b  

^a OSAKA UNIVERSITY HOSPITAL   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; NONSPECIFIC CROSS REACTING ANTIGEN 2; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

BLOOD SAMPLING; CANCER PATIENT; CANCER RELAPSE; COLORECTAL CANCER; CROSS REACTION; DIAGNOSTIC ACCURACY; HUMAN; LETTER; LIVER METASTASIS; SENSITIVITY AND SPECIFICITY; WESTERN BLOTTING;

CARCINOEMBRYONIC ANTIGEN; COLORECTAL NEOPLASMS; EARLY DIAGNOSIS; GENE EXPRESSION REGULATION, NEOPLASTIC; NEOPLASM METASTASIS; RECURRENCE;

EID: 69549098124     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2008.121897     Document Type: Letter

References (4)

1. Boermer OP, Thrane-steen K. Epitope group specificity of six immunoassays for carcinoembryonic antigen. Tumour Biol 1991;12:9-15.
2. Bjerner J, Lebedin Y, Bellanger L, Kuroki M, Shively JE, Varaas T, et al. Protein epitopes in carcinoembryonic antigen. Tumour Biol 2002;23:249-262
3. Börmer OP. Major disagreements between immumoassays of carcinoembryonic antigen may be caused by nonspecific cross-reacting antigen 2 (NCA-2). Clin Chem 1991;37:1736-1739
4. Sturgeon CM, Duffy MJ, Stenman UH, Lilja H, Brunner N, Chan DW, et al. National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers. Clin Chem 2008;54:12 e11-79. (Pubitemid 352777353)