-
1
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
-
Irinotecan Study Group
-
Saltz LB, Cox JV, Blanke C, Rosen LS, Fehrenbacher L, Moore MJ, Maroun JA, Ackland SP, Locker PK, Pirotta N, Elfring GL, Miller LL: Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000; 343: 905-914.
-
(2000)
N Engl J Med
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
Rosen, L.S.4
Fehrenbacher, L.5
Moore, M.J.6
Maroun, J.A.7
Ackland, S.P.8
Locker, P.K.9
Pirotta, N.10
Elfring, G.L.11
Miller, L.L.12
-
2
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, Navarro M, James RD, Karasek P, Jandik P, Iveson T, Carmichael J, Alakl M, Gruia G, Awad L, Rougier P: Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000; 355: 1041-1047.
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
Navarro, M.4
James, R.D.5
Karasek, P.6
Jandik, P.7
Iveson, T.8
Carmichael, J.9
Alakl, M.10
Gruia, G.11
Awad, L.12
Rougier, P.13
-
3
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignard D, Quinaux E, Couteau C, Buyse M, Ganem G, Landi B, Colin P, Louvet C, de Gramont A: FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004; 22: 229-237.
-
(2004)
J Clin Oncol
, vol.22
, pp. 229-237
-
-
Tournigand, C.1
André, T.2
Achille, E.3
Lledo, G.4
Flesh, M.5
Mery-Mignard, D.6
Quinaux, E.7
Couteau, C.8
Buyse, M.9
Ganem, G.10
Landi, B.11
Colin, P.12
Louvet, C.13
De Gramont, A.14
-
4
-
-
24644457747
-
Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico Dell'Italia Meridionale
-
Colucci G, Gebbia V, Paoletti G, Giuliani F, Caruso M, Gebbia N, Carteni G, Agostara B, Pezzella G, Manzione L, Borsellino N, Misino A, Romito S, Durini E, Cordio S, di Seri M, Lopez M, Maiello E, Montemurro S, Cramarossa A, Lorusso V, di Bisceglie M, Chiarenza M, Valerio MR, Guida T, Leonardi V, Pisconti S, Rosati G, Carrozza F, Nettis G, Valdesi M, Filippelli G, Fortunato S, Mancarella S, Brunetti C: Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol 2005; 23: 4866-4875.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4866-4875
-
-
Colucci, G.1
Gebbia, V.2
Paoletti, G.3
Giuliani, F.4
Caruso, M.5
Gebbia, N.6
Carteni, G.7
Agostara, B.8
Pezzella, G.9
Manzione, L.10
Borsellino, N.11
Misino, A.12
Romito, S.13
Durini, E.14
Cordio, S.15
Di Seri, M.16
Lopez, M.17
Maiello, E.18
Montemurro, S.19
Cramarossa, A.20
Lorusso, V.21
Di Bisceglie, M.22
Chiarenza, M.23
Valerio, M.R.24
Guida, T.25
Leonardi, V.26
Pisconti, S.27
Rosati, G.28
Carrozza, F.29
Nettis, G.30
Valdesi, M.31
Filippelli, G.32
Fortunato, S.33
Mancarella, S.34
Brunetti, C.35
more..
-
5
-
-
24644432555
-
Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer
-
European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986
-
Köhne CH, van Cutsem E, Wils J, Bokemeyer C, El-Serafi M, Lutz MP, Lorenz M, Reichardt P, Rückle-Lanz H, Frickhofen N, Fuchs R, Mergenthaler HG, Langenbuch T, Vanhoefer U, Rougier P, Voigtmann R, Müller L, Genicot B, Anak O, Nordlinger B: Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986. J Clin Oncol 2005; 23: 4856-4865.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4856-4865
-
-
Köhne, C.H.1
Van Cutsem, E.2
Wils, J.3
Bokemeyer, C.4
El-Serafi, M.5
Lutz, M.P.6
Lorenz, M.7
Reichardt, P.8
Rückle-Lanz, H.9
Frickhofen, N.10
Fuchs, R.11
Mergenthaler, H.G.12
Langenbuch, T.13
Vanhoefer, U.14
Rougier, P.15
Voigtmann, R.16
Müller, L.17
Genicot, B.18
Anak, O.19
Nordlinger, B.20
more..
-
6
-
-
0344109583
-
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer
-
Meta-Analysis Group in Cancer
-
Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer. Meta-Analysis Group in Cancer. J Clin Oncol 1998; 16: 301-308.
-
(1998)
J Clin Oncol
, vol.16
, pp. 301-308
-
-
-
7
-
-
0029835349
-
Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators
-
Shirasaka T, Shimamato Y, Ohshimo H, Yamaguchi M, Kato T, Yonekura K, Fukushima M: Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs 1996; 7: 548-557.
-
(1996)
Anticancer Drugs
, vol.7
, pp. 548-557
-
-
Shirasaka, T.1
Shimamato, Y.2
Ohshimo, H.3
Yamaguchi, M.4
Kato, T.5
Yonekura, K.6
Fukushima, M.7
-
8
-
-
0034089123
-
Phase II study of S-1, a novel oral fluorophyrimidine derivative, in patients with metastatic colorectal carcinoma
-
S-1 Cooperative Colorectal Carcinoma Study Group.
-
Ohtsu A, Baba H, Sakata Y, Mitachi Y, Horikoshi N, Sugimachi K, Taguchi T: Phase II study of S-1, a novel oral fluorophyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group. Br J Cancer 2000; 83: 141-145.
-
(2000)
Br J Cancer
, vol.83
, pp. 141-145
-
-
Ohtsu, A.1
Baba, H.2
Sakata, Y.3
Mitachi, Y.4
Horikoshi, N.5
Sugimachi, K.6
Taguchi, T.7
-
9
-
-
2442674385
-
Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma
-
Shirao K, Ohtsu A, Takada H, Mitachi Y, Hirakawa K, Horikoshi N, Okamura T, Hirata K, Saitoh S, Isomoto H, Satoh A: Phase II study of oral S-1 for treatment of metastatic colorectal carcinoma. Cancer 2004; 100: 2355-2361.
-
(2004)
Cancer
, vol.100
, pp. 2355-2361
-
-
Shirao, K.1
Ohtsu, A.2
Takada, H.3
Mitachi, Y.4
Hirakawa, K.5
Horikoshi, N.6
Okamura, T.7
Hirata, K.8
Saitoh, S.9
Isomoto, H.10
Satoh, A.11
-
10
-
-
37049025366
-
Phase i study of S-1 combined with irinotecan (CPT-11) in patients with advanced colorectal cancer
-
Tsunoda A, Yasuda N, Nakao K, Narita K, Yamazaki K, Watanabe M, Suzuki N, Kusano M: Phase I study of S-1 combined with irinotecan (CPT-11) in patients with advanced colorectal cancer. Oncology 2007; 72: 58-63.
-
(2007)
Oncology
, vol.72
, pp. 58-63
-
-
Tsunoda, A.1
Yasuda, N.2
Nakao, K.3
Narita, K.4
Yamazaki, K.5
Watanabe, M.6
Suzuki, N.7
Kusano, M.8
-
11
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors
-
Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, Verweij J, van Glabbeke M, van Oosterom AT, Christian MC, Gwyther SG: New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92: 205-216. (Pubitemid 30099779)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.3
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
Wanders, J.4
Kaplan, R.S.5
Rubinstein, L.6
Verweij, J.7
Van Glabbeke, M.8
Van Oosterom, A.T.9
Christian, M.C.10
Gwyther, S.G.11
-
12
-
-
70349549458
-
Phase II study of combination with irinotecan and S-1 (IRIS) for inoperable recurrent advanced colorectal cancer (HGCSG0302): Final analysis (abstract 15112). ASCO Annual Meeting Proceedings
-
Yuki S, Komatsu Y, Iwanaga I, Fukushima H, Kudo M, Tateyama M, Meguro T, Watanabe M, Asaka M, Sakata Y: Phase II study of combination with irinotecan and S-1 (IRIS) for inoperable recurrent advanced colorectal cancer (HGCSG0302): final analysis (abstract 15112). ASCO Annual Meeting Proceedings. J Clin Oncol 2008; 26(suppl 20).
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL. 20
-
-
Yuki, S.1
Komatsu, Y.2
Iwanaga, I.3
Fukushima, H.4
Kudo, M.5
Tateyama, M.6
Meguro, T.7
Watanabe, M.8
Asaka, M.9
Sakata, Y.10
-
13
-
-
33646883433
-
Phase II study of combination therapy with S-1 and irinotecan in patients with advanced colorectal cancer
-
Goto A, Yamada Y, Yasui H, Kato K, Hamaguchi T, Muro K, Shimada Y, Shirao K: Phase II study of combination therapy with S-1 and irinotecan in patients with advanced colorectal cancer. Ann Oncol 2006; 17: 968-973.
-
(2006)
Ann Oncol
, vol.17
, pp. 968-973
-
-
Goto, A.1
Yamada, Y.2
Yasui, H.3
Kato, K.4
Hamaguchi, T.5
Muro, K.6
Shimada, Y.7
Shirao, K.8
-
14
-
-
36048960109
-
Randomized, controlled trial of irinotecal plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C study
-
Fuchs CS, Marshall J, Mitchell E, Wierzbicki R, Ganju V, Jeffery M, Schulz J, Richards D, Soufi-Mahjoubi R, Wang B, Barrueco J: Randomized, controlled trial of irinotecal plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C study. J Clin Oncol 2007; 325: 4779-4786.
-
(2007)
J Clin Oncol
, vol.325
, pp. 4779-4786
-
-
Fuchs, C.S.1
Marshall, J.2
Mitchell, E.3
Wierzbicki, R.4
Ganju, V.5
Jeffery, M.6
Schulz, J.7
Richards, D.8
Soufi-Mahjoubi, R.9
Wang, B.10
Barrueco, J.11
-
15
-
-
34548440297
-
Capecitabine plus 3-weekly irinotecan (XELIRI regimen) as first-line chemotherapy for metastatic colorectal cancer: Phase II trial results
-
Patt TZ, Lee FC, Liebmann JE, Diamandidis D, Eckhardt SG, Javle M, Glen R, Kaiser W, Salvatore J, Bexon A, Lin E: Capecitabine plus 3-weekly irinotecan (XELIRI regimen) as first-line chemotherapy for metastatic colorectal cancer: phase II trial results. Am J Clin Oncol 2007; 30: 350-357.
-
(2007)
Am J Clin Oncol
, vol.30
, pp. 350-357
-
-
Patt, T.Z.1
Lee, F.C.2
Liebmann, J.E.3
Diamandidis, D.4
Eckhardt, S.G.5
Javle, M.6
Glen, R.7
Kaiser, W.8
Salvatore, J.9
Bexon, A.10
Lin, E.11
-
16
-
-
9144255466
-
Randomized multicenter phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma
-
Italian Trials in Medical Oncology (ITMO) Group
-
Bajetta E, di Bartolomeo M, Mariani L, Cassata A, Artale S, Frustaci S, Pinotti G, Bonetti A, Carreca I, Biasco G, Bonaglia L, Marini G, Iannelli A, Cortinovis D, Ferrario E, Beretta E, Lambiase A, Buzzoni R, Italian Trials in Medical Oncology (ITMO) Group: Randomized multicenter phase II trial of two different schedules of irinotecan combined with capecitabine as first-line treatment in metastatic colorectal carcinoma. Cancer 2004; 100: 279-287.
-
(2004)
Cancer
, vol.100
, pp. 279-287
-
-
Bajetta, E.1
Di Bartolomeo, M.2
Mariani, L.3
Cassata, A.4
Artale, S.5
Frustaci, S.6
Pinotti, G.7
Bonetti, A.8
Carreca, I.9
Biasco, G.10
Bonaglia, L.11
Marini, G.12
Iannelli, A.13
Cortinovis, D.14
Ferrario, E.15
Beretta, E.16
Lambiase, A.17
Buzzoni, R.18
-
17
-
-
43049126513
-
Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer: EORTC study 40015
-
Köhne CH, de Greve J, Hartmenn JT, Lang I, Vergauwe P, Becker K, Braumann D, Joosens E, Müller L, Janssens J, Bokemeyer C, Reimer P, Link H, Späth-Schwalbe E, Wilke HJ, Bleiberg H, van den Brande J, Debois M, Bethe U, van Cutsem E: Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer: EORTC study 40015. Ann Oncol 2008; 19: 920-926.
-
(2008)
Ann Oncol
, vol.19
, pp. 920-926
-
-
Köhne, C.H.1
De Greve, J.2
Hartmenn, J.T.3
Lang, I.4
Vergauwe, P.5
Becker, K.6
Braumann, D.7
Joosens, E.8
Müller, L.9
Janssens, J.10
Bokemeyer, C.11
Reimer, P.12
Link, H.13
Späth-Schwalbe, E.14
Wilke, H.J.15
Bleiberg, H.16
Van Den Brande, J.17
Debois, M.18
Bethe, U.19
Van Cutsem, E.20
more..
-
18
-
-
0042009667
-
A phase I/II study of oral uracil/ tegafur (UFT), leucovorin and irinotecan in patients with advanced colorectal cancer
-
Mackay HJ, Hill M, Twelves C, Glasspool R, Price T, Campbell S, Massey A, Macham MA, Uzzel M, Bailey SM, Martin C, Cunningham D: A phase I/II study of oral uracil/ tegafur (UFT), leucovorin and irinotecan in patients with advanced colorectal cancer. Ann Oncol 2003; 14: 1264-1269.
-
(2003)
Ann Oncol
, vol.14
, pp. 1264-1269
-
-
MacKay, H.J.1
Hill, M.2
Twelves, C.3
Glasspool, R.4
Price, T.5
Campbell, S.6
Massey, A.7
MacHam, M.A.8
Uzzel, M.9
Bailey, S.M.10
Martin, C.11
Cunningham, D.12
-
19
-
-
33846821578
-
Uracil/ftorafur/ leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: Results of randomized phase II study
-
Bajetta E, di Bartolomeo M, Buzzoni R, Mariani L, Zilembo N, Ferrario E, Lo Vullo S, Aitini E, Isa L, Barone C, Jacobelli S, Recaldin E, Pinotti G, Iop A: Uracil/ftorafur/ leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: results of randomized phase II study. Br J Cancer 2007; 96: 439-444.
-
(2007)
Br J Cancer
, vol.96
, pp. 439-444
-
-
Bajetta, E.1
Di Bartolomeo, M.2
Buzzoni, R.3
Mariani, L.4
Zilembo, N.5
Ferrario, E.6
Lo Vullo, S.7
Aitini, E.8
Isa, L.9
Barone, C.10
Jacobelli, S.11
Recaldin, E.12
Pinotti, G.13
Iop, A.14
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