Monocytes/macrophages infected with Toxoplasma gondii do not increase co-stimulatory molecules while maintaining their migratory ability

APMIS

Volumn 117, Issue 9, 2009, Pages 672-680

  Seipel, Daniele ^a   Ribeiro Gomes, Flavia Lima ^a   Barcelos, Michelle Willmen ^b   Ramalho, André VillaÇa ^a   Kanashiro, Milton M ^a   Kipnis, Thereza Liberman ^a   Arnholdt, Andrea Cristina Veto ^a,c  

^a UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

^b HOSPITAL GERAL DE FORTALEZA   (Brazil)

^c Campos Dos Goytacazes ^*  (Brazil)

Author keywords

2 integrin; CD80; L selectin; Migration; T. gondii

Indexed keywords

BETA2 INTEGRIN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; L SELECTIN; T6 ANTIGEN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PARASITE; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD14; CELL ADHESION MOLECULES; CELL LINE; CELL MOVEMENT; HLA-DR ANTIGENS; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; TOXOPLASMA; TOXOPLASMOSIS;

EID: 69449103295     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2009.02519.x     Document Type: Article

References (31)

1. Dubey JP, Beattie CP. Toxoplasmosis of Animals and Man. Boca Raton, FL : CRC Press, 1988.
2. Morisaki JH, Henser JE, Sibley LD. Invasion of Toxoplasma gondii occurs by active penetration of the host cell. J Cell Sci 1995 108 : 2457 2464.
3. De Carvalho L, De Souza W. Cytochemical localization of plasma membrane enzyme markers during interiorization of tachyzoites of Toxoplasma gondii by macrophages. J Protozool 1989 36 : 162 170.
4. Gazzinelli RT, Denkers EY, Sher A. Host resistance to Toxoplasma gondii in primary rat CNS cells: differential contribution of neurons, astrocytes and microglial cells for the intracerebral development and stage differentiation. Exp Parasitol 1993 93 : 23 32.
5. Hunter CA, Remington JS. Immunopathogenesis of toxoplasmic encephalitis. J Infect Dis 1994 170 : 1057 1067.
6. Lüder CG, Lang T, Beuerle B, Gross U. Down-regulation of MHC class II molecules and inability to up-regulate class I molecules in murine macrophages after infection with Toxoplasma gondii. Clin Exp Immunol 1998 112 : 308 316.
7. Chao CC, Gekker G, Hu S, Peterson PK. Human microglial defense against Toxoplasma gondii. The role of cytokines. J Immunol 1994 152 : 1246 1252.
8. Luft BJ, Remington JS. Toxoplasmic encephalitis in AIDS. Clin Infect Dis 1992 14 : 211 222.
9. Richards FO Jr., Kovacs JA, Luft BJ. Preventing toxoplasmic encephalitis in persons infected with human immunodeficiency virus. Clin Infect Dis 1995 21 : S49 56.
10. Montoya JG, Remington JS. Management of Toxoplasma gondii infection during pregnancy. Clin Infect Dis 2008 47 : 554 566.
11. Gilbert RE, Freeman K, Lago EG, Bahia-Oliveira LMG, Tan HK, Wallon M, et al. (EMSCOT). Ocular sequelae of congenital toxoplasmosis in Brazil compared with Europe. PLoS Negl Trop Dis 2008 2 : e277.
12. Da Gama LM, Ribeiro-Gomes FL, Guimarães U Jr., Arnholdt ACV. Reduction in adhesiveness to extracellular matrix components, modulation of adhesion molecules and in vivo migration of murine macrophages infected with T. gondii. Microbes Infect 2004 6 : 1287 1296.
13. Courret N, Darche S, Sonigo P, Milon G, Buzoni-Gâtel D, Tardieux I. CD11c and CD11b expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain. Blood 2006 107 : 309 316.
14. Lambert H, Hitzinger N, Dellacasa I, Svensson M, Barragan A. Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemination. Cell Microbiol 2006 8 : 1611 1623.
15. Denkers E, Gazzinelli RT. Regulation and function of T cell mediated immunity during Toxoplasma gondii infection. Clin Microbiol 1998 11 : 569 588.
16. Dowling D, Hamilton CM, O'Neill SM. A comparative analysis of cytokine responses, cell surface marker expression and MAPKs in DCs matured with LPS compared with a panel of TLR ligands. Cytokine 2008 41 : 254 262.
17. Zozulya AL, Reinke E, Baiu DC, Karman J, Sandor M, Fabry Z. Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases. J Immunol 2007 178 : 520 529.
18. Debierre-Grockiego F, Molitor N, Schwarz RT, Lüder CG. Toxoplasma gondii glycosylphosphatidylinositols up-regulate major histocompatibility complex (MHC) molecule expression on primary murine macrophages. Innate Immun 2009 15 : 25 32.
19. Subauste CS, Waal Malefyt R, Fuh F. Role of CD80 (B7.1) and CD86 (B7.2) in the immune response to an intracellular pathogen. J Immunol 1998 160 : 1831 1840.
20. Hiramoto RM, Galisteo AJ Jr., Nascimento N, Andrade HF Jr. 200 Gy sterilised Toxoplasma gondii tachyzoites maintain metabolic functions and mammalian cell invasion, eliciting cellular immunity and cytokine response similar to natural infection in mice. Vaccine 2002 20 : 2072 2078.
21. + nondendritic antigen-presenting-cells by exposure of monocytes to IFNα. J Immunol 2008 181 : 2999 3008.
22. Favali C, Tavares N, Clarêncio J, Barral A, Barral-Netto, Brodskyn C. Leishmania amazonensis infection impairs differentiation and function of human dendritic cells. J Leuk Biol 2007 82 : 1401 1406.
23. De Almeida MC, Cardoso AS, Barral-Netto M. Leishmania (Leishmania) chagasi infection alters the expression of cell adhesion and costimulatory molecules on human monocyte and macrophage. Int J Parasitol 2003 33 : 153 162.
24. Hume DA. Macrophages as APC and the dendritic cell myth. J Immunol 2008 181 : 5829 5835.
25. Fischer HG, Dörfler R, Bartholomäus S, Hadding U. Differential CD86/B7-2 expression and cytokine secretion induced by Toxoplasma gondii in macrophages from resistant or susceptible BALB H-2 congenic mice. Int Immunol 1999 11 : 341 349.
26. Sumyuen MH, Garin YJ, Derouin F. Early kinetics of Toxoplasma gondii infection in mice infected orally with cysts of a virulent strain. J Parasitol 1995 81 : 327 399.
27. Lambert H, Hitziger N, Dellacasa I, Svensson M, Barragan A. Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemination. Cell Microbiol 2006 8 : 1611 1623.
28. Damsky CH, Ilic D. Integrin signaling: it's where the action is. Curr Opin Cell Biol 2002 14 : 594 602.
29. Nourshagh S, Marelli-Berg FM. Transmigration through venular walls: a key regulator of leukocyte phenotype and function. Trends Immunol 2005 26 : 157 165.
30. Xu H, Manivannan A, Crane I, Dawson R, Liversidge J. Critical but divergent roles for CD62L and CD44 in directing blood monocytes trafficking in vivo during inflammation. Blood 2008 112 : 1166 1174.
31. Bradfield PF, Johnson-Léger CA, Zimmerli C, Imhof BA. LPS differentially regulates adhesion and transendothelial migration of human monocytes under static and flow conditions. Int Immunol 2007 20 : 247 257.