Proteomic approach to ETV5 during endometrial carcinoma invasion reveals a link to oxidative stress

Carcinogenesis

Volumn 30, Issue 8, 2009, Pages 1288-1297

  Monge, Marta ^a   Colas, Eva ^a   Doll, Andreas ^a   Gil Moreno, Antonio ^a   Castellvi, Josep ^a   Diaz, Berta ^a   Gonzalez, Marta ^a   Lopez Lopez, Rafael ^b   Xercavins, Jordi ^a   Carreras, Ramon ^c   Alameda, Francesc ^c   Canals, Francesc ^a   Gabrielli, Franco ^d   Reventos, Jaume ^a   Abal, Miguel ^a,e  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^c HOSPITAL DEL MAR   (Spain)

^d UNIVERSITY OF PISA   (Italy)

^e UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE PHOSPHORIBOSYLTRANSFERASE; ADENYLATE CYCLASE; ADENYLATE CYCLASE ASSOCIATED PROTEIN 1; CYSTATIN B; EZRIN; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 4; GESTAGEN; GLYCINE TRANSFER RNA LIGASE; HETEROGENOUS RIBONUCLEAR PARTICLE PROTEIN L; HETEROGENOUS RIBONUCLEOPROTEIN 2H9; HETEROGENOUS RIBONUCLEOPROTEIN A; HETEROGENOUS RIBONUCLEOPROTEIN A1; HETEROGENOUS RIBONUCLEOPROTEIN A3; HETEROGENOUS RIBONUCLEOPROTEIN B; HETEROGENOUS RIBONUCLEOPROTEIN B1; HETEROGENOUS RIBONUCLEOPROTEIN C; HETEROGENOUS RIBONUCLEOPROTEIN H; METHYLCROTONOYL COENZYME A CARBOXYLASE; METHYLTESTOSTERONE; ONCOPROTEIN; PROTEIN HEP27; PYRUVATE KINASE; PYRUVATE KINASE M1 ISOENZYME; TRANSALDOLASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETV5; TRANSFORMING GROWTH FACTOR BETA; TRYPTOPHAN TRANSFER RNA LIGASE; UNCLASSIFIED DRUG; ALCOHOL DEHYDROGENASE; DHRS2 PROTEIN, HUMAN; DNA BINDING PROTEIN; ETV5 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROGESTERONE; SMALL INTERFERING RNA; TUMOR MARKER;

APOPTOSIS; ARTICLE; CANCER INFILTRATION; CANCER INVASION; CANCER RECURRENCE; CELL MIGRATION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENDOMETRIUM CARCINOMA; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; CELL FRACTIONATION; CHROMATIN IMMUNOPRECIPITATION; DRUG ANTAGONISM; ENDOMETRIUM TUMOR; ENZYME IMMUNOASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; MASS SPECTROMETRY; METABOLISM; PATHOLOGY; PROTEOMICS; TUMOR CELL CULTURE; WESTERN BLOTTING;

ALCOHOL DEHYDROGENASE; APOPTOSIS; BLOTTING, WESTERN; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOMETRIAL NEOPLASMS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; OXIDATIVE STRESS; PROGESTERONE; PROTEOMICS; RNA, SMALL INTERFERING; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUBCELLULAR FRACTIONS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 69449102821     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp119     Document Type: Article

References (32)

1. Lax, S. F. et al. (1997) A dualistic model for endometrial carcinogenesis based on immunohistochemical and molecular genetic analyses. Verh. Dtsch. Ges. Pathol., 81, 228-232.
2. Potischman, N. et al. (1996) Case-control study of endogenous steroid hormones and endometrial cancer. J. Natl Cancer Inst., 88, 1127-1135.
3. Lax, S. F. et al. (1998) Comparison of estrogen and progesterone receptor, Ki-67, and p53 immunoreactivity in uterine endometrioid carcinoma and endometrioid carcinoma with squamous, mucinous, secretory, and ciliated cell differentiation. Hum. Pathol., 29, 924-931.
4. Sherman, M. E. et al. (1997) Risk factors and hormone levels in patients with serous and endometrioid uterine carcinomas. Mod. Pathol., 10, 963-968.
5. Abal, M. et al. (2007) Molecular determinants of invasion in endometrial cancer. Clin. Transl. Oncol., 9, 272-277.
6. Planaguma, J. et al. (2005) Up-regulation of ERM/ETV5 correlates with the degree of myometrial infiltration in endometrioid endometrial carcinoma. J. Pathol., 207, 422-429.
7. Monge, M. et al. (2007) ERM/ETV5 up-regulation plays a role during myometrial infiltration through matrix metalloproteinase-2 activation in endometrial cancer. Cancer Res., 67, 6753-6759.
8. Alban, A. et al. (2003) A novel experimental design for comparative twodimensional gel analysis: Two-dimensional difference gel electrophoresis incorporating a pooled internal standard. Proteomics 3, 36-44.
9. Shevchenko, A. et al. (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem., 68 850-858.
10. Esselens, C. W. et al. (2008) Metastasis-associated C4. 4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17. Biol. Chem., 389, 1075-1084.
11. Gabrielli, F. et al. (1995) A nuclear protein, synthesized in growth-arrested human hepatoblastoma cells, is a novel member of the short-chain alcohol dehydrogenase family. Eur. J. Biochem., 232 473-477.
12. Shafqat, N. et al. (2006) Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue. Cell. Mol. Life Sci., 63, 1205-1213.
13. Pellegrini, S. et al. (2002) A human short-chain dehydrogenase/ reductase gene: Structure, chromosomal localization, tissue expression and subcellular localization of its product. Biochim. Biophys. Acta 1574, 215-222.
14. Oppermann, U. (2007) Carbonyl reductases: The complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology. Annu. Rev. Pharmacol. Toxicol., 47, 293-322.
15. Wu, W. S. (2006) The signaling mechanism of ROS in tumor progression. Cancer Metastasis Rev., 25, 695-705.
16. Hanekamp, E. E. et al. (2003) Consequences of loss of progesterone receptor expression in development of invasive endometrial cancer. Clin. Cancer Res., 9, 4190-4199.
17. Vignjevic, D. et al. (2008) Reorganisation of the dendritic actin network during cancer cell migration and invasion. Semin. Cancer Biol., 18, 12-22.
18. Yamaguchi, H. et al. (2007) Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim. Biophys. Acta, 1773, 642-652.
19. Gimona, M. et al. (2008) Assembly and biological role of podosomes and invadopodia. Curr. Opin. Cell Biol., 20, 235-241.
20. Acconcia, F. et al. (2006) Estrogen and tamoxifen induce cytoskeletal remodeling and migration in endometrial cancer cells. Endocrinology, 147, 1203-1212.
21. Jakowlew, S. B. (2006) Transforming growth factor-beta in cancer and metastasis. Cancer Metastasis Rev., 25, 435-457.
22. Leivonen, S. K. et al. (2007) Transforming growth factor-beta signaling in cancer invasion and metastasis. Int. J. Cancer, 121, 2119-2124.
23. Piestrzeniewicz-Ulanska, D. et al. (2004) TGF-beta signaling is disrupted in endometrioid-type endometrial carcinomas. Gynecol. Oncol., 95, 173-180.
24. Yabushita, H. et al. (2000) The association of transforming growth factorbeta 1 with myometrial invasion of endometrial carcinomas through effects on matrix metalloproteinase. J. Obstet. Gynaecol. Res., 26, 163-170.
25. Storz, P. (2005) Reactive oxygen species in tumor progression. Front. Biosci., 10, 1881-1896.
26. Wilson, L. A. et al. (2005) ets-1 is transcriptionally up-regulated by H2O2 via an antioxidant response element. FASEB J. 19, 2085-2087.
27. Nelson, K. K. et al. (2006) Redox-dependent matrix metalloproteinase-1 expression is regulated by JNK through Ets and AP-1 promoter motifs. J. Biol. Chem., 281, 14100-14110.
28. Yasuda, M. et al. (1999) Stimulation of in vitro angiogenesis by hydrogen peroxide and the relation with ETS-1 in endothelial cells. Life Sci., 64, 249-258.
29. Ni, W. et al. (2007) Ets-1 is a critical transcriptional regulator of reactive oxygen species and p47(phox) gene expression in response to angiotensin II. Circ. Res., 101, 985-994.
30. Helguera, P. et al. (2005) ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons. J. Neurosci. 25, 2295-2303.
31. Hayashi, T. et al. (2005) l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits. Proc. Natl Acad. Sci. USA, 102, 13681-13686.
32. Wilson, L. A. et al. (2004) Role of the transcription factor Ets-1 in cisplatin resistance. Mol. Cancer Ther., 3, 823-832.