Pancreas: C-peptide reveals possible Β-cell reactivation in pregnancy

Nature Reviews Endocrinology

Volumn 5, Issue 7, 2009, Pages 364-365

  Brunskill, Nigel J ^a  

^a LEICESTER GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; SOMATOMEDIN C;

CELL FUNCTION; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MATERNAL DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PREGNANCY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SHORT SURVEY; BLOOD; DIABETES MELLITUS; METABOLISM; NOTE; PANCREAS; PATHOLOGY;

C-PEPTIDE; DIABETES MELLITUS; FEMALE; HUMANS; INSULIN-SECRETING CELLS; PANCREAS; PREGNANCY;

EID: 69449097949     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2009.108     Document Type: Short Survey

References (9)

1. sherry, n. A., Tsai, e. B. Herold, K. C. natural history of a-cell function in type 1 diabetes. Diabetes 54 (Suppl. 2), s32-s39 (2005).
2. nielsen, L. R., Rehfeld, J. F., Pedersen-Bjergaard. U., Damm, P. Mathiesen, e. R. Pregnancy-induced rise in serum C-peptide concentrations in women with type 1 diabetes. Diabetes Care doi: dc08-1832v1-0.
3. Löhr, M. Klöppel, G. Residual insulin positivity and pancreatic atrophy in relation to duration of chronic type 1 (insulin-dependent) diabetes mellitus and microangiopathy. Diabetologia 30, 757-762 (1987).
4. Butler, P. C., Meier, J. J. Butler, A. e. Bhushan, A. The replication of a cells in normal physiology, in disease and for therapy. Nat. Clin. Pract. Endocrinol. Metab. 3, 758-768 (2007).
5. Pihoker, P., Gilliam, L. K., Hampe, C. s. Lernmark, A. Autoantibodies in diabetes. Diabetes 54 (Suppl. 2), s52-s61 (2005).
6. Bianchi, D. w., Zickwolf, G. K., weil, G. J., sylvester, s. DeMaria, M. A. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum. Proc. Natl Acad. Sci. USA 93, 705-708 (1996).
7. Khosrotehrani, K. Bianchi, D. w. Multi-lineage potential of fetal cells in maternal tissue: a legacy in reverse. J. Cell. Sci. 118, 1559-1563 (2005).
8. Panero, F. et al. Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic patients. Diabetes Care 32, 301-305 (2009).
9. Hills, C. e. Brunskill, n. J. Cellular and physiological effects of C-peptide. Clin. Sci. (Lond.) 116, 565-574 (2009).