Chloroacetonitrile induces oxidative stress and apoptosis in mouse fetal liver

Toxicology Letters

Volumn 190, Issue 2, 2009, Pages 123-127

  Abdel Naim, Ashraf B ^a   Nagy, Ayman A ^b   Mohamadin, Ahmed M ^c   El Mazar, Hala M ^d   Ahmed, Ahmed E ^d  

^a Ain Shams University   (Egypt)

^b TANTA UNIVERSITY   (Egypt)

^c TAIBAH UNIVERSITY   (Saudi Arabia)

^d University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Chloroacetonitrile; Fetal liver; Water disinfection by products

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CASPASE 3; CHLOROACETONITRILE; GENOMIC DNA; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLYCOGEN; MALONALDEHYDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL FRACTIONATION; CELL STRESS; CELL VACUOLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOPLASM; CYTOSOL; DNA DAMAGE; DNA FRAGMENTATION; ENZYME ACTIVITY; FEMALE; FETUS; FETUS LIVER; GESTATIONAL AGE; HISTOPATHOLOGY; KARYOTYPE; LIVER CELL; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; TOXICOKINETICS;

ACETONITRILES; ANIMALS; APOPTOSIS; BODY WEIGHT; CASPASE 3; DEOXYGUANOSINE; DNA FRAGMENTATION; FEMALE; FETUS; GLUTATHIONE; LIVER; MALONDIALDEHYDE; MICE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PREGNANCY; SURVIVAL; WATER POLLUTANTS, CHEMICAL;

MUS;

EID: 69449085986     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.06.867     Document Type: Article

References (50)

1. Abdel-Aziz A.A., Abdel-Rahman S.Z., Nouraldin A.M., Shouman S.A., Loh J.P., and Ahmed A.E. Effect of glutathione modulation on molecular interaction of [14C]-chloroacetonitrile with maternal and fetal DNA in mice. Reprod. Toxicol. 7 (1993) 263-272
2. Ahmed A.E., Hussein G.I., Loh J.P., and Abdel-Rahman S.Z. Studies on the mechanism of haloacetonitrileinduced gastrointestinal toxicity: interaction of dibromoacetonitrile with glutathione and glutathione-S transferase in rats. J. Biochem. Toxicol. 6 (1991) 115-121
3. Ahmed A.E., Jacob S., and Nouraldeen A.M. Chloroacetonitrile (CAN) induces glutathione depletion and 8-hydroxylation of guanine bases in rat gastric mucosa. J. Biochem. Mol. Toxicol. 13 (1999) 119-126
4. Ahmed A.E., Campbell G.A., and Jacob S. Neurological impairment in fetal mouse brain by drinking water disinfectant byproducts. Neurotoxicology 26 (2005) 633-640
5. Ahmed A.E., Jacob S., Campbell G.A., Harirah H.M., Perez-Polo J.R., and Johnson M.K. Fetal origin of adverse pregnancy outcome: the water disinfectant by-product chloroacetonitrile induces oxidative stress and apoptosis in mouse fetal brain. Brain Res. Dev. Brain Res. 159 (2005) 1-11
6. Ahmed A.E., El-Mazar H., Nagy A., and Abdel-Naim A. Chloroacetonitrile induces intrauterine growth restriction and musculoskeletal toxicity in fetal mouse. Toxicol. Ind. Health 24 (2008) 511-518
7. Barcelo D., Maris F.A., Geerdink R.B., Frei R., Wde Jong G.J., and Brinkman U.A. Comparison between positive, negative and chloride-enhanced negative chemical ionization of organophosphorus pesticides in on-line liquid chromatography-mass spectrometry. J. Chromatogr. 8 (1987) 65-76
8. Bove F., Shim Y., and Zeitz P. Drinkingwater contaminants and adverse pregnancy outcomes: a review. Environ. Health Prespect. 110 (2002) 61-74
9. Bradford M. Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Ann. Biochem. 72 (1976) 360-365
10. Bull R.J., Meier J.R., Robinson M., Ringhand H.P., Laurie R.D., and Stober J.A. Evaluation of mutagenic and carcinogenic properties of brominated and chlorinated acetonitriles: by-products of chlorination. Fundam. Appl. Toxicol. 5 (1985) 1065-1074
11. Cotton R.T., and Walkden H.H. The role of sorption in the fumigation of stored grain and cereal products. J. Kans. Entomol. Soc. 17 (1968) 98
12. Daxhelet G.A., Coene M.M., Hoet P.P., and Cocito C.G. Spectrofluorometry of dyes with DNAs of different base composition and conformation. Anal. Biochem. 179 (1989) 401-403
13. Floyd R.A. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis 11 (1990) 1447-1450
14. Freemark M., Comer M., Mularoni T., D'Ercole A.J., Grandis A., and Kodack L. Nutritional regulation of the placental lactogen receptor in fetal liver: implications for fetal metabolism and growth. Endocrinology 125 (1989) 1504-1512
15. Gallagher M.D., Nuckols J.R., Stallones L., and Savitz D.A. Exposure to trihalomethanes and adverse pregnancy outcomes. Epidemiology 9 (1998) 484-489
16. Graves C.G., Matanoski G.M., and Tardiff R.G. Weight of evidence for an association between adverse reproductive and developmental effects and exposure to disinfection by-products: a critical review. Regul. Toxicol. Pharmacol. 34 (2001) 103-124
17. Gu C., Casaccia-Bonnefil P., Srinivasan A., and Chao M.V. Oligodendrocyte apoptosis mediated by caspase activation. J. Neurosci. 19 (1999) 3043-3049
18. Hattori-Nakakuki Y., Nishigori C., Okamoto K., Imamura S., Hiai H., and Toyokuni S. Formation of 8-hydroxy-2′-deoxyguanosine in epidermis of hairless mice exposed to near-UV. Biochem. Biophys. Res. Commun. 201 (1994) 1132-1139
19. Huppertz B., and Kingdom J.C. Apoptosis in the trophoblast-role of apoptosis in placental morphogenesis. J. Soc. Gynecol. Investig. 11 (2004) 353-362
20. Hwang B.F., Magnus P., and Jaakkola J.J. Risk of specific birth defects in relation to chlorination and the amount of natural organic matter in the water supply. Am. J. Epidemiol. 156 (2002) 374-382
21. IARC, International Agency for Research on Cancer, 1991. Monographs on the Evaluation of the Carcinogenic Risk to Humans. Halogenated Acetonitriles, vol. 52, Lyon, France.
22. Jacob S., Abdel-Aziz A.A., Shouman S.A., and Ahmed A.E. Effect of glutathione modulation of the distribution and transplacental uptake of 2-[14C]-chloroacetonitrile (CAN) quantitative whole-body autoradiographic study in pregnant mice. Toxicol. Ind. Health 14 (1998) 533-546
23. Jiao Z.Q., Guo Y.C., and Xu Y. The effects of acrylonitrile on cell apoptosis, proliferation and related genes expression of rat normal and tumor glial cells. Zhonghua Yu Fang Yi Xue Za Zhi 42 (2008) 405-409
24. Keirnan J.A. Histological and Histochemical Methods Theory and Practice. Third edition (1999), Butterworth-Heinemann, Replika Press Pvt Ltd, Delhi, India
25. King W.D., Dodds L., and Allen A.C. Relation between stillbirth and specific chlorination by-products in public water supplies. Environ. Health Perspect. 108 (2000) 883-886
26. Klotz J.B., and Pyrch L.A. Neural tube defects and drinking water disinfection by-products. Epidemiology 10 (1999) 383-390
27. Kohen R., and Nyska A. Oxidation of biological systems: previous termoxidative stressnext term phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol. Pathol. 30 (2002) 620-650
28. Krien P.M., Margou V., and Kermici M. Electrochemical determination of femtomole amounts of free reduced and oxidized glutathione. Application to human hair follicles. J. Chromatogr. 576 (1992) 255-261
29. Laws G.M., and Adams S.P. Measurement of 8-OHdG in DNA by HPLC/ECD: the importance of DNA purity. Biotechniques 20 (1996) 36-38
30. Le Curieux F., Giller S., Gauthier L., Erb F., and Marzin D. Study of the genotoxic activity of six halogenated acetonitriles, using the SOS chromotest, the Ames-fluctuation test and the newt micronucleus test. Mutat. Res. 341 (1995) 289-302
31. Lin E.L.C., Daniel F.B., Herren-Freund S.L., and Pereira M.A. Haloacetonitriles: metabolism, genotoxicity, and tumor-initiating activity. Environ. Health Perspect. 69 (1986) 67-71
32. Lin E.L., and Guion C.W. Interaction of haloacetonitriles with glutathione and glutathione-S-transferase. Biochem. Pharmacol. 38 (1989) 685-688
33. Lipscomb J.C., El-Demerdash E., and Ahmed A.E. Haloacetonitriles: metabolism and toxicity. Rev. Environ. Contam. Toxicol. 198 (2009) 169-200
34. Magnus K.G., Milla A.J., Sinclair-Smith C.C., and Rode H. Intrahepatic fetus-in-fetu: a case report and review of the literature. J. Pediatr. Surg. 34 (1999) 1861-1864
35. Matt, J., 1968. US Patent No. 3,608,084.
36. McGuire M.J., McLain J.L., and Obolensky A. Information Collection Rule Data Analysis (2002), AWWA Foundation and AWWA, Denver, CO
37. Medlock E.S., and Haar J.L. The liver hemopoietic environment. I. Developing hepatocytes and their role in fetal hemopoiesis. Anat. Rec. 207 (1983) 31-41
38. Mink F.L., Coleman W.E., Munch J.W., Kaylor W.H., and Ringhand H.P. In vivo formation of halogenated reaction products following peroral sodium hypochlorite. Bull. Environ. Contam. Toxicol. 30 (1983) 394-399
39. Moudgal C.J., Lipscomb J.C., and Bruce R.M. Potential health effects of drinking water disinfectant byproducts using quantitative structure activity relationship. Toxicology 147 (2000) 109-131
40. Muellner M.G., Wagner E.D., McCalla K., Richardson S.D., Woo Y.T., and Plewa M.J. Haloacetonitriles vs. regulated haloacetic acids: are nitrogen containing DBPs more toxic?. Environ. Sci. Technol. 41 (2007) 645-651
41. Nieuwenhuijsen M.J., Toledano M.B., Eaton N.E., Fawell J., and Elliott P. Chlorination disinfection byproducts in water and their association with adverse reproductive outcomes: a review. Occup. Environ. Med. 57 (2000) 73-85
42. Ramachandran V., Perez A., Juanjuan C.C., Duraisamy S., Schenker S., and Henderson G. In utero ethanol exposure causes mitochondrial dysfunction, which can result in apoptotic cell death in fetal brain: a potential role for 4-hydroxynonenal. Alcohol Clin. Exp. Res. 25 (2001) 862-871
43. Richard M.J., Portal B., Meo J., Coudry C., Hadjian A., and Favier A. Malonaldehyde kit evaluated for determining plasma and lipoprotein fractions that react with thiobarbituric acid. Clin. Chem. 38 (1992) 704-709
44. Richardson S.D., Plewa M.J., Wagner E.D., Schoeny R., and Demarini D.M. Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research. Mutat. Res. 636 (2007) 178-242
45. Shouman S.A., Abdel-Aziz A.H., and Ahmed A.E. The effect on replicative and unscheduled DNA synthesis in cultured embryonic tissue after maternal administration of chloroacetonitrile. J. Egypt Natl. Cancer Inst. 6 (1993) 351-364
46. Smith M.K., George E.L., Zenick H., Manson J.M., and Stober J.A. Developmental toxicity of halogenated acetonitriles: drinking water by-products of chlorine disinfection. Toxicology 46 (1987) 83-93
47. Theiler K. The house mouse. Atlas of Embryonic Development. Second edition (1989), Springer-Verag, New york, Berlin Heidelberg, London, Paris, Tokyo pp. 21-129
48. Weiss B., and Landrigan P.J. The developing brain and the environment: an introduction. Environ. Health Perspect. 108 (2000) 373-374
49. Wright J.M., Schwartz J., and Dockery D.W. Effect of trihalomethane exposure on fetal development. Occup. Environ. Med. 60 (2003) 173-180
50. Wright J.M., Schwartz J., and Dockery D.W. The effect of disinfection by-products and mutagenic activity on birth weight and gestational duration. Environ. Health Perspect. 112 (2004) 920-925