메뉴 건너뛰기




Volumn 5, Issue 6, 2008, Pages 793-796

The search for new anticoagulants: Dabigatran etexilate

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBIN; ANTIVITAMIN K; BLOOD CLOTTING FACTOR 10A INHIBITOR; DABIGATRAN ETEXILATE; ENOXAPARIN; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; THROMBIN INHIBITOR; WARFARIN; XIMELAGATRAN;

EID: 69449083888     PISSN: 14750708     EISSN: 1744831X     Source Type: Journal    
DOI: 10.2217/14750708.5.6.793     Document Type: Editorial
Times cited : (2)

References (16)
  • 2
    • 34548456509 scopus 로고    scopus 로고
    • Beyond unfractionated heparin and warfarin:current and future advances
    • Hirsh J, O'Donnell M, Eikelboom JW: Beyond unfractionated heparin and warfarin:current and future advances. Circulation 116, 552-560 (2007).
    • (2007) Circulation , vol.116 , pp. 552-560
    • Hirsh, J.1    O'Donnell, M.2    Eikelboom, J.W.3
  • 3
    • 0031936090 scopus 로고    scopus 로고
    • Thrombin binds to soluble fibrin degradation products where it is protected from inhibition by heparin-antithrombin but susceptible to inactivation by antithrombin-independent inhibitors
    • Weitz JI, Leslie B, Hudoba M: Thrombin binds to soluble fibrin degradation products where it is protected from inhibition by heparin-antithrombin but susceptible to inactivation by antithrombin-independent inhibitors. Circulation 97, 544-552 (1998).
    • (1998) Circulation , vol.97 , pp. 544-552
    • Weitz, J.I.1    Leslie, B.2    Hudoba, M.3
  • 4
    • 23244432463 scopus 로고    scopus 로고
    • Ximelagatran for stroke prevention in atrial fibrillation
    • Boos CJ, Lip GYH: Ximelagatran for stroke prevention in atrial fibrillation. Expert Rev. Cardiovasc. Ther. 3, 551-563 (2005).
    • (2005) Expert Rev. Cardiovasc. Ther , vol.3 , pp. 551-563
    • Boos, C.J.1    Lip, G.Y.H.2
  • 5
    • 35248897610 scopus 로고    scopus 로고
    • Ximelagatran/melagatran against conventional anticoagulation: A meta-analysis based on 22,639 patients
    • Testa L, Andreotti F, Biondi Zoccai GG, Burzotta F, Bellocci F, Crea F: Ximelagatran/melagatran against conventional anticoagulation: a meta-analysis based on 22,639 patients. Int. J. Cardiol. 122, 117-124 (2007).
    • (2007) Int. J. Cardiol , vol.122 , pp. 117-124
    • Testa, L.1    Andreotti, F.2    Biondi Zoccai, G.G.3    Burzotta, F.4    Bellocci, F.5    Crea, F.6
  • 6
    • 69949161498 scopus 로고    scopus 로고
    • Agnelli G, Eriksson BI, Cohen AT et al.: on behalf of the EXTEND Study Group: Safety assessment of new antithrombotic agents: lessons from the EXTEND study on ximelagatran. Thromb Res. (2008) (Epub ahead of print).
    • Agnelli G, Eriksson BI, Cohen AT et al.: on behalf of the EXTEND Study Group: Safety assessment of new antithrombotic agents: lessons from the EXTEND study on ximelagatran. Thromb Res. (2008) (Epub ahead of print).
  • 7
    • 33746899054 scopus 로고    scopus 로고
    • The challenges of new drugs benefits and risks analysis: Lessons from the ximelagatran FDA Cardiovascular Advisory Committee
    • Boudes PF: The challenges of new drugs benefits and risks analysis: lessons from the ximelagatran FDA Cardiovascular Advisory Committee. Contemp. Clin. Trials 27, 432-440 (2006).
    • (2006) Contemp. Clin. Trials , vol.27 , pp. 432-440
    • Boudes, P.F.1
  • 9
    • 34548031359 scopus 로고    scopus 로고
    • The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy mate subjects
    • Stangier J, Rathgen K, Staehle H, Gansser D, Roth W: The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy mate subjects. Br. J. Clin. Pharmacol. 64, 292-303 (2007).
    • (2007) Br. J. Clin. Pharmacol , vol.64 , pp. 292-303
    • Stangier, J.1    Rathgen, K.2    Staehle, H.3    Gansser, D.4    Roth, W.5
  • 10
    • 13244266944 scopus 로고    scopus 로고
    • Dose escalating safety study of a new oral direct thrombin inhibitor, dabigatran etexilate, in patients undergoing total hip replacement: BISTRO I
    • Eriksson BI, Dahl OE, Ahnfelt L et al.: Dose escalating safety study of a new oral direct thrombin inhibitor, dabigatran etexilate, in patients undergoing total hip replacement: BISTRO I.J. Thromb. Haemost. 2, 1573-1580 (2004).
    • (2004) J. Thromb. Haemost , vol.2 , pp. 1573-1580
    • Eriksson, B.I.1    Dahl, O.E.2    Ahnfelt, L.3
  • 11
    • 17644409026 scopus 로고    scopus 로고
    • A new oral direct thrombin inhibitor, dabigatran etexilate, compared with enoxaparin for prevention of thromboembolic events following total hip or knee replacement: The BISTRO II randomized trial
    • Eriksson BI, Dahl OE, Bueller HR et al.: A new oral direct thrombin inhibitor, dabigatran etexilate, compared with enoxaparin for prevention of thromboembolic events following total hip or knee replacement: the BISTRO II randomized trial. J. Thromb. Haemost. 3, 103-111 (2005).
    • (2005) J. Thromb. Haemost , vol.3 , pp. 103-111
    • Eriksson, B.I.1    Dahl, O.E.2    Bueller, H.R.3
  • 12
    • 34250749339 scopus 로고    scopus 로고
    • A new oral anticoagulant, dabigatran etexilate, is effective and safe in preventing venous thromboembolism after total knee replacement surgery
    • Eriksson BI, Dahl OE, van Dijk CN et al.: A new oral anticoagulant, dabigatran etexilate, is effective and safe in preventing venous thromboembolism after total knee replacement surgery. Blood 108, 11 (2006).
    • (2006) Blood , vol.108 , pp. 11
    • Eriksson, B.I.1    Dahl, O.E.2    van Dijk, C.N.3
  • 13
    • 34548575058 scopus 로고    scopus 로고
    • RE-NOVATE Study Group. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomised, double-blind, non-inferiority trial
    • Eriksson BI, Dahl OE, Rosencher N et al.; RE-NOVATE Study Group. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 370, 949-956 (2007).
    • (2007) Lancet , vol.370 , pp. 949-956
    • Eriksson, B.I.1    Dahl, O.E.2    Rosencher, N.3
  • 14
    • 57649123692 scopus 로고    scopus 로고
    • The oral thrombin inhibitor dabigatran etexilate vs the North American enoxaparin regimen for the prevention of venous thromboembolism after knee arthroplasty surgery
    • The RE-MOBILIZE Writing Committee:, DOI: 10.1016/j.arth.2008.01-132 , Epub ahead of print
    • The RE-MOBILIZE Writing Committee: The oral thrombin inhibitor dabigatran etexilate vs the North American enoxaparin regimen for the prevention of venous thromboembolism after knee arthroplasty surgery. J. Arthroplasty DOI: 10.1016/j.arth.2008.01-132 (2008) (Epub ahead of print).
    • (2008) J. Arthroplasty
  • 15
    • 35348879239 scopus 로고    scopus 로고
    • Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study)
    • Ezekowitz MD, Reilly PA, Nehmiz G et al.: Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study). Am. J. Cardiol. 100 (9), 1419-1426 (2007).
    • (2007) Am. J. Cardiol , vol.100 , Issue.9 , pp. 1419-1426
    • Ezekowitz, M.D.1    Reilly, P.A.2    Nehmiz, G.3
  • 16
    • 5144229318 scopus 로고    scopus 로고
    • Synthetic selective inhibitors of coagulation factor Xa strongly inhibit thrombin generation without affecting initial thrombin forming time necessary for platelet activation in hemostasis
    • Ieko M, Tarumi T, Takeda M, Naito S, Nikabayashi T, Koike T: Synthetic selective inhibitors of coagulation factor Xa strongly inhibit thrombin generation without affecting initial thrombin forming time necessary for platelet activation in hemostasis. J. Thromb. Haemost. 2, 612-618 (2004).
    • (2004) J. Thromb. Haemost , vol.2 , pp. 612-618
    • Ieko, M.1    Tarumi, T.2    Takeda, M.3    Naito, S.4    Nikabayashi, T.5    Koike, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.