Erectile dysfunction after radiotherapy for prostate cancer

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 32, Issue 4, 2009, Pages 443-447

  Mendenhall, William M ^a,b,c   Henderson, Randal H ^a,b   Indelicato, Daniel J ^a,b   Keole, Sameer R ^a,b   Mendenhall, Nancy P ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

Erectile dysfunction; Prostate cancer; Radiotherapy

Indexed keywords

PHOSPHODIESTERASE INHIBITOR; PROSTAGLANDIN E1; SILDENAFIL; TADALAFIL; YOHIMBINE;

ANDROGEN DEPRIVATION THERAPY; BRACHYTHERAPY; CANCER RADIOTHERAPY; ERECTILE DYSFUNCTION; EXTERNAL BEAM RADIOTHERAPY; HUMAN; PENIS; PENIS ERECTION; PROSTATE CANCER; PROSTATECTOMY; QUALITY OF LIFE; RADIATION DOSE; REVIEW; SEXUAL INTERCOURSE; SINGLE NUCLEOTIDE POLYMORPHISM;

AGE DISTRIBUTION; AGED; DOSE-RESPONSE RELATIONSHIP, RADIATION; ERECTILE DYSFUNCTION; HUMANS; INCIDENCE; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROSTATECTOMY; PROSTATIC NEOPLASMS; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SEVERITY OF ILLNESS INDEX;

EID: 69349089108     PISSN: 02773732     EISSN: 1537453X     Source Type: Journal    
DOI: 10.1097/COC.0b013e318173a563     Document Type: Review

References (35)

1. Walsh PC, Donker PJ. Impotence following radical prostatectomy: insight into etiology and prevention. 1982. J Urol. 2002;167:1005-1010.
2. Zelefsky MJ, Eid JF. Elucidating the etiology of erectile dysfunction after definitive therapy for prostatic cancer. Int J Radiat Oncol Biol Phys. 1998;40:129-133.
3. Burnett AL, Aus G, Canby-Hagino ED, et al. Erectile function outcome reporting after clinically localized prostate cancer treatment. J Urol. 2007;178:597-601. (Pubitemid 47030514)
4. Kiteley RA, Lee WR, deGuzman AF, et al. Radiation dose to the neurovascular bundles or penile bulb does not predict erectile dysfunction after prostate brachytherapy. Brachytherapy. 2002;1:90-94.
5. Macdonald AG, Keyes M, Kruk A, et al. Predictive factors for erectile dysfunction in men with prostate cancer after brachytherapy: is dose to the penile bulb important? Int J Radiat Oncol Biol Phys. 2005;63:155-163. (Pubitemid 41583554)
6. Stanford JL, Feng Z, Hamilton AS, et al. Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer: the Prostate Cancer Outcomes Study. JAMA. 2000;283:354-360. (Pubitemid 30051753)
7. Litwin MS, Flanders SC, Pasta DJ, et al. Sexual function and bother after radical prostatectomy or radiation for prostate cancer: multivariate qualityof- life analysis from CaPSURE. Cancer of the Prostate Strategic Urologic Research Endeavor. Urology. 1999;54:503-508.
8. Zagar TM, Stock RG, Cesaretti JA, et al. Assessment of postbrachytherapy sexual function: a comparison of the IIEF-5 and the MSEFS. Brachytherapy. 2007;6:26-33.
9. Robinson JW, Moritz S, Fung T. Meta-analysis of rates of erectile function after treatment of localized prostate carcinoma. Int J Radiat Oncol Biol Phys. 2002;54:1063-1068. (Pubitemid 35292617)
10. Akbal C, Tinay I, Simsek F, et al. Erectile dysfunction following radiotherapy and brachytherapy for prostate cancer: pathophysiology, prevention and treatment. Int Urol Nephrol. 2008;40:355-363.
11. Brown MW, Brooks JP, Albert PS, et al. An analysis of erectile function after intensity modulated radiation therapy for localized prostate carcinoma. Prostate Cancer Prostatic Dis. 2007;10:189-193. (Pubitemid 46881671)
12. Peters CA, Stock RG, Cesaretti JA, et al. TGFB1 single nucleotide polymorphisms are associated with adverse quality of life in prostate cancer patients treated with radiotherapy. Int J Radiat Oncol Biol Phys. 2008;70:752-759.
13. van der Wielen GJ, Mulhall JP, Incrocci L. Erectile dysfunction after radiotherapy for prostate cancer and radiation dose to the penile structures: a critical review. Radiother Oncol. 2007;84:107-113. (Pubitemid 47284535)
14. Cesaretti JA, Kao J, Stone NN, et al. Effect of low dose-rate prostate brachytherapy on the sexual health of men with optimal sexual function before treatment: analysis at > or = 7 years of follow-up. BJU Int. 2007;100:362-367. (Pubitemid 47036592)
15. Bottomley D, Ash D, Al Qaisieh B, et al. Side effects of permanent I125 prostate seed implants in 667 patients treated in Leeds. Radiother Oncol. 2007;82:46-49. (Pubitemid 46097133)
16. Khaksar SJ, Laing RW, Henderson A, et al. Biochemical (prostate-specific antigen) relapse-free survival and toxicity after I-125 low-dose-rate prostate brachytherapy. BJU Int. 2006;98:1210-1215. (Pubitemid 44721226)
17. Lehrer S, Cesaretti J, Stone NN, et al. Urinary symptom flare after brachytherapy for prostate cancer is associated with erectile dysfunction and more urinary symptoms before implantation. BJU Int. 2006;98:979-981. (Pubitemid 44536443)
18. Selek U, Cheung R, Lii M, et al. Erectile dysfunction and radiation dose to penile base structures: a lack of correlation. Int J Radiat Oncol Biol Phys. 2004;59:1039-1046. (Pubitemid 38834296)
19. Roach M, Winter K, Michalski JM, et al. Penile bulb dose and impotence after three-dimensional conformal radiotherapy for prostate cancer on RTOG 9406: findings from a prospective, multi-institutional, phase I/II dose-escalation study. Int J Radiat Oncol Biol Phys. 2004;60:1351-1356. (Pubitemid 39601851)
20. Mangar SA, Sydes MR, Tucker HL, et al. Evaluating the relationship between erectile dysfunction and dose received by the penile bulb: using data from a randomised controlled trial of conformal radiotherapy in prostate cancer (MRC RT01, ISRCTN47772397). Radiother Oncol. 2006;80:355-362.
21. Slater JD, Rossi CJ Jr, Yonemoto LT, et al. Proton therapy for prostate cancer: the initial Loma Linda University experience. Int J Radiat Oncol Biol Phys. 2004;59:348-352. (Pubitemid 38622585)
22. Kao J, Turian J, Meyers A, et al. Sparing of the penile bulb and proximal penile structures with intensity-modulated radiation therapy for prostate cancer. Br J Radiol. 2004;77:129-136. (Pubitemid 38313226)
23. Buyyounouski MK, Horwitz EM, Price RA, et al. Intensity-modulated radiotherapy with MRI simulation to reduce doses received by erectile tissue during prostate cancer treatment. Int J Radiat Oncol Biol Phys. 2004;58:743-749.
24. Rossi CJ Jr, Slater JD, Yonemoto LT, et al. Influence of patient age on biochemical freedom from disease in patients undergoing conformal proton radiotherapy of organ-confined prostate cancer. Urology. 2004;64:729-732.
25. Vargas C, Mahajan C, Fryer A, et al. Rectal dose-volume differences using proton radiotherapy and a rectal balloon or water alone for the treatment of prostate cancer. Int J Radiat Oncol Biol Phys. 2007;69:1110-1116. (Pubitemid 47625849)
26. Wilke DR, Parker C, Andonowski A, et al. Testosterone and erectile function recovery after radiotherapy and long-term androgen deprivation with luteinizing hormone-releasing hormone agonists. BJU Int. 2006;97:963-968.
27. Teloken PE, Ohebshalom M, Mohideen N, et al. Analysis of the impact of androgen deprivation therapy on sildenafil citrate response following radiation therapy for prostate cancer. J Urol. 2007;178:2521-2525. (Pubitemid 350052155)
28. Miller DC, Wei JT, Dunn RL, et al. Use of medications or devices for erectile dysfunction among long-term prostate cancer treatment survivors: potential influence of sexual motivation and/or indifference. Urology. 2006;68:166-171.
29. Schiff JD, Bar-Chama N, Cesaretti J, et al. Early use of a phosphodiesterase inhibitor after brachytherapy restores and preserves erectile function. BJU Int. 2006;98:1255-1258. (Pubitemid 44721237)
30. Zelefsky MJ, McKee AB, Lee H, et al. Efficacy of oral sildenafil in patients with erectile dysfunction after radiotherapy for carcinoma of the prostate. Urology. 1999;53:775-778. (Pubitemid 29163044)
31. Incrocci L, Hop WC, Slob AK. Efficacy of sildenafil in an open-label study as a continuation of a double-blind study in the treatment of erectile dysfunction after radiotherapy for prostate cancer. Urology. 2003;62:116-120. (Pubitemid 36802083)
32. Incrocci L, Koper PC, Hop WC, et al. Sildenafil citrate (Viagra) and erectile dysfunction following external beam radiotherapy for prostate cancer: a randomized, double-blind, placebo-controlled, cross-over study. Int J Radiat Oncol Biol Phys. 2001;51:1190-1195. (Pubitemid 33116310)
33. Incrocci L, Slob AK, Hop WC. Tadalafil (Cialis) and erectile dysfunction after radiotherapy for prostate cancer: an open-label extension of a blinded trial. Urology. 2007;70:1190-1193. (Pubitemid 350297381)
34. Incrocci L, Slagter C, Slob AK, et al. A randomized, double-blind, placebocontrolled, cross-over study to assess the efficacy of tadalafil (Cialis) in the treatment of erectile dysfunction following three-dimensional conformal external-beam radiotherapy for prostatic carcinoma. Int J Radiat Oncol Biol Phys. 2006;66:439-444. (Pubitemid 44332743)
35. Canada AL, Neese LE, Sui D, et al. Pilot intervention to enhance sexual rehabilitation for couples after treatment for localized prostate carcinoma. Cancer. 2005;104:2689-2700. (Pubitemid 41798279)