In vitro interactions between splenocytes and dansylamide dye-embedded nanoparticles detected by flow cytometry

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 5, Issue 3, 2009, Pages 298-304

  Nyland, Jennifer F ^a   Bai, Jennifer J K ^b   Katz, Howard E ^b   Silbergeld, Ellen K ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Cellular function; Flow cytometry; In vitro; Nanotoxicology

Indexed keywords

ACTIVATION STATE; APOPTOSIS; BIOLOGICAL ACTIVITIES; BIOLOGICAL SIGNALS; CELL FUNCTIONS; CELL RESPONSE; CELLULAR FUNCTION; COSTIMULATION; COVALENTLY BOUND; CULTURE SYSTEMS; DANSYLAMIDE; EMBEDDED NANOPARTICLES; IN VITRO; NANOTOXICOLOGY; NOVEL METHODS; QUANTITATIVE INFORMATION; SPLENOCYTES;

BIOACTIVITY; CELL CULTURE; CELL DEATH; CELL MEMBRANES; FLOW CYTOMETRY; NANOPARTICLES; SELF ASSEMBLY; SIGNAL DETECTION; VISUALIZATION;

BIOINFORMATICS;

BIOLOGICAL MARKER; DYE; NANOPARTICLE; SILOXANE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL LEVEL; CELL STIMULATION; COVALENT BOND; CYTOTOXICITY; DRUG ACTIVITY; FEMALE; FLOW CYTOMETRY; HUMAN; MOUSE; NONHUMAN; SPLEEN CELL; STANDARD; TECHNIQUE;

ANIMALS; B-LYMPHOCYTES; BIOLOGICAL MARKERS; CELL SURVIVAL; COLORING AGENTS; DANSYL COMPOUNDS; FEMALE; FLOW CYTOMETRY; LYMPHOCYTE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; NANOPARTICLES; SILOXANES; SPECTROMETRY, FLUORESCENCE; SPLEEN; T-LYMPHOCYTES;

EID: 69249226187     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2009.01.001     Document Type: Article

References (26)

1. Jamieson T., Bakhshi R., Petrova D., Pocock R., Imani M., and Seifalian A.M. Biological applications of quantum dots. Biomaterials. 28 (2007) 4717-4732
2. Li Z.B., Cai W., and Chen X. Semiconductor quantum dots for in vivo imaging. J Nanosci Nanotechnol. 7 (2007) 2567-2581
3. Liu W., Choi H.S., Zimmer J.P., Tanaka E., Frangioni J.V., and Bawendi M. Compact cysteine-coated CdSe(ZnCdS) quantum dots for in vivo applications. J Am Chem Soc. 129 (2007) 14530-14531
4. Michalet X., Pinaud F.F., Bentolila L.A., Tsay J.M., Doose S., Li J.J., et al. Quantum dots for live cells, in vivo imaging, and diagnostics. Science. 307 (2005) 538-544
5. Rogach A.L., Franzl T., Klar T.A., Feldmann J., Gaponik N., Lesnyak V., et al. Aqueous synthesis of thiol-capped CdTe nanocrystals: state-of-the-art. J Phys Chem C. 111 (2007) 14628-14637
6. Susumu K., Uyeda H.T., Medintz I.L., Pons T., Delehanty J.B., and Mattoussi H. Enhancing the stability and biological functionalities of quantum dots via compact multifunctional ligands. J Am Chem Soc. 129 (2007) 13987-13996
7. Burns A., Ow H., and Wiesner U. Fluorescent core-shell silica nanoparticles: towards "Lab on a Particle" architectures for nanobiotechnology. Chem Soc Rev. 35 (2006) 1028-1042
8. Burns A., Sengupta P., Zedayko T., Baird B., and Wiesner U. Core/shell fluorescent silica nanoparticles for chemical sensing: towards single-particle laboratories. Small. 2 (2006) 723-726
9. Senarath-Yapa M.D., Phimphivong S., Coym J.W., Wirth M.J., Aspinwall C.A., and Saavedra S.S. Preparation and characterization of poly(lipid)-coated, fluorophore-doped silica nanoparticles for biolabeling and cellular imaging. Langmuir. 23 (2007) 12624-12633
10. Smith J.E., Medley C.D., Tang Z., Shangguan D., Lofton C., and Tan W. Aptamer-conjugated nanoparticles for the collection and detection of multiple cancer cells. Anal Chem. 79 (2007) 3075-3082
11. Yao G., Wang L., Wu Y., Smith J., Xu J., Zhao W., et al. FloDots: luminescent nanoparticles. Anal Bioanal Chem. 385 (2006) 518-524
12. Parks C.G., Conrad K., and Cooper G.S. Occupational exposure to crystalline silica and autoimmune disease. Environ Health Perspect. 107 Suppl 5 (1999) 793-802
13. Shanklin D.R., and Smalley D.L. The immunopathology of siliconosis. History, clinical presentation, and relation to silicosis and the chemistry of silicon and silicone. Immunol Res 18 (1998) 125-173
14. Balbus J.M., Maynard A.D., Colvin V.L., Castranova V., Daston G.P., Denison R.A., et al. Meeting report: hazard assessment for nanoparticles-report from an interdisciplinary workshop. Environ Health Perspect. 115 (2007) 1654-1659
15. Li Z., Hulderman T., Salmen R., Chapman R., Leonard S.S., Young S.H., et al. Cardiovascular effects of pulmonary exposure to single-wall carbon nanotubes. Environ Health Perspect. 115 (2007) 377-382
16. Limbach L.K., Wick P., Manser P., Grass R.N., Bruinink A., and Stark W.J. Exposure of engineered nanoparticles to human lung epithelial cells: influence of chemical composition and catalytic activity on oxidative stress. Environ Sci Technol. 41 (2007) 4158-4163
17. Phan J.H., Young A.N., and Wang M.D. Selecting clinically-driven biomarkers for cancer nanotechnology. Conf Proc IEEE Eng Med Biol Soc. 1 (2006) 3317-3320
18. Monteiller C., Tran L., MacNee W., Faux S., Jones A., Miller B., et al. The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area. Occup Environ Med. 64 (2007) 609-615
19. Ryman-Rasmussen J.P., Riviere J.E., and Monteiro-Riviere N.A. Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes. J Invest Dermatol. 127 (2007) 143-153
20. Wörle-Knirsch J.M., Pulskamp K., and Krug H.F. Oops they did it again! Carbon nanotubes hoax scientists in viability assays. Nano Lett. 6 (2006) 1261-1268
21. Cho S.J., Maysinger D., Jain M., Roder B., Hackbarth S., and Winnik F.M. Long-term exposure to CdTe quantum dots causes functional impairments in live cells. Langmuir. 23 (2007) 1974-1980
22. Porter A.E., Gass M., Muller K., Skepper J.N., Midgley P.A., and Welland M. Direct imaging of single-walled carbon nanotubes in cells. Nat Nanotechnol. 2 (2007) 713-717
23. Fuller J.E., Zugates G.T., Ferreira L.S., Ow H.S., Nguyen N.N., Wiesner U.B., and Langer R.S. Intracellular delivery of core-shell fluorescent silica nanoparticles. Biomaterials 29 (2008) 1526-1532
24. Kim S., Ohulchanskyy T.Y., Pudavar H.E., Pandey R.K., and Prasad P.N. Organically modified silica nanoparticles co-encapsulating photosensitizing drug and aggregation-enhanced two-photon absorbing fluorescent dye aggregates for two-photon photodynamic therapy. J Am Chem Soc. 129 (2007) 2669-2675
25. Sertchook H., Elimelech H., and Avnir D. Composite particles of silica/poly(dimethylsiloxane). Chem Mater. 17 (2005) 4711-4716
26. Kruisbeek A.M. Isolation of mouse mononuclear cells. In: Coligan J.E., Bierer B., Margulies D.H., Shevach E.M., Strober W., Coico R., et al. (Eds). Current protocols in immunology (2000), Wiley, New York Unit 3.1