Heat shock protein 60: Evidence for receptor-mediated induction of proinflammatory mediators during adipocyte differentiation

FEBS Letters

Volumn 583, Issue 17, 2009, Pages 2877-2881

  Gülden, Elke ^a   Märker, Tina ^a   Kriebel, Jennifer ^a   Kolb Bachofen, Victoria ^b   Burkart, Volker ^a   Habich, Christiane ^a  

^a LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Adipocyte; Chemokine; Cytokine; Heat shock protein 60; Inflammation; Obesity

Indexed keywords

CXCL1 CHEMOKINE; HEAT SHOCK PROTEIN 60; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE RELEASE; INFLAMMATION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN BINDING;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CHAPERONIN 60; HUMANS; INFLAMMATION MEDIATORS; MICE; SIGNAL TRANSDUCTION;

EID: 69249223074     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.07.049     Document Type: Article

References (20)

1. Charrière G., Cousin B., Arnaud E., André M., Bacou F., Pénicaud L., and Casteilla L. Preadipocyte conversion to macrophage. Evidence of plasticity. J. Biol. Chem. 278 (2003) 9850-9855
2. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 115 (2005) 911-919
3. Wellen K.E., and Hotamisligil G.S. Inflammation, stress, and diabetes. J. Clin. Invest. 115 (2005) 1111-1119
4. Gülden E., Mollérus S., Brüggemann J., Burkart V., and Habich C. Heat shock protein 60 induces inflammatory mediators in mouse adipocytes. FEBS Lett. 582 (2008) 2731-2736
5. Fink A.L. Chaperone-mediated protein folding. Physiol. Rev. 79 (1999) 425-449
6. Habich C., and Burkart V. Heat shock protein 60: regulatory role on innate immune cells. Cell. Mol. Life Sci. 64 (2007) 742-751
7. Avram M.M., Avram A.S., and James W.D. Subcutaneous fat in normal and diseased states 3. Adipogenesis: from stem cell to fat cell. J. Am. Acad. Dermatol. 56 (2007) 472-492
8. Wada T., Shimba S., and Tezuka M. Transcriptional regulation of the hypoxia inducible factor-2alpha (HIF-2alpha) gene during adipose differentiation in 3T3-L1 cells. Biol. Pharm. Bull. 29 (2006) 49-54
9. Hauner H. Secretory factors from human adipose tissue and their functional role. Proc. Nutr. Soc. 64 (2005) 163-169
10. Macaulay S.L., and Larkins R.G. Impaired insulin action in adipocytes of New Zealand obese mice: a role for postbinding defects in pyruvate dehydrogenase and insulin mediator activity. Metabolism 37 (1988) 958-965
11. Habich C., Baumgart K., Kolb H., and Burkart V. The receptor for heat shock protein 60 on macrophages is saturable, specific, and distinct from receptors for other heat shock proteins. J. Immunol. 168 (2002) 569-576
12. Student A.K., Hsu R.Y., and Lane M.D. Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. J. Biol. Chem. 255 (1980) 4745-4750
13. Hotamisligil G.S. Inflammation and metabolic disorders. Nature 444 (2006) 860-867
14. Chen W., Syldath U., Bellmann K., Burkart V., and Kolb H. Human 60-kDa heat-shock protein: a danger signal to the innate immune system. J. Immunol. 162 (1999) 3212-3219
15. Weisberg S.P., McCann D., Desai M., Rosenbaum M., Leibel R.L., and Ferrante A.W. Obesity is associated with macrophage accumulation in adipose tissue. J. Clin. Invest. 112 (2003) 1796-1808
16. Bastard J.P., Maachi M., Lagathu C., Kim M.J., Caron M., Vidal H., Capeau J., and Feve B. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur. Cytokine Netw. 17 (2006) 4-12
17. de Ferranti S., and Mozaffarian D. The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. Clin. Chem. 54 (2008) 945-955
18. Habich C., Kempe K., van der Zee R., Rümenapf R., Akiyama H., Kolb H., and Burkart V. Heat shock protein 60: Specific binding of lipopolysaccharide. J. Immunol. 174 (2005) 1298-1305
19. Hoch M., Eberle A.N., Peterli R., Peters T., Seboek D., Keller U., Müller B., and Linscheid P. LPS induces interleukin-6 and interleukin-8 but not tumor necrosis factor-alpha in human adipocytes. Cytokine 41 (2008) 29-37
20. Bäck K., and Arnqvist H.J. Changes in insulin and IGF-I receptor expression during differentiation of human preadipocytes. Growth Horm. IGF Res. 19 (2009) 101-111