Intraoperative field flooding with warm humidified CO2 may help to prevent adhesion formation after open surgery

Medical Hypotheses

Volumn 73, Issue 4, 2009, Pages 521-523

  Persson, Mikael ^a   van der Linden, Jan ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; REACTIVE OXYGEN METABOLITE;

AMBIENT AIR; ARTICLE; DESICCATION; HUMAN; HYPOXIA; INDUCED HYPOTHERMIA; LAPAROSCOPIC SURGERY; NONHUMAN; OXIDATIVE STRESS; OXYGEN TISSUE LEVEL; PERITONEUM ADHESION; PEROPERATIVE CARE; PNEUMOPERITONEUM; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RISK REDUCTION; SCAR; SCAR FORMATION; WOUND INFECTION;

CARBON DIOXIDE; HUMANS; HYPOTHERMIA, INDUCED; IRRIGATION; MODELS, BIOLOGICAL; TISSUE ADHESIONS;

BACTERIA (MICROORGANISMS);

EID: 69249202353     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2009.06.009     Document Type: Article

References (31)

1. The Practice Committee of the American Society for Reproductive Medicine. Pathogenesis, consequences, and control of peritoneal adhesions in gynecologic surgery. Fertil Steril 90 (2008) S144-S149
2. Parker M.C., Wilson M.S., van Goor H., Moran B.J., Jeekel J., Duron J.J., et al. Adhesions and colorectal surgery - call for action. Colorectal Dis 9 Suppl. 2 (2007) 66-72
3. Ellis H., Moran B.J., Thompson J.N., Parker M.C., Wilson M.S., Menzies D., et al. Adhesion-related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study. Lancet 353 (1999) 1476-1480
4. Ray N.F., Denton W.G., Thamer M., Henderson S.C., and Perry S. Abdominal adhesiolysis: inpatient care and expenditures in the United States in 1994. J Am Coll Surg 186 (1998) 1-9
5. Ryan G.B., Grobety J., and Majno G. Mesothelial injury and recovery. Am J Pathol 71 (1973) 93-112
6. Nkere U.U., Whawell S.A., Sarraf C.E., Schofield J.B., Thompson J.N., and Taylor K.M. Perioperative histologic and ultrastructural changes in the pericardium and adhesions. Ann Thorac Surg 58 (1994) 437-444
7. Tsuchiya M., Sato E.F., Inoue M., and Asada A. Open abdominal surgery increases intraoperative oxidative stress: can it be prevented?. Anesth Analg 107 (2008) 1946-1952
8. Binda M.M., Molinas C.R., and Koninckx P.R. Reactive oxygen species and adhesion formation: clinical implications in adhesion prevention. Hum Reprod 18 (2003) 2503-2507
9. 2 insufflation on the number and behavior of air microemboli in open-heart surgery: a randomized clinical trial. Circulation 109 (2004) 1127-1132
10. Binda M.M., Molinas C.R., Hansen P., and Koninckx P.R. Effect of desiccation and temperature during laparoscopy on adhesion formation in mice. Fertil Steril 86 (2006) 166-175
11. Persson M., and van der Linden J. Can wound desiccation be averted during cardiac surgery? An experimental study. Anesth Analg 100 (2005) 315-320
12. Persson M., Elmqvist H., and van der Linden J. Topical humidified carbon dioxide to keep the open surgical wound warm: the greenhouse effect revisited. Anesthesiology 101 (2004) 945-949
13. 2 prevents hypothermia, peritoneal injury, and intra-abdominal adhesions during prolonged laparoscopic insufflations. J Surg Res 151 (2009) 40-47
14. 2 insufflation can decrease the risk of surgical site infection. Med Hypotheses 71 (2008) 8-13
15. Persson M., and van der Linden J. Wound ventilation with carbon dioxide: a simple method to prevent direct airborne contamination during cardiac surgery?. J Hosp Infect 56 (2004) 131-136
16. Persson M., Svenarud P., Flock J.I., and van der Linden J. Carbon dioxide inhibits the growth rate of Staphylococcus aureus at body temperature. Surg Endosc 19 (2005) 91-94
17. Sheffield C.W., Sessler D.I., and Hopf H.W. M. S, Moayeri A, Hunt TK, West JM. Centrally and locally mediated thermoregulatory responses alter subcutaneous oxygen tension. Wound Rep Reg 4 (1996) 339-345
18. Hopf H.W., Hunt T.K., West J.M., Blomquist P., Goodson III W.H., Jensen J.A., et al. Wound tissue oxygen tension predicts the risk of wound infection in surgical patients. Arch Surg 132 (1997) 997-1004
19. Kurz A., Sessler D.I., and Lenhardt R. Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of wound infection and temperature group. N Engl J Med 334 (1996) 1209-1215
20. Elkelani O.A., Binda M.M., Molinas C.R., and Koninckx P.R. Effect of adding more than 3% oxygen to carbon dioxide pneumoperitoneum on adhesion formation in a laparoscopic mouse model. Fertil Steril 82 (2004) 1616-1622
21. Persson M., Svenarud P., and van der Linden J. What is the optimal device for carbon dioxide deairing of the cardiothoracic wound and how should it be positioned?. J Cardiothorac Vasc Anesth 18 (2004) 180-184
22. Molinas C.R., Mynbaev O., Pauwels A., Novak P., and Koninckx P.R. Peritoneal mesothelial hypoxia during pneumoperitoneum is a cofactor in adhesion formation in a laparoscopic mouse model. Fertil Steril 76 (2001) 560-567
23. Bourdel N., Matsuzaki S., Bazin J.E., Pouly J.L., Mage G., and Canis M. Peritoneal tissue-oxygen tension during a carbon dioxide pneumoperitoneum in a mouse laparoscopic model with controlled respiratory support. Hum Reprod 22 (2007) 1149-1155
24. Matsuzaki S., Canis M., Bazin J.E., Darcha C., Pouly J.L., and Mage G. Effects of supplemental perioperative oxygen on post-operative abdominal wound adhesions in a mouse laparotomy model with controlled respiratory support. Hum Reprod 22 (2007) 2702-2706
25. Binda MM, Koninckx PR. Prevention of adhesion formation in a laparoscopic mouse model should combine local treatment with peritoneal cavity conditioning. Hum Reprod 2009; Epub ahead of print.
26. Binda M.M., Molinas C.R., Mailova K., and Koninckx P.R. Effect of temperature upon adhesion formation in a laparoscopic mouse model. Hum Reprod 19 (2004) 2626-2632
27. Sessler D.I. Complications and treatment of mild hypothermia. Anesthesiology 95 (2001) 531-543
28. Persson M., and van der Linden J. De-airing of a cardiothoracic wound cavity model with carbon dioxide: theory and comparison of a gas diffuser with conventional tubes. J Cardiothorac Vasc Anesth 17 (2003) 329-335
29. 2-pneumoperitoneum: the role of design, methodology and animal models. Hum Reprod 2009; Epub ahead of print.
30. Persson M., and van der Linden J. A simple system for intraoperative antiseptic wound ventilation. J Hosp Infect 55 (2003) 152-153
31. Persson M., and van der Linden J. The potential use of carbon dioxide as a carrier gas for drug delivery into open wounds. Med Hypotheses 72 (2009) 121-124