Chromatographic/mass spectrometric method for the estimation of itraconazole and its metabolite in human plasma: Application to a bioequivalence study

Arzneimittel-Forschung/Drug Research

Volumn 59, Issue 8, 2009, Pages 422-428

  Grabowski, Tomasz ^a   Świerczewska, Anna ^a   Borucka, Beata ^a   Sawicka, Renata ^a   Sasinowska Motyl, Małgorzata ^b   Gumułka, Stanisław Witold ^b  

^a Centre of Pharmacokinetics Research FILAB   (Poland)

^b MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Antifungal drugs; CAS 112559 91 8; CAS 84625 61 6; HPLC mass spectrometry; Hydroxyitraconazole, bioavailability; Itraconazole, bioavailability; Itrakonazol Genexo

Indexed keywords

HYDROXYITRACONAZOLE; ITRACONAZOLE; TERCONAZOLE;

ACCURACY; ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG STABILITY; FOOD AND DRUG ADMINISTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; QUALITY CONTROL; VALIDATION STUDY;

EID: 69249155006     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296418     Document Type: Article

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