Simultaneous itraconazole bioequivalence assessment and CYP3A phenotyping in South American subjects

International Journal of Clinical Pharmacology and Therapeutics

Volumn 43, Issue 2, 2005, Pages 109-116

  Estevez Carrizo, F E ^a   Ruiz, S ^b   Bellocq, B ^b   Leal, C ^b   Siri, M T ^b   del Campo, M J ^b  

^a UNIVERSIDAD DE MONTEVIDEO   (Uruguay)

^b AllQuimia BioResearch Lab   (Uruguay)

Author keywords

Bioequivalence; CYP3A; Itraconazol; Phenotyping; South Americans

Indexed keywords

6BETA HYDROXYHYDROCORTISONE; CYTOCHROME P450 3A; HYDROCORTISONE; ITRACONAZOLE; TRACONAL;

ADULT; AREA UNDER THE CURVE; ARTICLE; BIOASSAY; BIOEQUIVALENCE; BLOOD ANALYSIS; BLOOD SAMPLING; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION FUNCTION; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; ENZYME SUBSTRATE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE URINE LEVEL; INGESTION; MALE; METABOLIC RATE; NORMAL HUMAN; OPEN STUDY; PHENOTYPE; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; SOUTH AMERICA; STATISTICAL SIGNIFICANCE; URINALYSIS; URUGUAY; VALIDATION PROCESS; VENOUS BLOOD;

EID: 14544291996     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/CPP43109     Document Type: Article

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