Diallyl trisulfide reverses drug resistance and lowers the ratio of CD133+ cells in conjunction with methotrexate in a human osteosarcoma drug-resistant cell subline

Molecular Medicine Reports

Volumn 2, Issue 2, 2009, Pages 245-252

  Li, Ji ^a   Liu, Wei ^b   Zhao, Kongbo ^c   Zhang, Yongkui ^b   Li, Xin ^a   Yang, Qiang ^a   Li, Zhenfeng ^a   Li, Jianmin ^a  

^a SHANDONG UNIVERSITY   (China)

^b Shandong Traditional Chinese Medicine University   (China)

^c LINYI PEOPLE'S HOSPITAL   (China)

Author keywords

CD133; Diallyl trisulfide; Osteosarcoma; P glycoprotein; Tumor stem cells

Indexed keywords

CD133 ANTIGEN; CISPLATIN; DIALLYL TRISULFIDE; DOXORUBICIN; EPIRUBICIN; GLYCOPROTEIN P; METHOTREXATE;

ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; OSTEOSARCOMA; PROTEIN EXPRESSION; SARCOMA CELL;

EID: 69249145631     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr_00000091     Document Type: Article

References (21)

1. Malayeri R, Filipits M, Suchomel RW, Zöchbauer S, Lechner K and Pirker R: Multidrug resistance in leukemias and its reversal. Leuk Lymphoma 23: 451-458, 1996. (Pubitemid 27029655)
2. Gomes CM, Van Paassen H, Romeo S, Welling MM, Feitsma RI, Abrunhosa AJ, Botelho MF, Hogendoorn PC, Pauwels E and Cleton-Jansen AM: Multidrug resistance mediated by ABC transporters in osteosarcoma cell line: mRNA analysis and functional radiotracer studies. Nucl Med Biol 33: 831-840, 2006. (Pubitemid 44512136)
3. Ma S, Chan KW, Hu L, Lee TK, Wo JY, Ng IO, Zheng BJ and Guan XY: Identification and characterization of tumorigenic liver cancer stem/progenitor cells. Gastroenterology 132: 2542-2556, 2007. (Pubitemid 46890873)
4. + hepatocellular carcinoma cells as cancer stem/progenitor cells. Biochem Biophys Res Commun 351: 820-824, 2006.
5. Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C and De Maria R: Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115, 2007. (Pubitemid 46067311)
6. Khanum F, Anilakumar KR and Viswanathan KR: Anticarcinogenic properties of garlic: a review. Crit Rev Food Sci Nutr 44: 479-488, 2004.
7. Arora A, Seth K and Shukla Y: Reversal of P-glycoprotein-mediated multidrug resistance by diallyl sulfide in K562 leukemic cells and in mouse liver. Carcinogenesis 25: 941-949, 2004. (Pubitemid 38886080)
8. Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD and Dirks PB: Identification of human brain tumour initiating cells. Nature 432: 396-401, 2004. (Pubitemid 39551674)
9. O'Brien CA, Pollett A, Gallinger S and Dick JE: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445: 106-110, 2007. (Pubitemid 46067310)
10. Imanishi T, Abe Y, Suto R, Higaki S, UeyamaY, Nakamura M, Tamaoki N, Fukuda H and Imai N: Expression of the human multidrug resistance gene (MDR1) and prognostic correlation in human osteogenic sarcoma. Tokai J Exp Clin Med 19: 39-46, 1994.
11. Suto R, Abe Y, Nakamura M, Ohnishi Y, Yoshimura M, Lee YH, Imanishi T, Yamazaki H, Kijima H, Tokunaga T, Oshika Y, Hiraoka N, Tamaoki N, Fukuda H and Ueyama Y: Multidrug resistance mediated by overexpression of P-glyco-protein in human osteosarcoma in vivo. Int J Oncol 12: 287-291, 1998. (Pubitemid 28064849)
12. Jakubíková J and Sedlák J: Garlic-derived organosulfides induce cytotoxicity, apoptosis, cell cycle arrest and oxidative stress in human colon carcinoma cell lines. Neoplasma 53: 191-199, 2006.
13. Das A, Banik NL and Ray SK: Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cysteine proteases for apoptosis in human glioblastoma T98G and U87MG cells. Cancer 110: 1083-1095, 2007. (Pubitemid 47312875)
14. Kim YA, Xiao D, Xiao H, Powolny AA, Lew KL, Reilly ML, Zeng Y, Wang Z and Singh SV: Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak. Mol Cancer Ther 6: 1599-1609, 2007. (Pubitemid 46954027)
15. Bodey B, Taylor CR, Siegel SE and Kaiser HE: Immunocytochemical observation of multidrug resistance (MDR) p170 glycoprotein expression in human osteosarcoma cells. The clinical significance of MDR protein overexpression. Anticancer Res 15: 2461-2468, 1995.
16. Chan HS, Grogan TM, Haddad G, DeBoer G and Ling V: P-glycoprotein expression: critical determinant in the response to osteosarcoma chemotherapy. J Natl Cancer Inst 89: 1706-1715, 1997. (Pubitemid 27508195)
17. Wunder JS, Bull SB, Aneliunas V, Lee PD, Davis AM, Beauchamp CP, Conrad EU, Grimer RJ, Healey JH, Rock MJ, Bell RS and Andrulis IL: MDR1 gene expression and outcome in osteosarcoma: a prospective, multicenter study. J Clin Oncol 18: 2685-2694, 2000. (Pubitemid 30463550)
18. Shnyder SD, Hayes AJ, Pringle J and Archer CW: P-glycoprotein and metallothionein expression and resistance to chemotherapy in osteosarcoma. Br J Cancer 78: 757-759, 1998. (Pubitemid 28418308)
19. Chaudhary PM and Roninson IB: Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 66: 85-94, 1991.
20. Goodell MA, Brose K, Paradis G, Conner AS and Mulligan RC: Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 183: 1797 - 1806, 1996.
21. Sato T, Laver JH and Ogawa M: Reversible expression of CD34 by murine hematopoietic stem cells. Blood 94: 2548-2554, 1999. (Pubitemid 29477281)