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Volumn 1, Issue 6, 2008, Pages 805-812

Discrepancies between in silico and in vitro data in the functional analysis of a breast cancer-associated polymorphism in the XRCC6/Ku70 gene

Author keywords

Alternative promoter; Ku70; Non homologous end joining; Splicing; XRCC6

Indexed keywords

KU ANTIGEN; NUCLEIC ACID BINDING PROTEIN; UNCLASSIFIED DRUG; X RAY REPAIR CROSS COMPLEMENTING 6 PROTEIN;

EID: 69249137494     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr_00000032     Document Type: Article
Times cited : (2)

References (30)
  • 3
    • 0037011657 scopus 로고    scopus 로고
    • Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition
    • DOI 10.1038/sj.bjc.6600628
    • Baeyens A, Thierens H, Claes K, Poppe B, Messiaen L, De Ridder L and Vral A: Chromosomal radiosensitivity in breast cancer patients with a known or putative genetic predisposition. Br J Cancer 87: 1379-1385, 2002. (Pubitemid 36044311)
    • (2002) British Journal of Cancer , vol.87 , Issue.12 , pp. 1379-1385
    • Baeyens, A.1    Thierens, H.2    Claes, K.3    Poppe, B.4    Messiaen, L.5    De Ridder, L.6    Vral, A.7
  • 4
    • 16244418744 scopus 로고    scopus 로고
    • Chromosomal radiosensitivity in breast cancer patients: Influence of age of onset of the disease
    • Baeyens A, van den Broecke R, Makar A, Thierens H, De Ridder L and Vral A: Chromosomal radiosensitivity in breast cancer patients: Influence of age of onset of the disease. Oncol Rep 13: 347-353, 2005.
    • (2005) Oncol Rep , vol.13 , pp. 347-353
    • Baeyens, A.1    Van Den Broecke, R.2    Makar, A.3    Thierens, H.4    De Ridder, L.5    Vral, A.6
  • 5
    • 0029008814 scopus 로고
    • Abnormal radiosensitivity of lymphocytes from breast-cancer patients with excessive normal tissue-damage after radiotherapy - Chromosome-aberrations after low dose-rate irradiation
    • Jones L, Scott D, Cowan R and Roberts S: Abnormal radiosensitivity of lymphocytes from breast-cancer patients with excessive normal tissue-damage after radiotherapy - chromosome-aberrations after low dose-rate irradiation. Int J Radiat Biol 67: 519-528, 1995.
    • (1995) Int J Radiat Biol , vol.67 , pp. 519-528
    • Jones, L.1    Scott, D.2    Cowan, R.3    Roberts, S.4
  • 6
    • 0031975834 scopus 로고    scopus 로고
    • Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: A test for predisposition?
    • Scott, D, Barber J, Levine E, Burrill W and Roberts S: Radiationinduced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposition? Br J Cancer 77: 614-620, 1998. (Pubitemid 28059469)
    • (1998) British Journal of Cancer , vol.77 , Issue.4 , pp. 614-620
    • Scott, D.1    Barber, J.B.P.2    Levine, E.L.3    Burrill, W.4    Roberts, S.A.5
  • 8
    • 33847271255 scopus 로고    scopus 로고
    • Links between DNA double strand break repair and breast cancer: Accumulating evidence from both familial and nonfamilial cases
    • DOI 10.1016/j.canlet.2006.06.004, PII S0304383506004083
    • Ralhan R, Kaur J, Kreienberg R and Wiesmüller L: Links between DNA double strand break repair and breast cancer: accumulating evidence from both familial and nonfamilial cases. Cancer Lett 248: 1-17, 2007. (Pubitemid 46319342)
    • (2007) Cancer Letters , vol.248 , Issue.1 , pp. 1-17
    • Ralhan, R.1    Kaur, J.2    Kreienberg, R.3    Wiesmuller, L.4
  • 9
    • 18444363078 scopus 로고    scopus 로고
    • Breast cancer susceptibility and the DNA damage response
    • Dapic V, Carvalho MA and Monteiro AN: Breast cancer susceptibility and the DNA damage response. Cancer Control 12: 127-136, 2005. (Pubitemid 40647057)
    • (2005) Cancer Control , vol.12 , Issue.2 , pp. 127-136
    • Dapic, V.1    Carvalho, M.A.2    Monteiro, A.N.A.3
  • 11
    • 0033406137 scopus 로고    scopus 로고
    • Inherited genetic predisposition in breast cancer: A population-based perspective
    • Rebbeck T: Inherited genetic predisposition in breast cancer - a population-based perspective. Cancer 86 (Suppl S): 2493-2501, 1999. (Pubitemid 30007532)
    • (1999) Cancer , vol.86 , Issue.11 SUPPL. , pp. 2493-2501
    • Rebbeck, T.R.1
  • 12
    • 0037506012 scopus 로고    scopus 로고
    • Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: A multigenic study on cancer susceptibility
    • Fu Y, Yu J, Cheng T, Lou M, Hsu G, Wu C, Chen S, Wu H, Wu P and Shen C: Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: A multigenic study on cancer susceptibility. Cancer Res 63: 2440-2446, 2003. (Pubitemid 36605181)
    • (2003) Cancer Research , vol.63 , Issue.10 , pp. 2440-2446
    • Fu, Y.-P.1    Yu, J.-C.2    Cheng, T.-C.3    Lou, M.A.4    Hsu, G.-C.5    Wu, C.-Y.6    Chen, S.-T.7    Wu, H.-S.8    Wu, P.-E.9    Shen, C.-Y.10
  • 14
    • 3142695504 scopus 로고    scopus 로고
    • Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1
    • DOI 10.1158/0008-5472.CAN-04-0403
    • Bau D, Fu Y, Chen S, Cheng T, Yu J, Wu P and Shen C: Breast cancer risk and the DNA double-strand break end-joining capacity of nonhomologous end-joining genes are affected by BRCA1. Cancer Res 64: 5013-5019, 2004. (Pubitemid 38924550)
    • (2004) Cancer Research , vol.64 , Issue.14 , pp. 5013-5019
    • Bau, D.-T.1    Fu, Y.-P.2    Chen, S.-T.3    Cheng, T.-C.4    Yu, J.-C.5    Wu, P.-E.6    Shen, C.-Y.7
  • 15
    • 34548084240 scopus 로고    scopus 로고
    • DNA double-strand break repair capacity and risk of breast cancer
    • DOI 10.1093/carcin/bgm109
    • Bau D, Mau Y, Ding S, Wu P and Shen C: DNA double-strand break repair capacity and risk of breast cancer. Carcinogenesis 28: 1726-1730, 2007. (Pubitemid 47289034)
    • (2007) Carcinogenesis , vol.28 , Issue.8 , pp. 1726-1730
    • Bau, D.-T.1    Mau, Y.-C.2    Ding, S.-L.3    Wu, P.-E.4    Shen, C.-Y.5
  • 18
    • 34447335052 scopus 로고    scopus 로고
    • Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers
    • DOI 10.1080/15287390600974924, PII 780502468
    • Roy D, Cai Q, Felty Q and Narayan S: Estrogen-induced generation of reactive oxygen and nitrogen species, gene damage, and estrogen-dependent cancers. J Toxicol Environ Health B Crit Rev 10: 235-257, 2007. (Pubitemid 47057178)
    • (2007) Journal of Toxicology and Environmental Health - Part B: Critical Reviews , vol.10 , Issue.4 , pp. 235-257
    • Roy, D.1    Cai, Q.2    Felty, Q.3    Narayan, S.4
  • 19
    • 0141757494 scopus 로고    scopus 로고
    • Regulation and mechanisms of mammalian double-strand break repair
    • Valerie K and Povirk L: Regulation and mechanisms of mammalian double-strand break repair Oncogene 22: 5792-5812, 2003.
    • (2003) Oncogene , vol.22 , pp. 5792-5812
    • Valerie, K.1    Povirk, L.2
  • 20
    • 33747889722 scopus 로고    scopus 로고
    • Role of non-homologous end joining (NHEJ) in maintaining genomic integrity
    • DOI 10.1016/j.dnarep.2006.05.026, PII S1568786406001650, Mechanisms of Chromosomal Translocations
    • Burma S, Chen BP and Chen DJ: Role of non-homologous end joining in maintaining genomic integrity. DNA Repair 5: 1042-1048, 2006. (Pubitemid 44291616)
    • (2006) DNA Repair , vol.5 , Issue.9-10 , pp. 1042-1048
    • Burma, S.1    Chen, B.P.C.2    Chen, D.J.3
  • 22
    • 34548029985 scopus 로고    scopus 로고
    • Pterygium and genetic polymorphism of DNA double strand break repair gene Ku70/XRCC6
    • Tsai YY, Bau DT, Chiang CC, Cheng YW, Tseng SH and Tsai FJ: Pterygium and genetic polymorphism of DNA double strand break repair gene Ku70/XRCC6. Mol Vis 13: 1436-1440, 2007.
    • (2007) Mol Vis , vol.13 , pp. 1436-1440
    • Tsai, Y.Y.1    Bau, D.T.2    Chiang, C.C.3    Cheng, Y.W.4    Tseng, S.H.5    Tsai, F.J.6
  • 23
    • 0023651307 scopus 로고
    • RNA splice junctions of different classes of eukaryotes: Sequence statistics and functional implications in gene expression
    • Shapiro MB and Senapathy P: RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res 15: 7155-7174, 1987.
    • (1987) Nucleic Acids Res , vol.15 , pp. 7155-7174
    • Shapiro, M.B.1    Senapathy, P.2
  • 24
    • 0031880376 scopus 로고    scopus 로고
    • Information analysis of human splice site mutations
    • Rogan PK, Faux BM and Schneider TD: Information analysis of human splice site mutations. Hum Mutat 12: 153-171, 1998.
    • (1998) Hum Mutat , vol.12 , pp. 153-171
    • Rogan, P.K.1    Faux, B.M.2    Schneider, T.D.3
  • 26
    • 0026663296 scopus 로고
    • Splicing takes a holliday
    • Steitz JA: Splicing takes a holliday. Science 257: 888-889, 1992.
    • (1992) Science , vol.257 , pp. 888-889
    • Steitz, J.A.1
  • 30
    • 10144227763 scopus 로고    scopus 로고
    • Parathyroid hormone induces c-fos promoter activity in osteoblastic cells through phosphorylated cAMP response element (CRE)-binding protein binding to the major CRE
    • Pearman AT, Chou WY, Bergman KD, Pulumati MR and Partridge NC. Parathyroid hormone induces c-fos promoter activity in osteoblastic cells through phosphorylated cAMP response element (CRE)-binding protein binding to the major CRE. J Biol Chem 271: 25715-25721, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 25715-25721
    • Pearman, A.T.1    Chou, W.Y.2    Bergman, K.D.3    Pulumati, M.R.4    Partridge, N.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.