Resistin as a cardiovascular and atherosclerotic risk factor and uremic toxin

Seminars in Dialysis

Volumn 22, Issue 4, 2009, Pages 373-377

  Cohen, Gerald ^a   Hörl, Walter H ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

RESISTIN; RETN PROTEIN, HUMAN; TOXIN;

ARTICLE; ATHEROSCLEROSIS; DISORDERS OF CARBOHYDRATE METABOLISM; HUMAN; METABOLISM; PHYSIOLOGY; RISK FACTOR; UREMIA;

ATHEROSCLEROSIS; GLUCOSE METABOLISM DISORDERS; HUMANS; RESISTIN; RISK FACTORS; TOXINS, BIOLOGICAL; UREMIA;

EID: 69249137033     PISSN: 08940959     EISSN: 1525139X     Source Type: Journal    
DOI: 10.1111/j.1525-139X.2009.00583.x     Document Type: Article

References (39)

1. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA : The hormone resistin links obesity to diabetes. Nature 409 : 307 312, 2001
2. Yang RZ, Huang Q, Xu A, McLenithan JC, Eisen JA, Shuldiner AR, Alkan S, Gong DW : Comparative studies of resistin expression and phylogenomics in human and mouse. Biochem Biophys Res Commun 310 : 927 935, 2003
3. Curat CA, Wegner V, Sengenes C, Miranville A, Tonus C, Busse R, Bouloumie A : Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin. Diabetologia 49 : 744 747, 2006
4. Hu WL, Qian SB, Li JJ : Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin. Cytokine 40 : 201 206, 2007
5. Sheng CH, Di J, Jin Y, Zhang YC, Wu M, Sun Y, Zhang GZ : Resistin is expressed in human hepatocytes and induces insulin resistance. Endocrine 33 : 135 143, 2008
6. McTernan PG, Fisher FM, Valsamakis G, Chetty R, Harte A, McTernan CL, Clark PM, Smith SA, Barnett AH, Kumar S : Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes. J Clin Endocrinol Metab 88 : 6098 6106, 2003
7. Piestrzeniewicz K, Luczak K, Komorowski J, Maciejewski M, Jankiewicz Wika J, Goch JH : Resistin increases with obesity and atherosclerotic risk factors in patients with myocardial infarction. Metabolism 57 : 488 493, 2008
8. Iqbal N, Seshadri P, Stern L, Loh J, Kundu S, Jafar T, Samaha FF : Serum resistin is not associated with obesity or insulin resistance in humans. Eur Rev Med Pharmacol Sci 9 : 161 165, 2005
9. Axelsson J, Bergsten A, Qureshi AR, Heimburger O, Barany P, Lonnqvist F, Lindholm B, Nordfors L, Alvestrand A, Stenvinkel P : Elevated resistin levels in chronic kidney disease are associated with decreased glomerular filtration rate and inflammation, but not with insulin resistance. Kidney Int 69 : 596 604, 2006
10. Cohen G, Ilic D, Raupachova J, Hörl WH : Resistin inhibits essential functions of polymorphonuclear leukocytes. J Immunol 181 : 3761 3768, 2008
11. Yaturu S, Reddy RD, Rains J, Jain SK : Plasma and urine levels of resistin and adiponectin in chronic kidney disease. Cytokine 37 : 1 5, 2007
12. Diez JJ, Iglesias P, Fernandez-Reyes MJ, Aguilera A, Bajo MA, Alvarez-Fidalgo P, Codoceo R, Selgas R : Serum concentrations of leptin, adiponectin and resistin, and their relationship with cardiovascular disease in patients with end-stage renal disease. Clin Endocrinol (Oxf) 62 : 242 249, 2005
13. Taskapan MC, Taskapan H, Sahin I, Keskin L, Atmaca H, Ozyalin F : Serum leptin, resistin, and lipid levels in patients with end stage renal failure with regard to dialysis modality. Ren Fail 29 : 147 154, 2007
14. Malyszko J, Malyszko JS, Kozminski P, Pawlak K, Mysliwiec M : Elevated resistin is related to inflammation and residual renal function in haemodialysed patients. Nephrology (Carlton) 12 : 246 253, 2007
15. Nusken KD, Kratzsch J, Wienholz V, Stohr W, Rascher W, Dotsch J : Circulating resistin concentrations in children depend on renal function. Nephrol Dial Transplant 21 : 107 112, 2006
16. Pilz S, Weihrauch G, Seelhorst U, Wellnitz B, Winkelmann BR, Boehm BO, Marz W : Implications of resistin plasma levels in subjects undergoing coronary angiography. Clin Endocrinol (Oxf) 66 : 380 386, 2007
17. Risch L, Saely C, Hoefle G, Rein P, Langer P, Gouya G, Marte T, Aczel S, Drexel H : Relationship between glomerular filtration rate and the adipokines adiponectin, resistin and leptin in coronary patients with predominantly normal or mildly impaired renal function. Clin Chim Acta 376 : 108 113, 2007
18. Sunden-Cullberg J, Nystrom T, Lee ML, Mullins GE, Tokics L, Andersson J, Norrby-Teglund A, Treutiger CJ : Pronounced elevation of resistin correlates with severity of disease in severe sepsis and septic shock. Crit Care Med 35 : 1536 1542, 2007
19. Migita K, Maeda Y, Miyashita T, Kimura H, Nakamura M, Ishibashi H, Eguchi K : The serum levels of resistin in rheumatoid arthritis patients. Clin Exp Rheumatol 24 : 698 701, 2006
20. Larochelle J, Freiler J, Dice J, Hagan L : Plasma resistin levels in asthmatics as a marker of disease state. J Asthma 44 : 509 513, 2007
21. Anderson PD, Mehta NN, Wolfe ML, Hinkle CC, Pruscino L, Comiskey LL, Tabita-Martinez J, Sellers KF, Rickels MR, Ahima RS, Reilly MP : Innate immunity modulates adipokines in humans. J Clin Endocrinol Metab 92 : 2272 2279, 2007
22. Gerber M, Boettner A, Seidel B, Lammert A, Bar J, Schuster E, Thiery J, Kiess W, Kratzsch J : Serum resistin levels of obese and lean children and adolescents: biochemical analysis and clinical relevance. J Clin Endocrinol Metab 90 : 4503 4509, 2005
23. Mojiminiyi OA, Abdella NA : Associations of resistin with inflammation and insulin resistance in patients with type 2 diabetes mellitus. Scand J Clin Lab Invest 67 : 215 225, 2007
24. Banks WA, Willoughby LM, Thomas DR, Morley JE : Insulin resistance syndrome in the elderly: assessment of functional, biochemical, metabolic, and inflammatory status. Diabetes Care 30 : 2369 2373, 2007
25. Filippidis G, Liakopoulos V, Mertens PR, Kiropoulos T, Stakias N, Verikouki C, Patsidis E, Koukoulis G, Stefanidis I : Resistin serum levels are increased but not correlated with insulin resistance in chronic hemodialysis patients. Blood Purif 23 : 421 428, 2005
26. Hasegawa G, Ohta M, Ichida Y, Obayashi H, Shigeta M, Yamasaki M, Fukui M, Yoshikawa T, Nakamura N : Increased serum resistin levels in patients with type 2 diabetes are not linked with markers of insulin resistance and adiposity. Acta Diabetol 42 : 104 109, 2005
27. Tabara Y, Igase M, Osawa H, Makino H, Miki T, Kohara K : Resistin, glomerular filtration rate, and insulin resistance. Hypertension 51 : e11, 2008 author reply e12
28. Palanivel R, Maida A, Liu Y, Sweeney G : Regulation of insulin signalling, glucose uptake and metabolism in rat skeletal muscle cells upon prolonged exposure to resistin. Diabetologia 49 : 183 190, 2006
29. Graveleau C, Zaha VG, Mohajer A, Banerjee RR, Dudley-Rucker N, Steppan CM, Rajala MW, Scherer PE, Ahima RS, Lazar MA, Abel ED : Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action. J Biol Chem 280 : 31679 31685, 2005
30. Patel L, Buckels AC, Kinghorn IJ, Murdock PR, Holbrook JD, Plumpton C, Macphee CH, Smith SA : Resistin is expressed in human macrophages and directly regulated by PPAR gamma activators. Biochem Biophys Res Commun 300 : 472 476, 2003
31. Burnett MS, Lee CW, Kinnaird TD, Stabile E, Durrani S, Dullum MK, Devaney JM, Fishman C, Stamou S, Canos D, Zbinden S, Clavijo LC, Jang GJ, Andrews JA, Zhu J, Epstein SE : The potential role of resistin in atherogenesis. Atherosclerosis 182 : 241 248, 2005
32. Verma S, Li SH, Wang CH, Fedak PW, Li RK, Weisel RD, Mickle DA : Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation 108 : 736 740, 2003
33. Skilton MR, Nakhla S, Sieveking DP, Caterson ID, Celermajer DS : Pathophysiological levels of the obesity related peptides resistin and ghrelin increase adhesion molecule expression on human vascular endothelial cells. Clin Exp Pharmacol Physiol 32 : 839 844, 2005
34. Cohen G, Rudnicki M, Hörl WH : Uremic toxins modulate the spontaneous apoptotic cell death and essential functions of neutrophils. Kidney Int Suppl 78 : S48 S52, 2001
35. Delamaire M, Maugendre D, Moreno M, Le Goff MC, Allannic H, Genetet B : Impaired leucocyte functions in diabetic patients. Diabet Med 14 : 29 34, 1997
36. Geerlings SE, Hoepelman AI : Immune dysfunction in patients with diabetes mellitus (DM). FEMS Immunol Med Microbiol 26 : 259 265, 1999
37. Shah SV, Wallin JD, Eilen SD : Chemiluminescence and superoxide anion production by leukocytes from diabetic patients. J Clin Endocrinol Metab 57 : 402 409, 1983
38. Steppan CM, Wang J, Whiteman EL, Birnbaum MJ, Lazar MA : Activation of SOCS-3 by resistin. Mol Cell Biol 25 : 1569 1575, 2005
39. Moon B, Kwan JJ, Duddy N, Sweeney G, Begum N : Resistin inhibits glucose uptake in L6 cells independently of changes in insulin signaling and GLUT4 translocation. Am J Physiol Endocrinol Metab 285 : E106 E115, 2003