The effect of neutrophil elastase inhibitor on acute tubular necrosis after renal ischemia-reperfusion injury

Molecular Medicine Reports

Volumn 1, Issue 4, 2008, Pages 489-492

  Matsuyama, Masahide ^a   Hayama, Takuma ^a   Funao, Kiyoaki ^a   Naganuma, Toshihide ^a   Kawahito, Yutaka ^b   Sano, Hajime ^c   Chargui, Jamel ^d   Touraine, Jean Louis ^d   Nakatani, Tatsuya ^a   Yoshimura, Rikio ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

^d UNIVERSITÉ LYON 1   (France)

Author keywords

Acute tubular necrosis; Neutrophil elastase inhibitor; Renal ischemia reperfusion injury

Indexed keywords

CREATININE; LEUKOCYTE ELASTASE; SIVELESTAT;

ACUTE KIDNEY TUBULE NECROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CHEMISTRY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE CONTROL; ENDOTHELIUM CELL; IMMUNOHISTOCHEMISTRY; KIDNEY ISCHEMIA; KIDNEY TRANSPLANTATION; KIDNEY TUBULE CELL; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; STAINING; SURVIVAL RATE; UREA NITROGEN BLOOD LEVEL;

RATTUS;

EID: 69249122463     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.1.4.489     Document Type: Article

References (15)

1. Matsuyama M and Yoshimura R: Prospects of antisense oligodeoxynucleotides to alleviate renal ischaemia-reperfusion injury. Expert Opin Biol Ther 4: 1931-1937, 2004.
2. Matsuyama M, Yoshimura R, Akioka K, et al: Tissue factor antisense oligonucleotides prevent renal ischemia-reperfusion injury. Transplantation 76: 786-791, 2003. (Pubitemid 37140220)
3. Okajima K, Harada N, Uchiba M and Mori M: Neutrophil elastase contributes to the development of ischemia-reperfusion induced liver injury by decreasing endothelial production of prostacyclin in rats. Am J Physiol Gastrointest Liver Physiol 287: 1116-1123, 2004. (Pubitemid 39551840)
4. Kotake Y, Yamamoto M, Matsumoto M, Morisaki H and Takeda J: Sivelestat, a neutrophil elastase inhibitor, attenuates neutrophil priming after hepatoenteric ischemia in rabbits. Shock 23: 156-160, 2005. (Pubitemid 40222952)
5. Ueno M, Moriyama Y, Toda R, et al: Effect of neutrophil elastase inhibitor (ONO-5046 Na) on ischemia/reperfusion injury using left-sided heterotopic canine heart transplantation model. J Heart Lung Transplant 20: 889-896, 2001. (Pubitemid 32737523)
6. Ishikawa N, Oda M, Kawaguchi M, Tsunezuka Y and Watanabe G: The effect of a specific neutrophil elastase inhibitor (ONO-5046) in pulmonary ischemia-reperfusion injury. Transpl Int 16: 341-346, 2003. (Pubitemid 36733746)
7. Tomizawa N, Ohwada S, Ohya T, et al: The effects of a neutrophil elastase inhibitor (ONO-5046.Na) and neutrophil depletion using a granulotrap (G-1) column on lung reperfusion injury in dogs. J Heart Lung Transplant 18: 637-645, 1999. (Pubitemid 29361998)
8. Yamazaki T, Ooshima H, Usui A, Watanabe T and Yasuura K: Protective effects of ONO-5046.Na, a specific neutrophil elastase inhibitor, on postperfusion lung injury. Ann Thorac Surg 68: 2141-2146, 1999. (Pubitemid 30027838)
9. Soejima Y, Yanaga K, Nishizaki T, Yoshizumi T, Uchiyama H and Sugimachi K: Effect of specific neutrophil elastase inhibitor on ischemia-reperfusion injury in rat liver transplantation. J Surg Res 86: 150-154, 1999. (Pubitemid 29418501)
10. Tomizawa N, Ohwada S, Ohya T, Kawashima Y, Takeyoshi I and Morishita Y: The effect of neutrophil elastase inhibitor in hepatectomy with ischemia in dogs. J Surg Res 81: 230-237, 1999. (Pubitemid 29397816)
11. Yamaguchi Y, Akizuki E, Ichiguchi O, et al: Neutrophil elastase inhibitor reduces neutrophil chemoattractant production after ischemia-reperfusion in rat liver. Gastroenterology 112: 551-560, 1997. (Pubitemid 27078842)
12. Takayama M, Ishibashi M, Ishii H, Kuraki T, Nishida T and Yoshida M: Effect of neutrophil elastase inhibitor (ONO-5046) on lung injury after intestinal ischemia-reperfusion. J Appl Physiol 91: 1800-1807, 2001.
13. Matsuyama M, Yoshimura R, Hase T, et al: Study of cyclooxygenase- 2 in renal ischemia-reperfusion injury. Transplant Proc 37: 370-372, 2005. (Pubitemid 40459789)
14. Fitzgerald SM and Flinn S: Evaluating research studies using the analysis of variance (ANOVA): issues and interpretations. J Hand Ther 13: 56-60, 2000. (Pubitemid 30134138)
15. Janoff A: Elastase in tissue injury. Annu Rev Med 36: 207-216, 1985.