Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: Truncation of the core oligosaccharide leads to increased binding and sensitvity to polymyxin B

Journal of Biological Chemistry

Volumn 284, Issue 32, 2009, Pages 21738-21751

  Ortega, Ximena ^a   Silipo, Alba ^b   Saldfas, M Soledad ^a   Bates, Christa C ^a   Molinaro, Antonio ^b   Valvano, Miguel A ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL PEPTIDE; BACTERIAL CELLS; BARRIER PROPERTIES; BINDING ASSAYS; BURKHOLDERIA; CORE OLIGOSACCHARIDE; DIMETHYLAMINONAPHTHALENE; FUNCTIONAL GENES; HIGH RESISTANCE; IN-VITRO; INNER CORE; INTACT CELLS; L-ARABINOSE; LIPOPOLYSACCHARIDES; O-ANTIGEN; OUTER MEMBRANE; POLYMYXIN B;

ACIDS; BACTERIOLOGY; BIOCHEMISTRY; BIOSYNTHESIS; CELL MEMBRANES; GLUCOSE; LABELS; OLIGOSACCHARIDES; PEPTIDES; POLYSACCHARIDES;

AMINES;

3 DEOXY MANNO OCTULOSONIC ACID; 4 AMINO 4 DEOXYARABINOSE; BACTERIUM LIPOPOLYSACCHARIDE; CORE OLIGOSACCHARIDE; GLYCERO TALO OCTULOSONIC ACID; HEPTOSE; SUGAR ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BIOSYNTHESIS; BURKHOLDERIA CENOCEPACIA; CELL STRAIN K 562; CONTROLLED STUDY; GENE IDENTIFICATION; GENE LOCUS; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

ANIMALS; BURKHOLDERIA; CARBOHYDRATE SEQUENCE; CELL LINE; CLONING, MOLECULAR; DRUG RESISTANCE, BACTERIAL; HUMANS; LIPOPOLYSACCHARIDES; MICE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGOSACCHARIDES; PLASMIDS; POLYMYXIN B; PROTEIN BINDING;

BACTERIA (MICROORGANISMS); BURKHOLDERIA CENOCEPACIA;

EID: 69249111807     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.008532     Document Type: Article

References (56)

1. Mahenthiralingam, E., Urban, T. A., and Goldberg, J. B. (2005) Nat. Rev. Microbiol. 3, 144-156
2. Balandreau, J., Viallard, V., Cournoyer, B., Coenye, T., Laevens, S., and Vandamme, P. (2001) Appl. Environ. Microbiol. 67, 982-985
3. Aaron, S. D., Ferris, W., Henry, D. A., Speert, D. P., and Macdonald, N. E. (2000) Am. J. Respir. Crit. Care Med. 161, 1206-1212
4. Raetz, C. R., and Whitfield, C. (2002) Annu. Rev. Biochem. 71, 635-700
5. Caroff, M., and Karibian, D. (2003) Carbohydr. Res. 338, 2431-2447
6. Raetz, C. R., Reynolds, C. M., Trent, M. S., and Bishop, R. E. (2007) Annu. Rev. Biochem. 76, 295-329
7. Isshiki, Y., Kawahara, K., and Zähringer, U. (1998) Carbohydr. Res. 313, 21-27
8. Silipo, A., Molinaro, A., Cescutti, P., Bedini, E., Rizzo, R., Parrilli, M., and Lanzetta, R. (2005) Glycobiology 15, 561-570
9. Isshiki, Y., Zähringer, U., and Kawahara, K. (2003) Carbohydr. Res. 338, 2659-2666
10. Silipo, A., Molinaro, A., Ieranò, T., De Soyza, A., Sturiale, L., Garozzo, D., Aldridge, C., Corris, P. A., Khan, C. M., Lanzetta, R., and Parrilli, M. (2007) Chemistry 13, 3501-3511
11. Molinaro, A., De Castro, C., Lanzetta, R., Evidente, A., Parrilli, M., and Holst, O. (2002) J. Biol. Chem. 277, 10058-10063
12. Baird, R. M., Brown, H., Smith, A. W., and Watson, M. L. (1999) Immunopharmacology 44, 267-272
13. Devine, D. A. (2003) Mol. Immunol. 40, 431-443
14. Sahly, H., Schubert, S., Harder, J., Rautenberg, P., Ullmann, U., Schröder, J., and Podschun, R. (2003) Antimicrob. Agents Chemother. 47, 1739-1741
15. Loutet, S. A., Flannagan, R. S., Kooi, C., Sokol, P. A., and Valvano, M. A. (2006) J. Bacteriol. 188, 2073-2080
16. Burtnick, M. N., and Woods, D. E. (1999) Antimicrob. Agents Chemother. 43, 2648-2656
17. Cox, A. D., and Wilkinson, S. G. (1991) Mol. Microbiol. 5, 641-646
18. Mahenthiralingam, E., Coenye, T., Chung, J. W., Speert, D. P., Govan, J. R., Taylor, P., and Vandamme, P. (2000) J. Clin. Microbiol. 38, 910-913
19. Ortega, X. P., Cardona, S. T., Brown, A. R., Loutet, S. A., Flannagan, R. S., Campopiano, D. J., Govan, J. R., and Valvano, M. A. (2007) J. Bacteriol. 189, 3639-3644
20. Flannagan, R. S., Aubert, D., Kooi, C., Sokol, P. A., and Valvano, M. A. (2007) Infect. Immun. 75, 1679-1689
21. Flannagan, R. S., and Valvano, M. A. (2008) Microbiology 154, 643-653
22. Craig, F. F., Coote, J. G., Parton, R., Freer, J. H., and Gilmour, N. J. (1989) J. Gen. Microbiol. 135, 2885-2890
23. Figurski, D. H., and Helinski, D. R. (1979) Proc. Natl. Acad. Sci. U.S.A. 76, 1648-1652
24. Cohen, S. N., Chang, A. C., and Hsu, L. (1972) Proc. Natl. Acad. Sci. U.S.A. 69, 2110-2114
25. Marolda, C. L., Welsh, J., Dafoe, L., and Valvano, M. A. (1990) J. Bacteriol. 172, 3590-3599
26. Westphal, O., and Jann, K. (1965) in Methods in Carbohydrate Chemistry (Whistler, R. L., BeMiller, J. N., and Wolfrom, M. L., eds) pp. 83-91, Academic Press, New York
27. Schindler, P. R., and Teuber, M. (1975) Antimicrob. Agents Chemother. 8, 95-104
28. Bader, J., and Teuber, M. (1973) Z. Naturforsch. 28, 422-430
29. Moore, R. A., Bates, N. C., and Hancock, R. E. (1986) Antimicrob. Agents Chemother. 29, 496-500
30. Saldías, M. S., Lamothe, J., Wu, R., and Valvano, M. A. (2008) Infect. Immun. 76, 1059-1067
31. Holden, M. T., Seth-Smith, H. M., Crossman, L. C., Sebaihia, M., Bentley, S. D., Cerdeño-Tárraga, A. M., Thomson, N. R., Bason, N., Quail, M. A., Sharp, S., Cherevach, I., Churcher, C., Goodhead, I., Hauser, H., Holroyd, N., Mungall, K., Scott, P., Walker, D., White, B., Rose, H., Iversen, P., Mil-Homens, D., Rocha, E. P., Fialho, A. M., Baldwin, A., Dowson, C., Barrell, B. G., Govan, J. R., Vandamme, P., Hart, C. A., Mahenthiralingam, E., and Parkhill, J. (2009) J. Bacteriol. 191, 261-277
32. Reeves, P. R., Hobbs, M., Valvano, M. A., Skurnik, M., Whitfield, C., Coplin, D., Kido, N., Klena, J., Maskell, D., Raetz, C. R., and Rick, P. D. (1996) Trends Microbiol. 4, 495-503
33. Pérez, J. M., McGarry, M. A., Marolda, C. L., and Valvano, M. A. (2008) Mol. Microbiol. 70, 1424-1440
34. Ortega, X., Hunt, T. A., Loutet, S., Vinion-Dubiel, A. D., Datta, A., Choudhury, B., Goldberg, J. B., Carlson, R., and Valvano, M. A. (2005) J. Bacteriol. 187, 1324-1333
35. Birnbaum, G. I., Roy, R., Brisson, J. R., and Jennings, H. J. (1987) J. Carbohydr. Chem. 6, 17-39
36. Holst, O., Thomas-Oates, J. E., and Brade, H. (1994) Eur. J. Biochem. 222, 183-194
37. Bock, K., Vinogradov, E. V., Holst, O., and Brade, H. (1994) Eur. J. Biochem. 225, 1029-1039
38. Burns, J. L., Jonas, M., Chi, E. Y., Clark, D. K., Berger, A., and Griffith, A. (1996) Infect. Immun. 64, 4054-4059
39. Saini, L. S., Galsworthy, S. B., John, M. A., and Valvano, M. A. (1999) Microbiology 145, 3465-3475
40. Lamothe, J., Huynh, K. K., Grinstein, S., and Valvano, M. A. (2007) Cell. Microbiol. 9, 40-53
41. Via, L. E., Fratti, R. A., McFalone, M., Pagan-Ramos, E., Deretic, D., and Deretic, V. (1998) J. Cell Sci. 111, 897-905
42. Maloney, K. E., and Valvano, M. A. (2006) Infect. Immun. 74, 5477-5486
43. Holst, O. (2007) FEMS Microbiol. Lett. 271, 3-11
44. Loutet, S. A., Bartholdson, S. J., Govan, J. R. W., Campopiano, D. J., and Valvano, M. A. (2009) Microbiology 155, 2029-2039
45. Masoud, H., Perry, M. B., Brisson, J. R., Uhrin, D., Li, J., and Richards, J. C. (2009) Glycobiology 19, 462-471
46. Coenye, T., and Vandamme, P. (2003) Environ. Microbiol. 5, 719-729
47. Molinaro, A., Lindner, B., De Castro, C., Nolting, B., Silipo, A., Lanzetta, R., Parrilli, M., and Holst, O. (2003) Chemistry 9, 1542-1548
48. Gronow, S., Noah, C., Blumenthal, A., Lindner, B., and Brade, H. (2003) J. Biol. Chem. 278, 1647-1655
49. Moore, R. A., and Hancock, R. E. (1986) Antimicrob. Agents Chemother. 30, 923-926
50. Hoare, A., Bittner, M., Carter, J., Alvarez, S., Zaldívar, M., Bravo, D., Valvano, M. A., and Contreras, I. (2006) Infect. Immun. 74, 1555-1564
51. Marolda, C. L., Hauröder, B., John, M. A., Michel, R., and Valvano, M. A. (1999) Microbiology 145, 1509-1517
52. Arjcharoen, S., Wikraiphat, C., Pudla, M., Limposuwan, K., Woods, D. E., Sirisinha, S., and Utaisincharoen, P. (2007) Infect. Immun. 75, 4298-4304
53. Keith, K. E., Hynes, D. W., Sholdice, J. E., and Valvano, M. A. (2009) Microbiology 155, 1004-1015
54. Bylund, J., Burgess, L. A., Cescutti, P., Ernst, R. K., and Speert, D. P. (2006) J. Biol. Chem. 281, 2526-2532
55. Speert, D. P., Bond, M., Woodman, R. C., and Curnutte, J. T. (1994) J. Infect. Dis. 170, 1524-1531
56. Lefebre, M. D., and Valvano, M. A. (2002) Appl. Environ. Microbiol. 68, 5956-5964