High Matrix Metalloproteinase Activity Is a Hallmark of Periapical Granulomas

Journal of Endodontics

Volumn 35, Issue 9, 2009, Pages 1234-1242

  de Paula Silva, Francisco Wanderley Garcia ^a,c   D'Silva, Nisha J ^a,b   da Silva, Léa Assed Bezerra ^c   Kapila, Yvonne Lorraine ^a  

^a UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Extracellular matrix componenets; matrix metalloproteinases; periapical cyst; periapical granuloma; periodontal ligament

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B;

ARTICLE; BIOSYNTHESIS; CASE CONTROL STUDY; DIFFERENTIAL DIAGNOSIS; DNA MICROARRAY; ENZYME IMMUNOASSAY; ENZYMOLOGY; GENE EXPRESSION PROFILING; HUMAN; NEUTROPHIL; ODONTOGENIC CYST; PERIODONTAL LIGAMENT; TOOTH PERIAPICAL DISEASE;

CASE-CONTROL STUDIES; DIAGNOSIS, DIFFERENTIAL; GENE EXPRESSION PROFILING; HUMANS; IMMUNOENZYME TECHNIQUES; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEUTROPHILS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PERIAPICAL GRANULOMA; PERIODONTAL LIGAMENT; RADICULAR CYST;

EID: 69249110971     PISSN: 00992399     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joen.2009.06.008     Document Type: Article

References (41)

1. Kawashima N., and Stashenko P. Expression of bone-resorptive and regulatory cytokines in murine periapical inflammation. Arch Oral Biol 44 (1999) 55-66
2. Martón I.J., and Kiss C. Protective and destructive immune reactions in apical periodontitis. Oral Microbiol Immunol l15 (2000) 139-150
3. Liapatas S., Nakou M., and Rontogianni D. Inflammatory infiltrate of chronic periradicular lesions: an immunohistochemical study. Int Endod J 36 (2003) 464-471
4. Kabak S.L., Kabak Y.S., and Anischenko S.L. Light microscopic study of periapical lesions associated with asymptomatic apical periodontitis. Ann Anat 187 (2005) 185-194
5. Orstavik D., and Pitt Ford T.R. Essential endodontology: prevention and treatment of apical periodontitis (1998), Blackwell Science, Malden, MA
6. García C.C., Sempere F.V., Diago M.P., et al. The post-endodontic periapical lesion: histologic and etiopathogenic aspects. Med Oral Patol Oral Cir Bucal 12 (2007) E585-E590
7. Ricucci D., Mannocci F., and Pitt Ford T.R. A study of periapical lesions correlating the presence of a radiopaque lamina with histological findings. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101 (2006) 389-394
8. Cotti E., Campisi G., Ambu R., et al. Ultrasound real-time imaging in the differential diagnosis of periapical lesions. Int Endod J 36 (2003) 556-563
9. Simon J.H.S., Enciso E., Malfaz J.M., et al. Differential diagnosis of large periapical lesions using cone-beam computed tomography measurements and biopsy. J Endod 32 (2006) 833-837
10. Aggarwal V., Logani A., and Shah N. The evaluation of computed tomography scans and ultrasounds in the differential diagnosis of periapical lesions. J Endod 34 (2008) 1312-1315
11. Lin S.K., Chiang C.P., Hong C.Y., et al. Immunolocalization of interstitial collagenase (MMP-1) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in radicular cysts. J Oral Pathol Med 26 (1997) 458-463
12. Lin L.M., Huang G.T.J., and Rosenberg P.A. Proliferation of epithelial cell rests, formation of apical cysts, and regression of apical cysts after periapical wound healing. J Endod 33 (2007) 908-916
13. Lin L.M., Ricucci D., Lin J., et al. Nonsurgical root canal therapy of large cyst-like inflammatory periapical lesions and inflammatory apical cysts. J Endod 35 (2009) 607-615
14. Schulz M., von Arx T., Altermatt H.J., et al. Histology of periapical lesions obtained during apical surgery. J Endod 35 (2009) 634-642
15. Nair P.N., Sjögren U., Schumacher E., et al. Radicular cyst affecting a root-filled human tooth: a long-term posttreatment follow-up. Int Endod J 26 (1993) 225-233
16. Ramachandran Nair P.N., Pajarola G., and Schroeder H.E. Types and incidence of human periapical lesions obtained with extracted teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81 (1996) 93-102
17. Nair P.N.R. New perspectives on radicular cysts: do they heal?. Int Endod J 31 (1998) 155-160
18. Peters E., and Lau M. Histopathologic examination to confirm diagnosis of periapical lesions: a review. J Can Dent Assoc 69 (2003) 598-600
19. Woessner J.F. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J (1991) 2145-2154
20. Birkedal-Hansen H., Moore W.G., Bodden M.K., et al. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 4 (1993) 197-250
21. Krane S.M. Clinical Importance of metalloproteinases and their inhibitors. Ann N Y Acad Sci 732 (1994) 1-10
22. Sternlicht M.D., and Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 17 (2001) 463-516
23. Verma R.P., and Hansch C. Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. Bioorg Med Chem 15 (2007) 2223-2268
24. Teronen O., Salo T., Konttinen Y.T., et al. Identification and characterization of gelatinase / type IV collagenase in jaw cysts. J Oral Pathol Med 24 (1995) 78-84
25. Teronen O., Salo T., Laitinen J., et al. Characterization of interstitial collagenases in jaw cyst wall. Eur J Oral Sci 103 (1995) 141-147
26. Shin S.J., Lee J., Baek S.H., et al. Tissue levels of matrix metalloproteinases in pulps and periapical lesions. J Endod 28 (2002) 313-315
27. Wahlgren J., Salo T., Teronen O., et al. Matrix metalloproteinase-8 (MMP-8) in pulpal and periapical inflammation and periapical root-canal exudates. Int Endod J 35 (2002) 897-904
28. Leonardi R., Caltabiano R., and Loreto C. Collagenase-3 (MMP-13) is expressed in periapical lesions: na immunohistochemical study. Int Endod J 38 (2005) 297-301
29. Belmar M.J., Pabst C., Martínez B., et al. Gelatinolytic activity in gingival crevicular fluid from teeth with periapical lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105 (2008) 801-806
30. Morimoto T., Yamasaki M., Nakata K., et al. The expression of macrophage and neutrophil elastases in rat periradicular lesions. J Endod 34 (2008) 1072-1076
31. Vier F.V., and Figueiredo J.A.P. Prevalence of different periapical lesions associated with human teeth and their correlation with the presence and extension of apical external root resorption. Int Endod J 35 (2002) 710-719
32. Leeman M.F., Curran S., and Murray G.I. The structure, regulation, and function of human matrix metalloproteinase-13. Crit Rev Biochem Mol Biol 37 (2002) 149-166
33. Delzangles B., Boy-Lefevre M.L., and Forest N. Glycoproteins expression in apical pathologic tissues: clinical incidences. J Endod 23 (1997) 565-568
34. Carneiro E., Menezes R., Garlet G.P., et al. Expression analysis of matrix metalloproteinase-9 in epithelialized and nonepithelialized apical periodontitis lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107 (2009) 127-132
35. Fu X., Kassim S.Y., Parks W.C., et al. Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase. J Biol Chem 276 (2001) 41279-41287
36. Yamasaki M., Kumazawa M., Kohsaka T., et al. Effect of methotrexate-induced neutropenia on rat periapical lesion. Oral Surg Oral Med Oral Pathol 77 (1994) 655-661
37. Chakraborti S., Mandal M., Das S., et al. Regulation of matrix metalloproteinases: an overview. Mol Cell Biochem 253 (2003) 269-285
38. Lin S.K., Kok S.H., Kuo M.Y.P., et al. Sequential expressions of MMP-1, TIMP-1, IL-6 and COX-2 genes in induced periapical lesions in rats. Eur J Oral Sci 110 (2002) 246-253
39. Hong C.Y., Lin S.K., Kok S.H., et al. The role of lipopolysaccharide in infectious bone resorption of periapical lesion. J Oral Pathol Med 33 (2004) 162-169
40. Metzger Z., Belkin D., Kariv N., et al. Low-dose doxycycline inhibits bone resorption associated with apical periodontitis. Int Endod J 41 (2008) 303-309
41. Tjäderhane L., Hotakainen T., Kinnunen S., et al. The effect of chemical inhibition of matrix metalloproteinases on the size of experimentally induced apical periodontitis. Int Endod J 40 (2007) 282-289