Evaluation of the in vivo activity of different concentrations of Clerodendrum umbellatum Poir against Schistosoma mansoni infection in mice

African Journal of Traditional, Complementary and Alternative Medicines

Volumn 6, Issue 3, 2009, Pages 216-221

  Jatsa, H B ^a   Sock, E T Ngo ^b   Tchuente, L A Tchuem ^b,c   Kamtchouing, P ^b  

^a UNIVERSITY OF DOUALA   (Cameroon)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^c Centre for Schistosomiasis and Parasitology   (Cameroon)

Author keywords

Clerodendrum umbellatum; Faecal egg output; Mice; Schistosoma mansoni; Worm burden

Indexed keywords

ALKALOID; CLERODENDRUM UMBELLATUM EXTRACT; FLAVONOID; PLANT EXTRACT; PRAZIQUANTEL; SAPONIN; TANNIN; TRITERPENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CLERODENDRUM UMBELLATUM; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; FECES ANALYSIS; IN VIVO STUDY; LIVER WEIGHT; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PHYTOCHEMISTRY; PLANT LEAF; SCHISTOSOMIASIS MANSONI; SOLVENT EXTRACTION; SPLEEN WEIGHT; WORM INFECTION;

ANIMALS; CLERODENDRUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FECES; HUMANS; LIVER; MICE; MICE, INBRED BALB C; PARASITE EGG COUNT; PARASITIC SENSITIVITY TESTS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SCHISTOSOMICIDES;

EID: 69249092236     PISSN: 01896016     EISSN: 01896016     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Adjanohoun, J.E., Aboubakar, N., Dramane, K., Ebot, M.E., Ekpere, J.A., Enow-Orock, E.G., Focho, D., Gbile, Z.O., Kamanyi, A., Kamsu Kom, J., Keita, A., Mbenkum, T., Mbi, C.N., Mbiele, A.L., Mbome, I.L., Mubiru, N.K., Nancy, W.L., Nkongmeneck, B., Satabie, B., Sofowora, A., Tamze, V. and Wirmum, C.K. (1996). Traditional medicine and pharmacopoeia: contribution to ethnobotanical and floristic studies in Cameroon. CSTR/ OUA, CNPMS, Porto-Novo, 641p.
2. Asongalem, E.A., Foyet, H.S., Ekobo, H., Dimo, T. and Kamtchouing, P. (2004). Antiinflammatory, antipyretic and lack of central analgesic properties of Acanthus montanus. J. Ethnopharm., 95: 63-68.
3. Chae, S., Kim, J.S., Kang, K.A., Bu, H.D., Lee, Y., Hyun, J.W. and Kang, S.S. (2004). Antioxidant activity of Jionoside D from Clerodendron trichotomum. Biol. Pharm. Bull., 27: 1504-1508.
4. Chae, S., Kim, J.S., Kang, K.A., Bu, H.D., Lee, Y., Seo. Y.R., Hyun, J.W. and Kang, S.S. (2005). Antioxidant activity of isoacteoside from Clerodendron trichotomum. J. Toxicol. Environ. Health. A., 68: 389-400.
5. Cheek, M., Pollard, B.J., Darbyshire, I., Onana, J.M. and Wild, C. (2004). The plants of Kupe, Mwanenguba and the Bakossi mountains, Cameroon. Royal Botanic Gardens, Kew National Herbarium of Cameroon, 508p.
6. Cheever, A.W. and Anderson, L.A. (1971). Rate of destruction of Schistosoma mansoni eggs in tissues of mice. Am. J. Trop. Med. Hyg., 20: 62-68.
7. Choi, J.H., Whang, W.K. and Kim, H.J. (2004). Studies on the anti-inflammatory effects of Clerodendron trichotomum Thunberg leaves. Arch. Pharm. Res., 27: 189-193.
8. Cowan, M.M. (1999). Plant products as antimicrobial agents. Clin. Microbiol. Rev., 12: 564-582.
9. Devi, R., Banerjee, S.K., Sood, S., Dinda, A.K. and Maulik SK. (2005). Extract from Clerodendron colebrookianum Walp protects rat heart against oxidative stress induced by ischemic-reperfusion injury (IRI). Life Sci., 77: 2999-3009.
10. Duwall, R.H. and Dewitt, W.B. (1967). An improved perfusion technique for recovering adult schistosomes from laboratory animals. Am. J. Parasitol., 7: 293-297.
11. El-Ansary, A.K., Ahmed, S.A. and Aly, S.A. (2007). Antischistosomal and liver protective effects of Curcuma longa extract in Schistosoma mansoni infected mice. Ind. J. Exp. Biol., 45: 791-801.
12. El-Shenawy, N.S., Soliman, M.F. and Abdel-Nabi, I.M. (2006). Does Cleome droserifolia have anti-schistosomiasis mansoni activity? Rev. Inst. Med. Trop. S. Paulo., 48: 223-228.
13. Hamed, M.A. and Hetta, M.H. (2005). Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni. Mem. Inst. Oswaldo Cruz., 100: 771-778.
14. Ismail, M.M., Farghaly, A.M., Dyab, A.K., Afify, H.A. and El-Shafei, M.A. (2002). Resistance to praziquantel, effect of drug pressure and stability test. J. Egypt. Soc. Parasitol., 32: 589-600.
15. Katz, N., Marcos, P., Coelho, Z. and Pellegrino J. (1970). Evaluation of Kato's quantitative method through the recovery of S. i mansoni eggs. J. Parasitology, 56: 1032-1033.
16. Koko, W.S., Abdalla, H.S., Galal, M. and Khalid, H.S. (2005). Evaluation of oral therapy on mansomal schistosomiasis using single dose of Balanites aegyptiaca fruits and praziquantel. Fitoterapia, 76: 30-34.
17. Lescano, S.Z., Chieffi, P.P., Canhassi, R.R., Boulos, M. and Neto, V.A. (2004). Antischistosomal activity of artemether in experimental Schistosomiasis mansoni. Rev. Saude Publica, 38: 1-8.
18. Lyddiard, J.R., Whitfield, P.J. and Bartlett, A. (2002). Antischistosomal bioactivity of isoflavonoids from Millettia thonningii (Leguminosae). J. Parasitol., 88: 163-170.
19. Panthong, A., Kanjanapothi, D., Taesotikul, T., Wongcome, T. and Reutrakul V. (2003). Anti-inflammatory and antipyretic properties of Clerodendrum petasites S. Moore. J. Ethnopharmacol., 85: 151-156.
20. Perrett, S., Whitfield, P.J., Sanderson, L. and Bartlett, A. (1995). The plant molluscicide Millettia thonningii (Leguminosae) as a topical antischistosomal agent. J. Ethnopharmacol., 47: 49-54.
21. Rajlakshmi, D., Banerjee, S.K., Sood, S. and Maulik SK. (2003). In-vitro and in-vivo antioxidant activity of different extracts of the leaves of Clerodendron colebrookianum Walp in the rat. J. Pharm. Pharmacol., 55: 1681-1686.
22. Silva, L.M., Menezes, R.M., de Oliviera, S.A. and Andrade, Z.A. (2003). Chemotherapeutic effects on larval stages of Schistosoma mansoni during infection and reinfection of mice. Rev. Soc. Bras. Med. Trop., 36: 335-341.
23. Shuhua, X. and Catto, B. (1989). In vitro and In vivo studies of the effect of Artemether on Schistosoma mansoni. Antimicrob. Agents Chemother., 33: 1557-1562.
24. Tendler, M., Pinto, R.M., Oliveira, L.A., Gebara, G. and Katz, N. (1986). Schistosoma mansoni vaccination with adult worm antigens. Int. J. Parasitol., 16: 347-352. . Not cited in the text
25. Utzinger, J., Xiao, S.H., N'goran, E.K., Bergquist, R. and Tanner M. (2001). The potential of artemether for the control of schistosomiasis. Int. J. Parasitol., 31:1549-1562.
26. Weiner, M.A. (1994). Herbal antioxidants in clinical practice. J. Orthomol. Med., 9: 167-176.