Studies on the anti-inflammatory effects of Clerodendron trichotomum Thunberg Leaves

Archives of Pharmacal Research

Volumn 27, Issue 2, 2004, Pages 189-193

  Choi, Jung Ho ^a   Whang, Wan Kyun ^a   Kim, Hong Jin ^a  

^a Chung Ang University   (South Korea)

Author keywords

Anti inflammatory effect; Capillary permeability; PGE2

Indexed keywords

ACETIC ACID; CARRAGEENAN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; EVANS BLUE; INDOMETACIN; ISOENZYME; MEMBRANE PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PLANT EXTRACT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PTGS1 PROTEIN, MOUSE; PTGS1 PROTEIN, RAT;

ANIMAL; ARTICLE; BIOSYNTHESIS; CAPILLARY PERMEABILITY; CELL CULTURE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; CLERODENDRUM; COMPARATIVE STUDY; DRUG EFFECT; EDEMA; ENDOPLASMIC RETICULUM; ENZYMOLOGY; MACROPHAGE; MALE; METABOLISM; MOUSE; PLANT LEAF; RAT; SPRAGUE DAWLEY RAT;

ACETIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPILLARY PERMEABILITY; CARRAGEENAN; CELLS, CULTURED; CLERODENDRUM; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; EDEMA; ENDOPLASMIC RETICULUM; EVANS BLUE; INDOMETHACIN; ISOENZYMES; MACROPHAGES; MALE; MEMBRANE PROTEINS; MICE; PLANT EXTRACTS; PLANT LEAVES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 4644350532     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02980105     Document Type: Article

References (27)

1. DeWitt, D. and Smith, W. L., Primary structure of prostaglandin-G/H synthase from sheep vascular gland determined from the complementary-DNA sequence. Proc. Natl. Acad. Sci. USA, 85, 1412-1416 (1988).
2. DeWitt, D. and Smith W. L., Yes, but do they still get headaches? Cell, 83, 345-348 (1995).
3. Di, R. M., Giroud, J. P., and Willoughby, D. A., Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J. Pathol., 104, 15-29 (1971).
4. Erdem, Y. and Esra, K., Berberis crataegina DC root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. J. Ethnopharmacol., 79, 237-248 (2002).
5. Funk, C. D., Funk, L. B., Kennedy, M. E., Pong, A. S., and Fitzgerald, G. A., Human platelet erythroleukemia cell prostaglandin G/H synthase-cDNA cloning expression and gene chromosomal assignment. FASEB J., 5, 2304-2312 (1991).
6. Han, W. J., Lee, G. B., Kim, K. Y., Yoon, W. J., Jin, K. H., H, S., Lee, Y. H., Lee, R. K., and Lee, W. H., Ergolide, sesquiterpene lactone from Inula britannica, inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-kappaB. Br. J. Pharmacol., 133, 503-512 (2001).
7. Kasahara, Y., Hikino, H., Tsurufiji, S., Watanabe, M., and Ohuchi, K., Antiinflammatory actions of ephedrines in acute inflammations. Planta Med., 51, 325-331 (1985).
8. Kester, M., Coroneos, E., Thimas, P. J., and Dunn, M. J., Endothelin stimulates prostaglandin endoperoxide synthase-2 messenger-RNA expression and protein-synthesis through a tyrosine kinase signaling pathway in rat mesangial cells . J. Biol. Chem., 269. 22574-22580 (1994).
9. Kim, T. J., Korean floral resources , Seoul Univ. publishing company, Korea (1996).
10. Lecomte, M., Laneuville, O., Ji C., DeWitt, D. L., and Smith, W. L., Acetylation of human prostaglandin endoperoxide synthase-2 by aspirin. J. Biol. Chem., 269. 13207-13215 (1994).
11. Lee, C. B., An illustrated book of Korean plant, Hyang Mun publishing company, Korea (1973).
12. Leme, A. S., Kasahara, D. I., Nunes, M. P., Martins, M. A., and Vieira, J. E., Exhaled nitric oxide collected with two different mouthpieces: a study in asthmatic patients. Braz. J. Med. Biol. Res., 35. 1133-1137 (2002).
13. Meade, E. A., Smith, W. L., and DeWitt, D. L., Differential inhibition of prostaglandin endoperoxide synthase isozymes by aspirin and other non-steroidal antiinflammatory drugs. J. Biol. Chem., 286, 6610-6614 (1993).
14. Merlie, J. P., Fagan, D., Mudd, J., and Needleman, P., Isolation and characterization of the complementary-DNA for sheep seminal-vesicle prostaglandin endoperoxide synthase. J. Biol. Chem., 263, 3550-3551 (1988).
15. Morita, I., Schindler, M., Regier, M. K., Otto, J. C., Hori, T., DeWitt, D. L., and Smith, W. L., Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J. Biol. Chem., 270, 10902-10908 (1995).
16. Nishida, S., Kagawa, K., and Tomizawa, S., Dextran-induced paw oedema and 5-hydroxytryptamine release. Biochem. Pharmacol., 28, 3149-3150 (1979).
17. Otto, J. C. and Smith, W. L., The orientation of prostaglandin endoperoxide synthase-1 and synthase-2 in the endoplasmic reticulum. J. Biol. Chem., 269, 19868-19875 (1994).
18. Pearce, F. L., On the heterogeneity of mast cells. Pharmacology., 32, 61-71 (1986).
19. Pilbram, C. C., Kawaguchi, H., Hakeda, Y., Voznesensky, O., Alander, C. B., and Raisz, L. G., Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic Mc 3T3-E1 cells. J. Biol. Chem., 268, 25643-25649 (1993).
20. Reddy, S. T. and Herschman, H. R., Ligand induced prostaglandin synthesis requires expression of the Tis10/pgs-2 prostaglandin synthase gene in murine fibroblast and macrophages. J. Biol. Chem., 269. 15473-15480 (1994).
21. Tobacman J. K., Review of harmful gastrointestinal effects of carrageenan in animal experiments. Environ. Health Perspect, 109, 983-994 (2001).
22. Vane, J., Pharmacology-towards a better aspirin. Nature, 367, 215-216 (1994).
23. Walenga, R. W., Wall, S. F., Setty, B. N., and Stuart, M. J., Time dependent inhibition of platelet cyclo-oxygenase by indomethacin is slowly reversible. Prostaglandins, 31, 625-637 (1986).
24. Whittle B. A., The use of changes in capillary permeability in mice to distinguish between narcotic and monnarcotic analgesics. Br. J. Pharmacol., 22, 246-253 (1964).
25. Winter, C. A., Risley, E. A., and Nuss, C. W., Carrageenin-induced edema in hind paw of the rat as an assay for antiinflammatory drugs. Proc. Soc. Exp. Biol. Med., 111, 544-547 (1962).
26. Yesilada, E. and Kupeli, E., Berberis crataegina DC. root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. J. Ethnopharmacol., 79, 237-248 (2002).
27. Yesilada, E., Tanaka, S., Sezik, E., and Tabata, M., Isolation of anti-inflammatory principle from the fruit juice of Ecbalium elaterium. J. Nat. Prod., 51, 504-508 (1988).