DNA-binding affinity and nuclease activity of two cytotoxic copper terpyridine complexes

Journal of Biochemical and Molecular Toxicology

Volumn 23, Issue 4, 2009, Pages 295-302

  Shi, Pengfei ^a   Lin, Miaoxin ^b   Zhu, Jianhui ^b   Zhang, Yangmiao ^b   Jiang, Qin ^a  

^a HUAIHAI INSTITUTE OF TECHNOLOGY   (China)

^b NANJING UNIVERSITY   (China)

Author keywords

Cytotoxicity; DNA nuclease activity; DNA binding affinity; Terpyridine Cu(II)

Indexed keywords

ASCORBIC ACID; CISPLATIN; COPPER; COPPER TERPYRIDINE; DNA; DOUBLE STRANDED DNA; NUCLEASE; UNCLASSIFIED DRUG; WATER;

ARTICLE; BINDING AFFINITY; CARCINOMA CELL; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CELL STRAIN PC 3; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA CLEAVAGE; DNA DAMAGE; DRUG POTENCY; FEMALE; HUMAN; HUMAN CELL; IRRADIATION; PROSTATE CARCINOMA; STRUCTURE ACTIVITY RELATION; TITRIMETRY; ULTRAVIOLET RADIATION; UTERINE CERVIX CARCINOMA;

CELL DEATH; CELL LINE, TUMOR; COPPER; DEOXYRIBONUCLEASES; DNA; ELECTROPHORESIS, AGAR GEL; HUMANS; INHIBITORY CONCENTRATION 50; PLASMIDS; PYRIDINES; SPECTROPHOTOMETRY, ULTRAVIOLET; ULTRAVIOLET RAYS;

GALACTOPHORA;

EID: 69249086503     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.20292     Document Type: Article

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