Osteopontin gene variation and cardio/cerebrovascular disease phenotypes

Atherosclerosis

Volumn 206, Issue 1, 2009, Pages 209-215

  Schmidt Petersen, Klaus ^a   Brand, Eva ^b   Telgmann, Ralph ^a   Nicaud, Viviane ^c   Hagedorn, Claudia ^a   Labreuche, Julien ^h   Dördelmann, Corinna ^a   Elbaz, Alexis ^c   Gautier Bertrand, Marion ^c   Fischer, Jens W ^d   Evans, Alun ^e   Morrison, Caroline ^f   Arveiler, Dominique ^g   Stoll, Monika ^a   Amarenco, Pierre ^h   Cambien, François ^c   Paul, Martin ⁱ   Brand Herrmann, Stefan Martin ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c INSERM   (France)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e MONICA Project   (United Kingdom)

^f MONICA Project   (United Kingdom)

^g MONICA Project in Strasbourg   (France)

^h BICHAT HOSPITAL   (France)

ⁱ MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Brain infarction; Cardio and cerebrovascular disease; Myocardial infarction; OPN variation; Osteopontin

Indexed keywords

APOLIPOPROTEIN B; NUCLEAR PROTEIN; OSTEOPONTIN;

ADULT; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; BRAIN INFARCTION; CARDIOVASCULAR DISEASE; CAROTID ARTERY; CASE CONTROL STUDY; CELL STRAIN HEPG2; CEREBROVASCULAR DISEASE; CHROMOSOME ANALYSIS; CONTROLLED STUDY; GENE CONSTRUCT; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; HEART INFARCTION; HEART PROTECTION; HETEROZYGOTE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; NEUROPROTECTION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WESTERN BLOTTING;

AGED; BRAIN INFARCTION; CAROTID ARTERIES; CARRIER PROTEINS; CELL LINE; CELL LINE, TUMOR; CEREBROVASCULAR DISORDERS; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; OSTEOPONTIN; PHENOTYPE; POLYMORPHISM, GENETIC;

EID: 69149104433     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.02.015     Document Type: Article

References (21)

1. Oldberg A., Franzen A., and Heinegard D. Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence. Proc Natl Acad Sci USA 83 (1986) 8819-8823
2. Liaw L., Almeida M., Hart C.E., Schwartz S.M., and Giachelli C.M. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res 74 (1994) 214-224
3. Liaw L., Skinner M.P., Raines E.W., et al. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest 95 (1995) 713-724
4. Giachelli C.M., Bae N., Almeida M., et al. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques. J Clin Invest 92 (1993) 1686-1696
5. Ikeda T., Shirasawa T., Esaki Y., Yoshiki S., and Hirokawa K. Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. J Clin Invest 92 (1993) 2814-2820
6. O'Brien E.R., Garvin M.R., Stewart D.K., et al. Osteopontin is synthesized by macrophages, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arterioscler Thromb 14 (1994) 1648-1656
7. Isoda K., Nishikawa K., Kamezawa Y., et al. Osteopontin plays an important role in the development of medial thickening and neointimal formation. Circ Res 91 (2002) 77-82
8. Matsui Y., Rittling S.R., Okamoto H., et al. Osteopontin deficiency attenuates atherosclerosis in female apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 23 (2003) 1029-1034
9. Young M.F., Kerr J.M., Termine J.D., et al. cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN). Genomics 7 (1990) 491-502
10. Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16 (1988) 1215
11. Sharp D., Ricci B., Kienzle B., Lin M.C., and Wetterau J.R. Human microsomal triglyceride transfer protein large subunit gene structure. Biochemistry 33 (1994) 9057-9061
12. Tregouet D.A., Escolano S., Tiret L., Mallet A., and Golmard J.L. A new algorithm for haplotype-based association analysis: the Stochastic-EM algorithm. Ann Hum Genet 68 (2004) 165-177
13. Gómez-Ambrosi J., Catalán V., Ramírez B., et al. Plasma osteopontin levels and expression in adipose tissue are increased in obesity. J Clin Endocrinol Metab 92 (2007) 3719-3727
14. Minoretti P., Falcone C., Calcagnino M., et al. Prognostic significance of plasma osteopontin levels in patients with chronic stable angina. Eur Heart J 27 (2006) 802-807
15. Strom A., Franzen A., Wangnerud C., et al. Altered vascular remodeling in osteopontin-deficient atherosclerotic mice. J Vasc Res 41 (2004) 314-322
16. Sharp D., Blinderman L., Combs K.A., et al. Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature 365 (1993) 65-69
17. Herrmann S.M., Poirier O., Nicaud V., et al. Identification of two polymorphisms in the promoter of the microsomal triglyceride transfer protein (MTP) gene: lack of association with lipoprotein profiles. J Lipid Res 39 (1998) 2432-2435
18. Duan J., Wainwright M.S., Comeron J.M., et al. Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor. Hum Mol Genet 12 (2003) 205-216
19. Kimchi-Sarfaty C., Oh J.M., Kim I.W., et al. A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 315 (2007) 525-528
20. Brenner D., Labreuche J., Touboul P.J., et al. Cytokine polymorphisms associated with carotid intima-media thickness in stroke patients. Stroke 37 (2006) 1691-1696
21. Giacopelli F., Marciano R., Pistorio A., et al. Polymorphisms in the osteopontin promoter affect its transcriptional activity. Physiol Genomics 20 (2004) 87-96