Identification of two polymorphisms in the promoter of the microsomal triglyceride transfer protein (MTP) gene: Lack of association with lipoprotein profiles

Journal of Lipid Research

Volumn 39, Issue 12, 1998, Pages 2432-2435

  Herrmann, Stefan Martin ^a   Poirier, Odette ^a   Nicaud, Viviane ^a   Evans, Alun ^b   Ruidavets, Jean Bernard ^c   Luc, Gerard ^d   Arveiler, Dominique ^e   Bao Sheng, Chen ^f   Cambien, François ^a  

^a INSERM   (France)

^b Belfast MONICA Project   (United Kingdom)

^c MONICA Toulouse   (France)

^d MONICA Lille   (France)

^e MONICA Strasbourg   (France)

^f INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Atherosclerosis; Lipid variables; Microsomal triglyceride transfer protein; Myocardial infarction; Polymorphism

Indexed keywords

ADULT; ARTICLE; FATTY ACID TRANSPORT; GENE EXPRESSION; GENETIC POLYMORPHISM; HUMAN; LIPOPROTEIN SYNTHESIS; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0032428067     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0022-2275(20)33322-8     Document Type: Article

References (11)

1. Wetterau, J. R., K. A. Combs, S. N. Spinner, and B. J. Joiner. 1990. Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex. J. Biol. Chem. 265: 9800-9807.
2. Wetterau, J. R., and D. B. Zilversmitt. 1986. Localization of intracellular triacylglycerol and cholesteryl ester transfer activity in rat tissues. Biochim. Biophys. Acta. 875: 610-617.
3. Boren, J., M. M. Veniant, and S. G. Young. 1998. ApoB-100-containing lipoproteins are secreted by the heart. J. Clin. Invest. 101: 1197-1202.
4. Wetterau, J. R., L. P. Aggerbeck, M-E. Bouma, C. Eisenberg, A. Munck, M. Hermier, J. Schmitz, G. Gay, D. J. Rader, and R. Gregg. 1992. Absence of microsomal triglyceride transfer protein in subjects with abetalipoproteinemia. Science. 258: 999-1001.
5. Sharp, D., L. Blinderman, K. A. Combs, B. Kienzle, B. Ricci, K. Wager-Smith, C. M. Gil, C. W. Turck, M-E. Bouma, D. J. Rader, L. P. Aggerbeck, R. E. Gregg, D. A. Gordon, and J. R. Wetterau. 1993. Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinemia. Nature. 365: 65-69.
6. Shoulders, C. C., D. J. Brett, J. D. Bayliss, T. M. Narcisi, A. Jarmuz, T. T. Grantham, P. R. D. Leoni, S. Bhattachayara, R. J. Pease, P. M. Cullen, S. Levi, P. G. H. Byfield, P. Purkiss, and J. Scott. 1993. Abetalipoproteinemia is caused by defects of the gene encoding the 97 kDa subunit of a microsomal triglyceride transfer protein. Hum. Mol. Genet. 12: 2109-2116.
7. Kane, J. P., and R. J. Havel. 1989. Disorders of the biogenesis and secretion of lipoproteins containing the B apolipoproteins. In The Metabolic Basis of Inherited Disease. 6th ed. C. R. Scriver, A. L. Beaudet, W. S. Sly, and D. Valle, editors. McGraw-Hill, New York, NY. 1139-1164.
8. Parra, H. J., D. Arveiler, A. E. Evans, J. P. Cambou, P. Amouyel, A. Bingham, D. McMaster, P. Schaffer, P. Douste-Blazy, G. Luc, J. L. Richard, P. Ducimetière, and F. Cambien. 1992. A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease: the ECTIM Study. Arterioscler. Thromb. 12: 701-707.
9. WHO MONICA Project principal investigators. 1988. The World Health Organization MONICA project (MONItoring trends and determinants in CArdiovascular disease): a major international collaboration. J. Clin. Epidemiol. 41: 105-114.
10. Behague, I., O. Poirier, V. Nicaud, A. Evans, D. Arveiler, G. Luc, J-P. Cambou, P-C. Scarabin, L. Bara, F. Green, and F. Cambien. 1996. β Fibrinogen gene polymorphisms are associated with plasma fibrinogen and coronary artery disease in patients with myocardial infarction. The ECTIM Study. Circulation. 93: 440-449.
11. Orita, M., H. Iwahana, H. Kanazawa, K. Hayashi, and T. Sekiya. 1989. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphism. Proc. Natl. Acad. Sci. USA. 86: 2766-2770.