Mathematical modeling supports substantial mouse neural progenitor cell death

Neural Development

Volumn 4, Issue 1, 2009, Pages

  McConnell, Michael J ^a,b   MacMillan, Hugh R ^c   Chun, Jerold ^b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c CLEMSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ANIMAL EMBRYO; ARTICLE; BIOLOGICAL MODEL; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; COMPUTER SIMULATION; MOUSE; NERVE CELL; PHYSIOLOGY; STEM CELL;

ANIMALS; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; COMPUTER SIMULATION; EMBRYO, MAMMALIAN; MICE; MODELS, NEUROLOGICAL; NEURONS; STEM CELLS;

EID: 69149101217     PISSN: None     EISSN: 17498104     Source Type: Journal    
DOI: 10.1186/1749-8104-4-28     Document Type: Article

References (55)

1. The cell biology of neurogenesis. M Gotz WB Huttner, Nat Rev Mol Cell Biol 2005 6 777 788 10.1038/nrm1739 16314867 (Pubitemid 41726116)
2. LeX is expressed by principle progenitor cells in the embryonic nervous system, is secreted into their environment and binds Wnt-1. A Capela S Temple, Dev Biol 2006 291 300 313 10.1016/j.ydbio.2005.12.030 16458284
3. Cortical development: new concepts. G Fishell A Kriegstein, Neuron 2005 46 361 362 10.1016/j.neuron.2005.04.016 15882631 (Pubitemid 40616875)
4. Development of the human cerebral cortex: Boulder Committee revisited. I Bystron C Blakemore P Rakic, Nat Rev Neurosci 2008 9 110 122 10.1038/nrn2252 18209730
5. Autoradiographic study of cell migration during histogenesis of the cerebral cortex of the mouse. JB Angevine RL Sidman, Nature 1961 192 766 768 10.1038/192766b0 17533671
6. The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall. T Takahashi RS Nowakowski VS Caviness Jr, J Neurosci 1995 15 6046 6057 7666188
7. SA Bayar J Altman, Neocortical Development New York: Raven Press Ltd 1991
8. A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution. P Rakic, Trends Neurosci 1995 18 383 388 10.1016/0166-2236(95)93934-P 7482803
9. Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion. A Kriegstein S Noctor V Martinez-Cerdeno, Nat Rev Neurosci 2006 7 883 890 10.1038/nrn2008 17033683 (Pubitemid 44624180)
10. Early ontogeny of the secondary proliferative population of the embryonic murine cerebral wall. T Takahashi RS Nowakowski VS Caviness Jr, J Neurosci 1995 15 6058 6068 7666189
11. Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis. W Haubensak A Attardo W Denk WB Huttner, Proc Natl Acad Sci USA 2004 101 3196 3201 14963232 10.1073/pnas. 0308600100 (Pubitemid 38327757)
12. Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases. SC Noctor V Martinez-Cerdeno L Ivic AR Kriegstein, Nat Neurosci 2004 7 136 144 10.1038/nn1172 14703572 (Pubitemid 38129789)
13. Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. C Englund A Fink C Lau D Pham RA Daza A Bulfone T Kowalczyk RF Hevner, J Neurosci 2005 25 247 251 10.1523/JNEUROSCI.2899-04.2005 15634788 (Pubitemid 40110787)
14. The leaving or Q fraction of the murine cerebral proliferative epithelium: a general model of neocortical neuronogenesis. T Takahashi RS Nowakowski VS Caviness Jr, J Neurosci 1996 16 6183 6196 8815900
15. Role of founder cell deficit and delayed neuronogenesis in microencephaly of the trisomy 16 mouse. TF Haydar RS Nowakowski PJ Yarowsky BK Krueger, J Neurosci 2000 20 4156 4164 10818151
16. Fibroblast growth factor signaling regulates growth and morphogenesis at multiple steps during brain development. FM Vaccarino ML Schwartz R Raballo J Rhee R Lyn-Cook, Curr Top Dev Biol 1999 46 179 200 10.1016/S0070-2153(08)60329-4 10417880
17. The role of cell death during neocortical neurogenesis and synaptogenesis: implications from a computational model for the rat and mouse. JM Gohlke WC Griffith EM Faustman, Brain Res Dev Brain Res 2004 151 43 54 10.1016/j.devbrainres.2004.03.020 15246691 (Pubitemid 38887732)
18. Neuronogenesis and the early events of neocortical histogenesis. VS Caviness Jr T Takahashi RS Nowakowski, Results Probl Cell Differ 2000 30 107 143 10857187
19. Size distribution of retrovirally marked lineages matches prediction from population measurements of cell cycle behavior. L Cai NL Hayes T Takahashi VS Caviness Jr RS Nowakowski, J Neurosci Res 2002 69 731 744 10.1002/jnr.10398 12205666 (Pubitemid 34984690)
20. Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex. AJ Blaschke K Staley J Chun, Development 1996 122 1165 1174 8620843
21. Identification of neural programmed cell death through the detection of DNA fragmentation in situ and by PCR. YC Yung G Kennedy J Chun, Curr Protoc Neurosci 2009 Chapter 3 Unit 3.8 19575470
22. Identification of neural programmed cell death through the detection of DNA fragmentation in situ and by PCR. J Chun AJ Blaschke, Curr Protoc Neurosci 2001 Chapter 3 Unit 3.8 18428472
23. Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends. K Staley AJ Blaschke J Chun, Cell Death Differ 1997 4 66 75 10.1038/sj.cdd.4400207 16465212
24. Programmed cell death is a universal feature of embryonic and postnatal neuroproliferative regions throughout the central nervous system. AJ Blaschke JA Weiner J Chun, J Comp Neurol 1998 396 39 50 10.1002/(SICI)1096-9861(19980622) 396:1<39::AID-CNE4>3.0.CO;2-J 9623886
25. Widespread tangential dispersion and extensive cell death during early neurogenesis in the mouse neocortex. AL Wilkie SA Jordan JA Sharpe DJ Price IJ Jackson, Dev Biol 2004 267 109 118 10.1016/j.ydbio.2003.11.006 14975720 (Pubitemid 38234737)
26. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. K Kuida TS Zheng S Na C Kuan D Yang H Karasuyama P Rakic RA Flavell, Nature 1996 384 368 372 10.1038/384368a0 8934524 (Pubitemid 26408520)
27. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. K Kuida TF Haydar CY Kuan Y Gu C Taya H Karasuyama MS Su P Rakic RA Flavell, Cell 1998 94 325 337 10.1016/S0092-8674(00)81476-2 9708735 (Pubitemid 28376077)
28. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. H Yoshida YY Kong R Yoshida AJ Elia A Hakem R Hakem JM Penninger TW Mak, Cell 1998 94 739 750 10.1016/S0092-8674(00)81733-X 9753321 (Pubitemid 28436006)
29. The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool. T Lindsten JA Golden WX Zong J Minarcik MH Harris CB Thompson, J Neurosci 2003 23 11112 11119 14657169
30. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. M Groszer R Erickson DD Scripture-Adams R Lesche A Trumpp JA Zack HI Kornblum X Liu H Wu, Science 2001 294 2186 2189 10.1126/science.1065518 11691952 (Pubitemid 33150679)
31. Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. V Depaepe N Suarez-Gonzalez A Dufour L Passante JA Gorski KR Jones C Ledent P Vanderhaeghen, Nature 2005 435 1244 1250 10.1038/nature03651 15902206 (Pubitemid 40943090)
32. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. N Motoyama F Wang KA Roth H Sawa K Nakayama I Negishi S Senju Q Zhang S Fujii, Science 1995 267 1506 1510 10.1126/science.7878471 7878471
33. Essential role for survivin in early brain development. Y Jiang A de Bruin H Caldas J Fangusaro J Hayes EM Conway ML Robinson RA Altura, J Neurosci 2005 25 6962 6970 10.1523/JNEUROSCI.1446-05.2005 16049172 (Pubitemid 41077004)
34. Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage. N Arbour JL Vanderluit JN Le Grand A Jahani-Asl VA Ruzhynsky EC Cheung MA Kelly AE MacKenzie DS Park JT Opferman RS Slack, J Neurosci 2008 28 6068 6078 18550749 10.1523/JNEUROSCI.4940-07.2008
35. Apoptosis and its relation to the cell cycle in the developing cerebral cortex. D Thomaidou MC Mione JF Cavanagh JG Parnavelas, J Neurosci 1997 17 1075 1085 8994062
36. A Saltelli S Tarantola F Campolongo M Ratto, Sensitivity Analysis in Practice: a Guide to Assessing Scientific Models Hoboken, NJ: Wiley 2004
37. A gradient in the duration of the G1 phase in the murine neocortical proliferative epithelium. S Miyama T Takahashi RS Nowakowski VS Caviness Jr, Cereb Cortex 1997 7 678 689 10.1093/cercor/7.7.678 9373022 (Pubitemid 27467978)
38. Cell death in early neural development: beyond the neurotrophic theory. EJ de la Rosa F de Pablo, Trends Neurosci 2000 23 454 458 10.1016/S0166-2236(00) 01628-3 11006461 (Pubitemid 30690290)
39. In vivo cellular and molecular mechanisms of neuronal apoptosis in the mammalian CNS. L Lossi A Merighi, Prog Neurobiol 2003 69 287 312 10.1016/S0301-0082(03)00051-0 12787572 (Pubitemid 36645051)
40. Cell birth, cell death, cell diversity and DNA breaks: how do they all fit together? EC Gilmore RS Nowakowski VS Caviness Jr K Herrup, Trends Neurosci 2000 23 100 105 10.1016/S0166-2236(99)01503-9 10675909 (Pubitemid 30110622)
41. Cell death, DNA breaks and possible rearrangements: an alternative view. J Chun, Trends Neurosci 2000 23 407 409 10.1016/S0166-2236(00)01612-X 10941186 (Pubitemid 30674170)
42. Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system. M Pompeiano AJ Blaschke RA Flavell A Srinivasan J Chun, J Comp Neurol 2000 423 1 12 10.1002/1096- 9861(20000717)423:1<1::AID-CNE1>3.0.CO;2-S 10861532
43. Onset of apoptotic DNA fragmentation can precede cell elimination by days in the small intestinal villus. M Pompeiano M Hvala J Chun, Cell Death Differ 1998 5 702 709 10.1038/sj.cdd.4400403 10200526
44. A computational model for neocortical neuronogenesis predicts ethanol-induced neocortical neuron number deficits. JM Gohlke WC Griffith SM Bartell TA Lewandowski EM Faustman, Dev Neurosci 2002 24 467 477 10.1159/000069357 12697984 (Pubitemid 36438781)
45. Computational models of neocortical neuronogenesis and programmed cell death in the developing mouse, monkey, and human. JM Gohlke WC Griffith EM Faustman, Cereb Cortex 2007 17 2433 2442 10.1093/cercor/bhl151 17204816 (Pubitemid 47517478)
46. The role of cell death in regulating the size and shape of the mammalian forebrain. TF Haydar CY Kuan RA Flavell P Rakic, Cereb Cortex 1999 9 621 626 10.1093/cercor/9.6.621 10498280 (Pubitemid 29441503)
47. Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotpic instability. C Mantel Y Guo MR Lee MK Kim MK Han H Shibayama S Fukuda MC Yoder LM Pelus KS Kim HE Broxmeyer, Blood 2007 109 4518 4527 17289813 10.1182/blood-2006-10-054247 (Pubitemid 46743423)
48. Decatenation checkpoint deficiency in stem and progenitor cells. M Damelin YE Sun VB Sodja TH Bestor, Cancer Cell 2005 8 479 484 10.1016/j.ccr.2005.11.004 16338661 (Pubitemid 41773451)
49. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Q Shen SK Goderie L Jin N Karanth Y Sun N Abramova P Vincent K Pumiglia S Temple, Science 2004 304 1338 1340 10.1126/science.1095505 15060285 (Pubitemid 38697433)
50. Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system. JW Jiao DA Feldheim DF Chen, Proc Natl Acad Sci USA 2008 105 8778 8783 18562299 10.1073/pnas.0708861105 (Pubitemid 351987756)
51. Chromosomal variation in neurons of the developing and adult mammalian nervous system. SK Rehen MJ McConnell D Kaushal MA Kingsbury AH Yang J Chun, Proc Natl Acad Sci USA 2001 98 13361 13366 11698687 10.1073/pnas.231487398 (Pubitemid 33051368)
52. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. AR Muotri VT Chu MC Marchetto W Deng JV Moran FH Gage, Nature 2005 435 903 910 10.1038/nature03663 15959507 (Pubitemid 40896309)
53. Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy. I Cobos ME Calcagnotto AJ Vilaythong MT Thwin JL Noebels SC Baraban JL Rubenstein, Nat Neurosci 2005 8 1059 1068 10.1038/nn1499 16007083 (Pubitemid 41061517)
54. Altered interneuron development in the cerebral cortex of the flathead mutant. MR Sarkisian M Frenkel W Li JA Oborski JJ LoTurco, Cereb Cortex 2001 11 734 743 10.1093/cercor/11.8.734 11459763
55. Independent controls for neocortical neuron production and histogenetic cell death. C Verney T Takahashi PG Bhide RS Nowakowski VS Caviness Jr, Dev Neurosci 2000 22 125 138 10.1159/000017434 10657705