Is there a place for quantitative risk assessment?

Journal of Radiological Protection

Volumn 29, Issue 2, 2009, Pages

  Hall, Eric J ^a  

^a Howard Hughes Medical Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY DOSE; CRITICAL QUESTIONS; CT SCAN; DIAGNOSTIC PROCEDURE; DOSE DISTRIBUTIONS; DOSE RESPONSE; HIGH DOSE; HUMAN CARCINOGEN; INTERVENTIONAL RADIOLOGY; IONISING RADIATION; KNOW-HOW; LOW DOSE; LOWER LIMITS; LUMBAR SPINES; MONITOR UNITS; NEUTRON DOSE; NONUNIFORM; NUCLEAR POWER; PENCIL BEAM; POTENTIAL HAZARDS; PRACTICAL PROBLEMS; QUANTITATIVE RISK; QUANTITATIVE RISK ASSESSMENT; RADIATION FIELD; RADIATION ONCOLOGY; RADIATION RISK; RELATIVE BIOLOGICAL EFFECTIVENESS; SINGLE-DOSE; SPOT SCANNING; TARGET VOLUMES; TECHNICAL PROBLEM;

BARIUM; COMPUTERIZED TOMOGRAPHY; COST REDUCTION; IONIZING RADIATION; NEUTRONS; ONCOLOGY; PHYSICAL THERAPY; PROTONS; RADIATION HAZARDS; RADIOACTIVITY; RADIOTHERAPY; RISK MANAGEMENT; UNCERTAINTY ANALYSIS;

RISK ASSESSMENT;

PROTON;

COMPUTER ASSISTED TOMOGRAPHY; HUMAN; INTENSITY MODULATED RADIATION THERAPY; ONCOLOGY; RADIATION INJURY; RADIATION RESPONSE; REVIEW; RISK ASSESSMENT;

DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; NEOPLASMS, RADIATION-INDUCED; PROTONS; RADIATION ONCOLOGY; RADIOTHERAPY, INTENSITY-MODULATED; RISK ASSESSMENT; TOMOGRAPHY, X-RAY COMPUTED;

EID: 69149087404     PISSN: 09524746     EISSN: 13616498     Source Type: Journal    
DOI: 10.1088/0952-4746/29/2A/S12     Document Type: Review

References (38)

1. Berrington A, Darby S C, Weiss H A and Doll R 2001 100 years of observation on British radiologists: mortality from cancer and other causes 1897-1997 Br. J. Radiol. 74 507-19
2. Carpenter L M, Swerdlow A J and Fear N T 1997 Mortality of doctors in different specialties: finding from a cohort of 20 000 NHS hospital consultants Occup. Environ. Med. 54 388-95
3. ICRP 1958 Report on 1956 amendments to the recommends of the International Commission on Radiological Protection (ICRP) Radiology 70 261-2
4. NAS/NRC (National Academy of Sciences/National Research Council) 1956 The Biological Effects of Atomic Radiation (BEAR) Report, NAS/NRC Washington, DC
5. (MRC) Medical Research Council 1956 The hazards to man of nuclear and allied radiations Cmd 9780 HMS Office, London
6. ICRP 1959 Recommendations of the International Commission of Radiological Protection (adopted September 9, 1958) ICRP Publication 1 (Oxford: Pergamon)
7. Sankaranarayannan K and Wassom J S 2008 Reflections on the impact of advances in the assessment of genetic risks of exposure to ionizing radiation on international radiation protection recommendations between the mid-1950s and the present Mutat. Res. 658 1-27
8. -2005 Health Risks from Exposure to Low Levels of Ionizing Radiation-BEIR VII (Washington, DC: National Academies Press)
9. Preston D L et al 2004 Effect of recent changes in atomic bomb survivor dosimetry on cancer mortality risk estimates Radiat. Res. 162 377-89
10. Preston D L, Shimizu Y, Pierce D A, Suyama A and Mabuchi K 2003 Studies of mortality of atomic bomb survivors. Report 13: solid cancer and noncancer disease mortality: 1950-1997 Radiat. Res. 160 381-407
11. Pierce D A and Preston D L 2000 Radiation-related cancer risks at low doses among atomic bomb survivors Radiat. Res. 154 178-86
12. Preston D L et al 2007 Solid cancer incidence in atomic bomb survivors: 1958-1998 Radiat. Res. 168 1-64
13. Hall E J 2004 The crooked shall be made straight; dose-response relationships for carcinogenesis. Henry S Kaplan Distinguished Scientist Award 2003 Int. J. Radiat. Biol. Oncol. Phys. 80 327-37
14. Brenner D J et al 2000 Second malignancies in prostate patients after radiotherapy compared with surgery Cancer 88 398-406
15. Hall E J 2006 Intensity-modulated radiation therapy, protons, and the risk of second cancers Int. J. Radiat. Biol. Phys. 65 1-7
16. Sachs R K and Brenner D J 2005 Solid tumor risks after high doses of ionizing radiation Proc. Natl Acad. Sci. USA 102 13040-5
17. Hall E J and Wuu C 2003 Radiation-induced second cancers: the impact of 3D-CRT and IMRT Int. J. Radiat. Oncol. Biol. Phys. 56 83-8
18. Kry S F et al 2005 The calculated risk of fatal secondary malignancies from intensity-modulated radiation therapy Int. J. Radiat. Oncol. Biol. Phys. 62 1195-203
19. Kellerer A M, Ruhm W and Walsh L 2006 Indications of the neutron effect contribution in the solid cancer data of the A-bomb survivors Health Phys. 90 554-64
20. Ullrich R L 1983 Tumor induction in BALB/c female mice after fission neutron or gamma irradiation Radiat. Res. 93 506-15
21. Ullrich R L 1984 Tumor induction in BALB/c mice after fractionated or protracted exposures to fission-spectrum neutrons Radiat. Res. 97 587-97
22. Lloyd D C, Purrott R J, Dolphin G W and Edwards A A 1976 Chromosome aberrations induced in human lympohcytes by neutron irradiation Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 29 169-82
23. Yan X et al 2002 Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field Nucl. Instrum. Methods Phys. Res. A 476 429-34
24. Zheng Y, Newhauser W, Fontenot J, Taddei P and Mohan R 2007 Monte Carlo study of neutron dose equivalent during passive scattering proton therapy Phys. Med. Biol. 52 4481-96
25. Wroe A, Rosenfeld A and Schulte R 1007 Out-of-field dose equivalents delivered by proton therapy of prostate cancer Med. Phys. 34 3449-56
26. Schneider U et al 2002 Secondary neutron dose during proton therapy using spot scanning Int. J. Radiat. Oncol. Biol. Phys. 53 244-51
27. Mesoloras G, Sandison G A, Stewart R D, Farr J B and Hsi W C 2006 Neutron scattered dose equivalent to a fetus from proton radiotherapy to the mother Med. Phys. 33 2479-90
28. Brenner D J and Hall E J 2008 Secondary neutrons in clinical proton radiotherapy: a charged issue Radiother. Oncol. 86 165-70
29. Jiang H, Wang B, Xu X G, Suit H D and Paganetti H 2005 Simulation of organ-specific patient effective dose due to secondary neutrons in proton radiation treatment Phys. Med. Biol. 50 4337-53
30. Brenner D J et al 2003 Cancer risks attributable to low doses of ionizing radiation: assessing what we really know Proc. Natl Acad. Sci. USA 100 13761-6
31. Cardis E et al 2007 The 15-country collaborative study of cancer risk among radiation workers in the nuclear industry: estimates of radiation-related cancer risks Radiat. Res. 167 396-416 (Pubitemid 351292972)
32. Mettler F A Jr, Thomadsen B R, Bhargavan M, Gilley D B, Gray J E, Lipoti J A, McCrohan J, Yoshizumi T T and Mahesh M 2008 Medical radiation exposure in the U.S. in 2006: preliminary results Health Phys. 95 502-7
33. Hall E J and Brenner D J 2008 Cancer risks from diagnostic radiology Br. J. Radiol. 81 362-78
34. Brenner D J and Hall E J 2007 Computed tomography-an increasing source of radiation exposure N. Engl. J. Med. 357 2277-84
35. UK Department of Health Department of Health Hospital Activity Statistics: Imaging and Radiodiagnostics Data files Available from: http://www.performance.doh.gov.uk/hospitalactivity/data-requests/ imaging-and-radiodiagnostics.htm (Accessed 12 February 2008)
36. International Marketing Ventures 2006 CT Market Summary Report (Rockville, MD) Available from: http://www.imvinfo.com (Accessed 12 February 2008)
37. The Royal Society of London 1983 Risk Assessment: A Study Group Report (London: Royal Society of London)
38. COMARE (Committee on Medical Aspects of Radiation in The Environment) 2007 Twelfth Report 'The Impact of Personally Initiated X-Ray Computed Tomography Scanning for the Health Assessment of Asymptomatic Individuals (Didcot: Health Protection Agency) Available from: http//www.comare.org.uk/ documents/COMARE12thReport.pdf (Accessed 12 February 2008)