Interleukin-1β-induced extracellular matrix degradation and glycosaminoglycan release is inhibited by curcumin in an explant model of cartilage inflammation

Annals of the New York Academy of Sciences

Volumn 1171, Issue , 2009, Pages 428-435

  Clutterbuck, Abigail L ^a   Mobasheri, Ali ^a   Shakibaei, Mehdi ^b   Allaway, David ^c   Harris, Pat ^c  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF MUNICH   (Germany)

^c WALTHAM CENTRE FOR PET NUTRITION   (United Kingdom)

Author keywords

Cartilage; Curcumin; Cytokine; Equine; Glycosaminoglycan; Inflammation; Osteoarthritis; Polyphenol

Indexed keywords

CURCUMIN; CYTOKINE; GLYCOSAMINOGLYCAN; INTERLEUKIN 1BETA; METHYLENE BLUE; NONSTEROID ANTIINFLAMMATORY AGENT; SOMATOMEDIN C;

ANIMAL TISSUE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE RELEASE; DEGRADATION; EXPLANT; EXTRACELLULAR MATRIX; GENE EXPRESSION; HORSE; INFLAMMATION; METACARPOPHALANGEAL JOINT; METATARSOPHALANGEAL JOINT; NONHUMAN; OSTEOARTHRITIS; PROTEIN SECRETION; ANIMAL; ARTICLE; CARTILAGE; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PATHOLOGY; SECRETION; TISSUE CULTURE TECHNIQUE;

CURCUMA LONGA; EQUIDAE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARTILAGE; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR MATRIX; GLYCOSAMINOGLYCANS; HORSES; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-1BETA; METACARPOPHALANGEAL JOINT; OSTEOARTHRITIS; TISSUE CULTURE TECHNIQUES;

EID: 69149083384     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.04687.x     Document Type: Conference Paper

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