Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus

Development

Volumn 136, Issue 15, 2009, Pages 2535-2543

  Huang, Xi ^a   Ketova, Tatiana ^a   Fleming, Jonathan T ^a   Wang, Haibin ^b   Dey, Sudhansu K ^c   Litingtung, Ying ^a   Chiang, Chin ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTE OF ZOOLOGY   (China)

^c CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

Author keywords

Cerebrospinal fluid; Choroid plexus; Epithelium; Gli1; Shh

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOGENESIS; BLOOD CEREBROSPINAL FLUID BARRIER; CELL PROLIFERATION; CEREBROSPINAL FLUID; CHOROID PLEXUS; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE CONTROL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CHOROID PLEXUS; EPITHELIAL CELLS; GENE DELETION; GROWTH DIFFERENTIATION FACTORS; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; INTEGRASES; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MODELS, BIOLOGICAL; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; STEM CELLS; WNT PROTEINS;

ERINACEIDAE;

EID: 69049118160     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.033795     Document Type: Article

References (34)

1. Ahn, S. and Joyner, A. L. (2004). Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning. Cell 118, 505-516.
2. Awatramani, R., Soriano, P., Rodriguez, C., Mai, J. J. and Dymecki, S. M. (2003). Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat. Genet. 35, 70-75.
3. Bill, B. R., Balciunas, D., McCarra, J. A., Young, E. D., Xiong, T., Spahn, A. M., Garcia-Lecea, M., Korzh, V., Ekker, S. C. and Schimmenti, L. A. (2008). Development and Notch signaling requirements of the zebrafish choroid plexus. PLoS ONE 3, e3114.
4. Bitgood, M. J. and McMahon, A. P. (1995). Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol. 172, 126-138.
5. Cheng, X., Hsu, C. M., Currle, D. S., Hu, J. S., Barkovich, A. J. and Monuki, E. S. (2006). Central roles of the roof plate in telencephalic development and holoprosencephaly. J. Neurosci. 26, 7640-7649.
6. Chizhikov, V. V., Lindgren, A. G., Currle, D. S., Rose, M. F., Monuki, E. S. and Millen, K. J. (2006). The roof plate regulates cerebellar cell-type specification and proliferation. Development 133, 2793-2804.
7. Currle, D. S., Cheng, X., Hsu, C. M. and Monuki, E. S. (2005). Direct and indirect roles of CNS dorsal midline cells in choroid plexus epithelia formation. Development 132, 3549-3559.
8. Dahmane, N. and Ruiz i Altaba, A. (1999). Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 126, 3089-3100.
9. Dang, L., Fan, X., Chaudhry, A., Wang, M., Gaiano, N. and Eberhart, C. G. (2006). Notch3 signaling initiates choroid plexus tumor formation. Oncogene 25, 487-491.
10. Emerich, D. F., Skinner, S. J., Borlongan, C. V., Vasconcellos, A. V. and Thanos, C. G. (2005). The choroid plexus in the rise, fall and repair of the brain. BioEssays 27, 262-274.
11. Garcia-Lecea, M., Kondrychyn, I., Fong, S. H., Ye, Z. R. and Korzh, V. (2008). In vivo analysis of choroid plexus morphogenesis in zebrafish. PLoS ONE 3, e3090.
12. Goodrich, L. V., Johnson, R. L., Milenkovic, L., McMahon, J. A. and Scott, M. P. (1996). Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 10, 301-312.
13. Goodrich, L. V., Milenkovic, L., Higgins, K. M. and Scott, M. P. (1997). Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277, 1109-1113.
14. Gopal, P., Parker, J. R., Debski, R. and Parker, J. C., Jr (2008). Choroid plexus carcinoma. Arch. Pathol. Lab. Med. 132, 1350-1354.
15. Hebert, J. M., Mishina, Y. and McConnell, S. K. (2002). BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron 35, 1029-1041.
16. Huang, X., Litingtung, Y. and Chiang, C. (2007). Ectopic sonic hedgehog signaling impairs telencephalic dorsal midline development: implication for human holoprosencephaly. Hum. Mol. Genet. 16, 1454-1468.
17. Hunter, N. L. and Dymecki, S. M. (2007). Molecularly and temporally separable lineages form the hindbrain roof plate and contribute differentially to the choroid plexus. Development 134, 3449-3460.
18. Ingham, P. W. and McMahon, A. P. (2001). Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 15, 3059-3087.
19. Jeong, J., Mao, J., Tenzen, T., Kottmann, A. H. and McMahon, A. P. (2004). Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia. Genes Dev. 18, 937-951.
20. Jiang, X., Rowitch, D. H., Soriano, P., McMahon, A. P. and Sucov, H. M. (2000). Fate of the mammalian cardiac neural crest. Development 127, 1607-1616.
21. Komada, M., Saitsu, H., Kinboshi, M., Miura, T., Shiota, K. and Ishibashi, M. (2008). Hedgehog signaling is involved in development of the neocortex. Development 135, 2717-2727.
22. Lee, K. J., Dietrich, P. and Jessell, T. M. (2000). Genetic ablation reveals that the roof plate is essential for dorsal interneuron specification. Nature 403, 734-740.
23. Lewis, P. M., Dunn, M. P., McMahon, J. A., Logan, M., Martin, J. F., St-Jacques, B. and McMahon, A. P. (2001). Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell 105, 599-612.
24. Minowada, G., Jarvis, L. A., Chi, C. L., Neubuser, A., Sun, X., Hacohen, N., Krasnow, M. A. and Martin, G. R. (1999). Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126, 4465-4475.
25. Motoyama, J., Takabatake, T., Takeshima, K. and Hui, C. (1998). Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog. Nat. Genet. 18, 104-106.
26. Redzic, Z. B., Preston, J. E., Duncan, J. A., Chodobski, A. and Szmydynger-Chodobska, J. (2005). The choroid plexus-cerebrospinal fluid system: from development to aging. Curr. Top. Dev. Biol. 71, 1-52.
27. Segal, M. B. (2000). The choroid plexuses and the barriers between the blood and the cerebrospinal fluid. Cell. Mol. Neurobiol. 20, 183-196.
28. Soriano, P. (1999). Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71.
29. Srinivas, S., Watanabe, T., Lin, C. S., William, C. M., Tanabe, Y., Jessell, T. M. and Costantini, F. (2001). Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 1, 4.
30. Sturrock, R. R. (1979). A morphological study of the development of the mouse choroid plexus. J. Anat. 129, 777-793.
31. Tannahill, D., Harris, L. W. and Keynes, R. (2005). Role of morphogens in brain growth. J. Neurobiol. 64, 367-375.
32. Thomas, T. and Dziadek, M. (1993). Capacity to form choroid plexus-like cells in vitro is restricted to specific regions of the mouse neural ectoderm. Development 117, 253-262.
33. Wallace, V. A. (1999). Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum. Curr. Biol. 9, 445-448.
34. Wechsler-Reya, R. J. and Scott, M. P. (1999). Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog. Neuron 22, 103-114.