A peroxisome proliferator-activated receptor-gamma agonist and other constituents from Chromolaena odorata

Planta Medica

Volumn 75, Issue 8, 2009, Pages 803-807

  Nguyen, Tien Dat ^a,b,c   Lee, Kyeong ^a   Hong, Young Soo ^a   Young, Ho Kim ^b   Chau, Van Minh ^c   Jung, Joon Lee ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

^c GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Viet Nam)

Author keywords

(9S,13R) 12 oxo phytodienoic acid; Asteraceae; Chromolaena odorata; Chromomoric acid G; PPAR

Indexed keywords

12 OXO PHYTODIENOIC ACID; 15,16 DIDEHYDROCORIOLIC ACID; 2,4 DIHYDROXY, 3',4',7 TRIMETHOXYFLAVONE; 4',5,6,7' TETRAMETHOXYFLAVONE; 4,6' DIHYDROXY 2',3',4' TRIMETHOXYCHALCONE; ACACETIN; CHROMOLAENA ODORATA EXTRACT; CHROMOLANONE; CHROMOMORIC ACID G; CORIOLIC ACID; FATTY ACID DERIVATIVE; FLAVONOID; ISOKAEMPFERIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PLANT EXTRACT; ROSIGLITAZONE; SALVIGENIN; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHROMOLAENA; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVATION; GLUCOSE METABOLISM; LIPID METABOLISM; NONHUMAN;

CHROMOLAENA; FATTY ACIDS, UNSATURATED; FLAVONOIDS; HUMANS; HYPOGLYCEMIC AGENTS; PLANT EXTRACTS; PPAR GAMMA; PROSTAGLANDINS; THIAZOLIDINEDIONES;

ASTERACEAE; CHROMOLAENA ODORATA;

EID: 69049117262     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1185386     Document Type: Article

References (29)

1. Thang PT, See P, Lee ST, Chan SY. Anti-oxidant effects of the extracts from the leaves of Chromolaena odorata on human dermal fibroblasts and epidermal keratinocytes against hydrogen peroxide and hypoxanthine-xanthine oxidase induced damage. Burns 2001; 27: 319-327
2. Bamba D, Bessiere JM, Marion C, Pelissier Y, Fourate I. Essential oil of Eupatorium odoratum. Planta Med 1993; 59: 184-185
3. Irobi ON. Activities of Chromolaena odorata (Compositae) leaf extract against Pseudomonas aeruginosa and Streptococcus faecalis. J Ethnopharmacol 1992; 37: 81-83
4. Caceres A, Menéndez H, Mendez E, Cohobon E, Samayoa BE, Jauregui E, Peralta E, Carrillo G. Antigonorrhoeal activity of plants used in Guatemala for the treatment of sexually transmitted diseases. J Ethnopharmacol 1995; 48: 85-88
5. Wollenweber E, Dörr M, Muniappan R. Exudate flavonoids in a tropical weed, Chromolaena odorata (L.) R. M. King et H. Robinson. Biochem Syst Ecol 1995; 23: 873-874
6. Barua RN, Sharma RP, Thyagarajan G, Hertz W. Flavonoids of Chromolaena odorata. Phytochemistry 1978; 17: 1807-1808
7. Biller A, Boppre M, Witte L, Hartmann T. Pyrrolizidine alkaloids in Chromolaena odorata. Chemical and chemoecological aspects. Phytochemistry 1994; 35: 615-619
8. Sunil K, Durga T, Bhar S, Talapatra B. Flavonoid and terpenoid constituents of Eupatorium odoratum. Phytochemistry 1974; 13: 284-285
9. Schoonjans K, Staels B, Auwerx J. The peroxisome proliferator-activated receptor (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochim Biophys Acta 1996; 1302: 93-109 (Pubitemid 26247079)
10. Rangwala SM, Lazar MA. Peroxisome proliferator-activated receptor γ in diabetes and metabolism. Trends Pharm Sci 2004; 25: 331-336 (Pubitemid 38692426)
11. Murphy GJ, Holder JC. PPAR-γ agonists: therapeutic role in diabetes, inflammation and cancer. Trends Pharm Sci 2000; 21: 469-474
12. Hwang BY, Lee JH, Nam JB, Kim HS, Hong YS, Lee JJ. Two new furanoditerpenes from Saururus chinensis and their effects on the activation of peroxisome proliferator-activated receptor γ. J Nat Prod 2002; 65: 616-617
13. Bohlmann F, Borthakur N, King RM, Robinson H. Further prostaglandinlike fatty acids from Chromolaena morii. Phytochemistry 1982; 21: 125-127
14. Bohlmann F, Singh P, Jakupovic J, King RM, Robinson H. Three cadinene derivatives and a prostaglandin-like acid from Chromolaena species. Phytochemistry 1982; 21: 371-374
15. Baertschi SW, Ingram CD, Harris TM, Brash AR. Absolute configuration of cis-12-oxophytodienoic acid of flaxseed: implications for the mechanism of biosynthesis from the 13(S)-hydroperoxide of linoleic acid. Biochemistry 1988; 27: 18-24
16. Ainai T, Matsuumi M, Kobayashi Y. Efficient total synthesis of 12-oxo-PDA and OPC-8: 0. J Org Chem 2003; 68: 7825-7832 (Pubitemid 37186138)
17. Braca A, Bilia AR, Mendez J, Morelli I. Three flavonoids from Licania densiflora. Phytochemistry 1999; 51: 1125-1128
18. Agrawal PK. Carbon-13 NMR of flavonoids. Amsterdam: Elsevier; 1989: 96-157
19. Achenbach H, Hemrich H. Alkaloids, flavonoids and phenylpropanoids of the West African plant Oxymitra velutina. Phytochemistry 1991; 30: 1265-1267
20. Bilia AR, Palme E, Marsili A, Pistelli L, Morelli I. A flavonol glycoside from Agrimonia eupatoria. Phytochemistry 1993; 32: 1078-1079
21. Dong H, Gou YL, Cao SG, Chen SX, Sim KY, Goh SH, Kini RM. Eisoenones and methylated flavonols from Amomon koenigii. Phytochemistry 1999; 50: 899-902 (Pubitemid 29135057)
22. Barua RN, Sharma RP, Thyagarajan G, Hertz W. Flavonoids of Chromolaena odorata. Phytochemistry 1978; 17: 1807-1808
23. Rathore A, Sharma SC, Tandon JS. Flavanones from Polygonum nepalense. Phytochemistry 1986; 25: 2223-2225
24. Kuklev DV, Christie WW, Durand T, Rossi JC, Vidal JP, Kasyanov SP, Akulin VN, Bezuglov VV. Synthesis of keto- and hydroxydienoic compounds from linoleic acid. Chem Phys Lipids 1997; 85: 125-134 (Pubitemid 27129790)
25. Yadav JS, Deshpande PK, Sharma GVM. Stereoselective synthesis of (S)-13-hydroxy octadeca-(9Z,11E)-di- and (9Z,11E,15Z)-trienoic acids: self-defensive substances against rice blast disease. Tetrahedron 1992; 48: 4465-4474
26. Cuzzocrea S, Pisano B, Dugo L, Ianaro A, Patel NSA, Di Paola R, Genovese T, Chatterjee PK, Fulia F, Cuzzocrea E, Di Rosa M, Caputi AP, Thiemermann C. Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-γ, reduces the development of nonseptic shock induced by zymosan in mice. Crit Care Med 2004; 32: 457-466 (Pubitemid 38234126)
27. 2 is a ligand for the adipocyte determination factor PPAR-γ. Cell 1995; 83: 803-812
28. Sznaidman ML, Haffner CD, Maloney PR, Fivush A, Chao E, Goreham D, Sierra ML, LeGrumelec C, Xu HE, Montana VG, Lambert MH, Willson TM, Oliver Jr WR, Sternbach DD. Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ): synthesis and biological activity. Bioorg Med Chem Lett 2003; 13: 1517-1521
29. Negishi M, Katoh H. Cyclopentenone prostaglandin receptors. Prostaglandins Other Lipid Mediat 2002; 68: 611-617