Lycopene inhibits PDGF-BB-induced retinal pigment epithelial cell migration by suppression of PI3K/Akt and MAPK pathways

Biochemical and Biophysical Research Communications

Volumn 388, Issue 1, 2009, Pages 172-176

  Chan, Chi Ming ^a,b   Fang, Jia You ^c   Lin, Hsin Huang ^a   Yang, Chi Yea ^d   Hung, Chi Feng ^a  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b CARDINAL TIEN HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

^d VANUNG UNIVERSITY   (Taiwan)

Author keywords

ARPE19; Cell adhesion; Cell migration; Cytotoxicity; Lycopene; MAPK; PDGF; PI3K Akt; Proliferative vitreoretinopathy; Retinal pigment epithelial cell

Indexed keywords

LYCOPENE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL VIABILITY; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIOXIDANTS; CAROTENOIDS; CELL LINE; CELL MOVEMENT; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; RETINAL PIGMENT EPITHELIUM;

EID: 69049096930     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.07.155     Document Type: Article

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