Vulnerability to (+)-methamphetamine effects and the relationship to drug disposition in pregnant rats during chronic infusion

Toxicological Sciences

Volumn 111, Issue 1, 2009, Pages 27-36

  White, Sarah J ^a   Laurenzana, Elizabeth M ^a   Gentry, William Brooks ^a   Hendrickson, Howard P ^b   Williams, David Keith ^a   Ward, Keith W ^c   Owens, Samuel Michael ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c BAUSCH AND LOMB   (United States)

Author keywords

Drug abuse; Methamphetamine; Pharmacokinetics; Pregnancy; Rat

Indexed keywords

METHAMPHETAMINE; SODIUM CHLORIDE;

ANEMIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHROMODACRYORRHEA; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISPOSITION; DRUG TOLERANCE; ENVIRONMENTAL EXPOSURE; FEMALE; GESTATION PERIOD; GNAWING; HEMATOCRIT; IMMUNOSUPPRESSIVE TREATMENT; LACRIMATION DISORDER; LETHARGY; LOCOMOTION; LONG TERM EXPOSURE; NONHUMAN; PLASMA CLEARANCE; PREGNANCY; RAT; SPRAGUE DAWLEY RAT; STEREOTYPY; SURVIVAL RATE; TOXICOKINETICS; WEIGHT REDUCTION;

ANIMALS; BLOOD PROTEINS; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; DEXTROAMPHETAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETAL DEVELOPMENT; FETUS; GESTATIONAL AGE; INFUSIONS, INTRAVENOUS; METHAMPHETAMINE; MOTOR ACTIVITY; PREGNANCY; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; STEREOTYPED BEHAVIOR;

RATTUS;

EID: 69049096123     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp127     Document Type: Article

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