Alterations in drug disposition during pregnancy: Implications for drug therapy

Expert Opinion on Drug Metabolism and Toxicology

Volumn 3, Issue 4, 2007, Pages 557-571

  Hodge, Lucy S ^a   Tracy, Timothy S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Cytochrome P450; Drug metabolism; Glucuronidation; Pharmacokinetics; Pregnancy; Transporters

Indexed keywords

ACYLTRANSFERASE; ACYLTRANSFERASE 2; ANTIRETROVIRUS AGENT; CAFFEINE; CYTOCHROME P450 1A2; CYTOCHROME P450 2A6; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A4; GLUCURONOSYLTRANSFERASE 2B7; GLYCOPROTEIN P; ISONIAZID; LAMOTRIGINE; MEPHENYTOIN; METOPROLOL; MULTIDRUG RESISTANCE PROTEIN; NICOTINE; NIFEDIPINE; OMEPRAZOLE; ORAL CONTRACEPTIVE AGENT; PARACETAMOL; PAROXETINE; PHENYTOIN; PROGUANIL; SEROTONIN UPTAKE INHIBITOR; THEOPHYLLINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; CARRIER PROTEIN; DRUG;

AREA UNDER THE CURVE; DEPRESSION; DRUG ACTIVITY; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG HALF LIFE; DRUG METABOLISM; ENZYME ACTIVITY; EPILEPSY; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION; INTRAUTERINE GROWTH RETARDATION; MALARIA; NONHUMAN; PREECLAMPSIA; PREGNANCY; PROTEIN FUNCTION; REVIEW; SEIZURE; UNSPECIFIED SIDE EFFECT; ADULT; ANIMAL; DRUG THERAPY; FEMALE; FETUS; METABOLISM; PHARMACOKINETICS; PHYSIOLOGY; PLACENTA;

ADULT; ANIMALS; CARRIER PROTEINS; DRUG THERAPY; FEMALE; FETUS; HUMANS; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; PLACENTA; PREGNANCY;

EID: 85047683695     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.3.4.557     Document Type: Review

References (143)