Using normalized EMG to define the nociceptive flexion reflex (NFR) threshold: Further evaluation of standardized NFR scoring criteria

Pain

Volumn 145, Issue 1-2, 2009, Pages 211-218

  France, Christopher R ^a   Rhudy, Jamie L ^b   McGlone, Sarah ^a  

^a OHIO UNIVERSITY   (United States)

^b UNIVERSITY OF TULSA   (United States)

Author keywords

Measurement; Nociceptive flexion reflex; Receiver operating characteristics; RIII; Threshold

Indexed keywords

ADULT; ARTICLE; ELECTROMYOGRAM; FEMALE; FLEXOR REFLEX; HUMAN; HUMAN EXPERIMENT; MALE; MEASUREMENT; MUSCLE CONTRACTION; NORMAL HUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM;

ADOLESCENT; AUTOMATIC DATA PROCESSING; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FEMALE; HUMANS; MALE; PAIN MEASUREMENT; PAIN THRESHOLD; REFLEX; ROC CURVE; YOUNG ADULT;

EID: 69049083330     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2009.06.022     Document Type: Article

References (34)

1. Andersen O.K., Graven-Nielsen T., Matre D., Arendt-Nielsen L., and Schomburg E.D. Interaction between cutaneous and muscle afferent activity in polysynaptic reflex pathways: a human experimental study. Pain 84 (2000) 29-36
2. Banic B., Petersen-Felix S., Andersen O.K., Radanov B.P., Villiger P.M., Arendt-Nielsen L., and Curatolo M. Evidence for spinal cord hypersensitivity in chronic pain after whiplash injury and in fibromyalgia. Pain 107 (2004) 7-15
3. Boureau F., Luu M., and Doubrere J.F. Study of experimental pain measures and nociceptive reflex in chronic pain patients and normal subjects. Pain 44 (1991) 131-138
4. Bromm B., and Scharein E. Principal component analysis of pain-related cerebral potentials to mechanical and electrical stimulation in man. Electroencephalogr Clin Neurophysiol 53 (1982) 94-103
5. Bromm B., and Treede R.D. Laser-evoked cerebral potentials in the assessment of cutaneous pain sensitivity in normal subjects and patients. Rev Neurol 147 (1991) 625-643
6. Chan C.W., and Dallaire M. Subjective pain sensation is linearly correlated with the flexion reflex in man. Brain Res 479 (1989) 145-150
7. Davis K.D., Wood M.L., Crawley A.P., and Mikulis D.J. FMRI of human somatosensory and cingulate cortex during painful electrical nerve stimulation. Neuroreport: Int J Rapid Commun Res Neurosci 7 (1995) 321-325
8. Desmeules J.A., Cedraschi C., Rapiti E., Baumgartner E., Finckh A., Cohen P., Dayer P., and Vischer T.L. Neurophysiologic evidence for a central sensitization in patients with fibromyalgia. Arthritis Rheum 48 (2003) 1420-1429
9. Dowman R. Spinal and supraspinal correlates of nociception in man. Pain 45 (1991) 269-281
10. Dowman R. Possible startle response contamination of the spinal nociceptive withdrawal reflex. Pain 49 (1992) 187-197
11. Edwards L., McIntyre D., Carroll D., Ring C., and Martin U. The human nociceptive flexion reflex threshold is higher during systole than diastole. Psychophysiology 39 (2002) 678-681
12. Edwards L., Ring C., McIntyre D., and Carroll D. Modulation of the human nociceptive flexion reflex across the cardiac cycle. Psychophysiology 38 (2001) 712-718
13. France C.R., al'absi M., Ring C., France J.L., Brose J., Spaeth D., Harju A., Nordehn G., and Wittmers L.E. Assessment of opiate modulation of pain and nociceptive responding in young adults with a parental history of hypertension. Biol Psychol 70 (2005) 168-174
14. France C.R., France J.L., al'Absi M., Ring C., and McIntyre D. Catastrophizing is related to pain ratings, but not nociceptive flexion reflex threshold. Pain 99 (2002) 459-463
15. France C.R., Froese S.A., and Stewart J.C. Altered central nervous system processing of noxious stimuli contributes to decreased nociceptive responding in individuals at risk for hypertension. Pain 98 (2002) 101-108
16. France C.R., and Suchowiecki S. Assessing supraspinal modulation of pain perception in individuals at risk for hypertension. Psychophysiology 38 (2001) 107-113
17. Guieu R., Blin O., Pouget J., and Serratrice G. Nociceptive threshold and physical activity. Can J Neurol Sci 19 (1992) 69-71
18. Guieu R., Blin P., Pouget J., and Serratrice G. High level sportsmen and nociceptive flexion reflex of the lower limb. Can J Neurosci 19 (1992) 69-71
19. Knutson L.M., Soderberg G.L., Ballantyne B.T., and Clarke W.R. A study of various normalization procedures for within day electromyographic data. J Electromyogr Kinesiol 1 (1994) 47-59
20. Page G.D., and France C.R. Objective evidence of decreased pain perception in normotensives at risk for hypertension. Pain 73 (1997) 173-180
21. Rainville P., Bushnell M.C., Duncan G.H., Casey K.L., and Bushnell M.C. PET studies of the subjective experience of pain (2000), IASP Press, Seattle, WA, US
22. Rainville P., Duncan G.H., Price D.D., Carrier B., and Bushnell M.C. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 277 (1997) 968-971
23. Rhudy J.L., Arnau R.C., Green B.A., and France C.R. Taxometric analysis of biceps femoris EMG following electrocutaneous stimulation over the sural nerve: determining the latent structure of the nociceptive flexion reflex (NFR). Int J Psychophysiol 69 (2008) 18-26
24. Rhudy J.L., and France C.R. Defining the nociceptive flexion reflex (NFR) threshold in human participants: a comparison of different scoring criteria. Pain 128 (2007) 244-253
25. Rhudy JL, France CR, Bartley EJ, McCabe KM, Williams AE. Psychophysiological responses to pain: further validation of the nociceptive flexion reflex (NFR) as a measure of nociception using multilevel modeling. Psychophysiology 2009. [Epub ahead of print], PMID: 19497013.
26. Rhudy J.L., Williams A.E., McCabe K., Nguyen M.A., and Rambo P. Affective modulation of nociception at spinal and supraspinal levels. Psychophysiology 42 (2005) 579-587
27. Sandrini G., Serrao M., Rossi P., Romaniello A., Cruccu G., and Willer J.C. The lower limb flexion reflex in humans. Prog Neurobiol 77 (2005) 353-395
28. Skljarevski V., and Ramadan N.M. The nociceptive flexion reflex in humans - review article. Pain 96 (2002) 3-8
29. Terkelsen A.J., Andersen O.K., MÃ̧lgaard H., Hansen J., and Jensen T.S. Mental stress inhibits pain perception and heart rate variability but not a nociceptive withdrawal reflex. Acta Physiol Scand 180 (2004) 405-414
30. Tracey I., Becerra L., Chang I., Breiter H., Jenkins L., Borsook D., and Gonzalez R.G. Noxious hot and cold stimulation produce common patterns of brain activation in humans: a functional magnetic resonance imaging study. Neurosci Lett 288 (2000) 159
31. Willer J.C. Comparative study of perceived pain and nociceptive flexion reflex in man. Pain 3 (1977) 69-80
32. Willer J.C., Boureau F., and Albe-Fessard D. Supraspinal influences on nociceptive flexion reflex and pain sensation in man. Brain Res 179 (1979) 61-68
33. Yang J.F., and Winter D.A. Electromyographic amplitude normalization methods: improving their sensitivity as diagnostic tools in gait analysis. Arch Phys Med Rehabil 65 (1984) 517-521
34. Zubieta J.K., Smith Y.R., Bueller J.A., Xu Y., Kilbourn M.R., Jewett D.M., Meyer C.R., Koeppe R.A., and Stohler C.S. Regional mu opioid receptor regulation of sensory and affective dimensions of pain. Science 293 (2001) 311-315