Combined genetic analysis of sputum and computed tomography for noninvasive diagnosis of non-small-cell lung cancer

Lung Cancer

Volumn 66, Issue 1, 2009, Pages 58-63

  Jiang, Feng ^a   Todd, Nevins W ^a   Qiu, Qi ^a   Liu, Zhenqiu ^b   Katz, Ruth L ^c   Stass, Sanford A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BALTIMORE   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

CT; Diagnosis; Genetic analysis; Lung cancer; Sputum

Indexed keywords

FRAGILE HISTIDINE TRIAD PROTEIN; HYALURONOGLUCOSAMINIDASE; HYALURONOGLUCOSAMINIDASE 2; PROTEIN P16; SURFACTANT PROTEIN A; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER STAGING; CHROMOSOME 10Q; CHROMOSOME 3P; CHROMOSOME 9P; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; FEMALE; GENETIC ANALYSIS; HUMAN; LARGE CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MALE; NON INVASIVE MEASUREMENT; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SPUTUM ANALYSIS;

AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; GENE EXPRESSION PROFILING; GENES, NEOPLASM; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SPUTUM; TOMOGRAPHY, X-RAY COMPUTED; TUMOR MARKERS, BIOLOGICAL;

EID: 68949219743     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2009.01.004     Document Type: Article

References (26)

1. Greenlee R.T., Hill-Harmon M.B., Murray T., et al. Cancer statistics. CA Cancer J Clin 51 (2001) 15-36
2. Frost J.K., Ball Jr. W.C., Levin M.L., et al. Early lung cancer detection: results of the initial (prevalence) radiologic and cytologic screening in the Johns Hopkins study. Am Rev Respir Dis 130 (1984) 549-554
3. Hirsch F.R., Franklin W.A., Gazdar A.F., and Bunn Jr. P.A. Early detection of lung cancer: clinical perspectives of recent advances in biology and radiology. Clin Cancer Res 7 (2001) 5-22
4. Toloza E.M., Harpole L., and McCrory D.C. Noninvasive staging of non-small cell lung cancer: a review of the current evidence. Chest 123 (2003) 137S-146S
5. Saccomanno G., Archer V.E., Auerbach O., Saunders R.P., and Brennan L.M. Development of carcinoma of the lung as reflected in exfoliated cells. Cancer 33 (1974) 256-270
6. Thunnissen F.B. Sputum examination for early detection of lung cancer. J Clin Pathol 11 (2003) 805-810
7. Belinsky S.A. Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 4 (2004) 707-717
8. Jiang F., Yin Z., Caraway N.P., Li R., and Katz R.L. Genomic profiles in stage I primary non small cell lung cancer using comparative genomic hybridization analysis of cDNA microarrays. Neoplasia 6 (2004) 623-635
9. Li R., Wang H., Bekele B.N., Yin Z., Caraway N.P., Katz R.L., et al. Identification of putative oncogenes in lung adenocarcinoma by a comprehensive functional genomic approach. Oncogene 18 (2006) 2628-2635
10. Li R., Todd N.W., Qiu Q., Fan T., Zhao R.Y., Rodgers W.H., et al. Genetic deletions in sputum as diagnostic markers for early detection of stage I non-small cell lung cancer. Clin Cancer Res 13 (2007) 482-487
11. Li R., Liu Z., Fan T., and Jiang F. A novel multiple FISH array for the detection of genetic aberrations in cancer. Lab Invest 86 (2006) 619-627
12. Jiang F. In-situ genomic DNA chip for detection of cancer. United States Patent 20,070,178,503; 2007.
13. Qiu Q., Todd N.W., Li R., Peng H., Liu Z., Yfantis H.G., et al. Magnetic enrichment of bronchial epithelial cells from sputum for lung cancer diagnosis. Cancer 114 (2008) 275-283
14. Brambilla E., Travis W.D., Colby T.V., Corrin B., and Shimosato Y. The new World Health Organization classification of lung tumours. Eur Respir J 18 (2001) 1059-1068
15. Mountain C.F. Revisions in the International System for Staging Lung Cancer. Chest 6 (1997) 1710-1717
16. Diederich S., Wormanns D., Semik M., Thomas M., Lenzen H., Roos N., et al. Screening for early lung cancer with low-dose spiral CT: prevalence in 817 asymptomatic smokers. Radiology 222 (2002) 773-781
17. Lerman M.I., and Minna J.D. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium. Cancer Res 60 (2000) 6116-6133
18. Senchenko V.N., Liu J., Loginov W., Bazov I., Angeloni D., Seryogin Y., et al. Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung, and breast carcinomas. Oncogene 29 (2004) 5719-5728
19. Croce C.M., Sozzi G., and Huebner K. Role of FHIT in human cancer. J Clin Oncol 17 (1999) 1618-1624
20. Iwakawa R., Kohno T., Anami Y., Noguchi M., Suzuki K., Matsuno Y., et al. Association of p16 homozygous deletions with clinicopathologic characteristics and EGFR/KRAS/p53 mutations in lung adenocarcinoma. Clin Cancer Res 12 (2008) 3746-3753
21. Bruns G., Stroh H., Veldman G.M., Latt S.A., and Floros J. The 35 kd pulmonary surfactant-associated protein is encoded on chromosome 10. Hum Genet 76 (1987) 58-62
22. Jiang F., Caraway N.P., Nebiyou Bekele B., Zhang H.Z., Khanna A., Wang H., et al. Surfactant protein A gene deletion and prognostics for patients with stage I non-small cell lung cancer. Clin Cancer Res 11 (2005) 5417-5424
23. Katz R.L., Zaidi T.M., Fernandez R.L., Zhang J., He W., Acosta C., et al. Automated detection of genetic abnormalities combined with cytology in sputum is a sensitive predictor of lung cancer. Mod Pathol 8 (2008) 950-960
24. Byers T., Wolf H.J., Franklin W.A., Braudrick S., Merrick D.T., Shroyer K.R., et al. Sputum cytologic atypia predicts incident lung cancer: defining latency and histologic specificity. Cancer Epidemiol Biomarkers Prev 17 (2008) 158-162
25. Wallace M.B., Pascual J.M., Raimondo M., Woodward T.A., McComb B.L., Crook J.E., et al. Minimally invasive endoscopic staging of suspected lung cancer. JAMA 299 (2008) 540-546
26. Vansteenkiste J.F., and Stroobants S.S. PET scan in lung cancer: current recommendations and innovation. J Thorac Oncol 1 (2006) 71-73