Investigation of Sudan IV staining areas in aortas of infants and children: Possible prelesional stages of atherogenesis

Atherosclerosis

Volumn 206, Issue 1, 2009, Pages 159-167

  Torzewski, Michael ^a   Navarro, Bianca ^a   Cheng, Fei ^a   Canisius, Antje ^a   Schmidt, Talkea ^a   Bhakdi, Sucharit ^a   Urban, Reinhard ^a   Lackner, Karl J ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Atherogenesis; C reactive protein; Children; Complement system; Enzymatically modified LDL; Infants; Macrophages; Oxidatively modified LDL

Indexed keywords

APOLIPOPROTEIN B; C REACTIVE PROTEIN; COMPLEMENT; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; SCARLET RED;

ADOLESCENT; AORTA; ARTERY INTIMA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CHILD; COMPLEMENT ACTIVATION; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; INFLAMMATION; LIPID STORAGE; MACROPHAGE ACTIVATION; MAJOR CLINICAL STUDY; MALE; MONOCYTE; NEWBORN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER;

ADOLESCENT; AORTA; AORTA, THORACIC; APOLIPOPROTEINS B; ATHEROSCLEROSIS; AZO COMPOUNDS; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MACROPHAGES; MALE; MONOCYTES; TUNICA INTIMA;

EID: 68949219638     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.01.038     Document Type: Article

References (38)

1. Williams K.J., and Tabas I. The response-to-retention hypothesis of atherogenesis reinforced. Curr Opin Lipidol 9 (1998) 471-474
2. Seifert P.S., Hugo F., Tranum-Jensen J., et al. Isolation and characterization of a complement-activating lipid extracted from human atherosclerotic lesions. J Exp Med 172 (1990) 547-557
3. Bhakdi S., Dorweiler B., Kirchmann R., et al. On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety. J Exp Med 182 (1995) 1959-1971
4. Torzewski M., Klouche M., Hock J., et al. Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesion. Arterioscler Thromb Vasc Biol 18 (1998) 369-378
5. Bhakdi S., Lackner K.J., Han S.R., Torzewski M., and Husmann M. Beyond cholesterol: the enigma of atherosclerosis revisited. Thromb Haemost 91 (2004) 639-645
6. Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352 (2005) 1685-1695
7. Torzewski M., and Lackner K.J. Initiation and progression of atherosclerosis-enzymatic or oxidative modification of low-density lipoprotein?. Clin Chem Lab Med 44 (2006) 1389-1394
8. Stary H.C. Lipid and macrophage accumulations in arteries of children and the development of atherosclerosis. Am J Clin Nutr 72 (2000) 1297S-1306S
9. Stary H.C. Natural history and histological classification of atherosclerotic lesions: an update. Arterioscler Thromb Vasc Biol 20 (2000) 1177-1178
10. Wissler R.W., and Strong J.P. Risk factors and progression of atherosclerosis in youth. PDAY Research Group. Pathological Determinants of Atherosclerosis in Youth. Am J Pathol 153 (1998) 1023-1033
11. Velican C., and Velican D. Coronary arteries in children up to the age of ten years. II. Intimal thickening and its role in atherosclerotic involvement. Med Intern 14 (1976) 17-24
12. Sakurai I., Tosaka A., Yamada T., Kuwahara T., and Masubuchi K. Childhood coronary sclerosis. Acta Pathol Jpn 28 (1978) 41-52
13. Bland J., Skordalaki A., and Emery J.L. Early intimal lesions in the common carotid artery. Cardiovasc Res 20 (1986) 863-868
14. Stary H.C. Macrophages, macrophage foam cells, and eccentric intimal thickening in the coronary arteries of young children. Atherosclerosis 64 (1987) 91-108
15. Napoli C., D'Armiento F.P., Mancini F.P., et al. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J Clin Invest 100 (1997) 2680-2690
16. Napoli C., Glass C.K., Witztum J.L., Deutsch R., D'Armiento F.P., and Palinski W. Influence of maternal hypercholesterolaemia during pregnancy on progression of early atherosclerotic lesions in childhood: fate of early lesions in children (FELIC) study. Lancet 354 (1999) 1234-1241
17. Lehr H.A., Sagban T.A., Ihling C., et al. Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet. Circulation 104 (2001) 914-920
18. Pessanha B.S., Potter K., Kolodgie F.D., et al. Characterization of intimal changes in coronary artery specimens with MR microscopy. Radiology 241 (2006) 107-115
19. Hugo F., Jenne D., and Bhakdi S. Monoclonal antibodies against neoantigens of the terminal C5b-9 complex of human complement. Biosci Rep 5 (1985) 649-658
20. Palinski W., Yla-Herttuala S., Rosenfeld M.E., et al. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein. Arteriosclerosis 10 (1990) 325-335
21. Palinski W., Horkko S., Miller E., et al. Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma. J Clin Invest 98 (1996) 800-814
22. Stary H.C., Blankenhorn D.H., Chandler A.B., et al. A definition of the intima of human arteries and of its atherosclerosis-prone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 85 (1992) 391-405
23. Wyler von Ballmoos M., Dubler D., Mirlacher M., et al. Increased apolipoprotein deposits in early atherosclerotic lesions distinguish symptomatic from asymptomatic patients. Arterioscler Thromb Vasc Biol 26 (2006) 359-364 Epub 2005 Dec 2001
24. Bhakdi S., Torzewski M., Klouche M., and Hemmes M. Complement and atherogenesis: binding of CRP to degraded, nonoxidized LDL enhances complement activation. Arterioscler Thromb Vasc Biol 19 (1999) 2348-2354
25. Han S.R., Momeni A., Strach K., et al. Enzymatically modified LDL induces cathepsin H in human monocytes: potential relevance in early atherogenesis. Arterioscler Thromb Vasc Biol 23 (2003) 661-667
26. Bhakdi S., Torzewski M., Paprotka K., et al. Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequence. Circulation 109 (2004) 1870-1876 Epub 2004 Mar 1822
27. Torzewski M., Suriyaphol P., Paprotka K., et al. Enzymatic modification of low-density lipoprotein in the arterial wall: a new role for plasmin and matrix metalloproteinases in atherogenesis. Arterioscler Thromb Vasc Biol 24 (2004) 2130-2136 Epub 2004 Sep 2132
28. Chang M.K., Binder C.J., Torzewski M., and Witztum J.L. C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: phosphorylcholine of oxidized phospholipids. Proc Natl Acad Sci USA 99 (2002) 13043-13048
29. Torzewski M., Torzewski J., Bowyer D.E., et al. Immunohistochemical colocalization of the terminal complex of human complement and smooth muscle cell alpha-actin in early atherosclerotic lesions. Arterioscler Thromb Vasc Biol 17 (1997) 2448-2452
30. Torzewski J., Torzewski M., Bowyer D.E., et al. C-reactive protein frequently colocalizes with the terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries. Arterioscler Thromb Vasc Biol 18 (1998) 1386-1392
31. Torzewski M., Rist C., Mortensen R.F., et al. C-reactive protein in the arterial intima: role of C-reactive protein receptor-dependent monocyte recruitment in atherogenesis. Arterioscler Thromb Vasc Biol 20 (2000) 2094-2099
32. Nakashima Y., Fujii H., Sumiyoshi S., Wight T.N., and Sueishi K. Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration. Arterioscler Thromb Vasc Biol 27 (2007) 1159-1165 Epub 2007 Feb 1115
33. Kolodgie F.D., Burke A.P., Nakazawa G., and Virmani R. Is pathologic intimal thickening the key to understanding early plaque progression in human atherosclerotic disease?. Arterioscler Thromb Vasc Biol 27 (2007) 986-989
34. Parmar N., Albisetti M., Berry L.R., and Chan A.K. The fibrinolytic system in newborns and children. Clin Lab 52 (2006) 115-124
35. Vlaicu R., Niculescu F., Rus H.G., and Cristea A. Immunohistochemical localization of the terminal C5b-9 complement complex in human aortic fibrous plaque. Atherosclerosis 57 (1985) 163-177
36. Schmiedt W., Kinscherf R., Deigner H.P., et al. Complement C6 deficiency protects against diet-induced atherosclerosis in rabbits. Arterioscler Thromb Vasc Biol 18 (1998) 1790-1795
37. Lehr H.A., Mankoff D.A., Corwin D., Santeusanio G., and Gown A.M. Application of photoshop-based image analysis to quantification of hormone receptor expression in breast cancer. J Histochem Cytochem 45 (1997) 1559-1565
38. Lehr H.A., van der Loos C.M., Teeling P., and Gown A.M. Complete chromogen separation and analysis in double immunohistochemical stains using Photoshop-based image analysis. J Histochem Cytochem 47 (1999) 119-126